Regulation of glut1 mRNA by hypoxia-inducible factor-1: interaction between H-ras and hypoxia C Chen, N Pore, A Behrooz, F Ismail-Beigi, A Maity Journal of Biological Chemistry 276 (12), 9519-9525, 2001 | 1023 | 2001 |
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving … A Maity, N Pore, J Lee, D Solomon, DM O’Rourke Cancer research 60 (20), 5879-5886, 2000 | 354 | 2000 |
EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1–independent and HIF-1–dependent mechanisms N Pore, Z Jiang, A Gupta, G Cerniglia, GD Kao, A Maity Cancer research 66 (6), 3197-3204, 2006 | 338 | 2006 |
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1–independent mechanism N Pore, S Liu, HK Shu, B Li, D Haas-Kogan, D Stokoe, J Milanini-Mongiat, ... Molecular biology of the cell 15 (11), 4841-4853, 2004 | 295 | 2004 |
Akt1 activation can augment hypoxia-inducible factor-1α expression by increasing protein translation through a mammalian target of rapamycin–independent pathway N Pore, Z Jiang, HK Shu, E Bernhard, GD Kao, A Maity Molecular cancer research 4 (7), 471-479, 2006 | 233 | 2006 |
PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating … N Pore, S Liu, DA Haas-Kogan, DM O’Rourke, A Maity Cancer research 63 (1), 236-241, 2003 | 214 | 2003 |
Nelfinavir down-regulates hypoxia-inducible factor 1α and VEGF expression and increases tumor oxygenation: implications for radiotherapy N Pore, AK Gupta, GJ Cerniglia, Z Jiang, EJ Bernhard, SM Evans, ... Cancer research 66 (18), 9252-9259, 2006 | 189 | 2006 |
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir Z Jiang, N Pore, GJ Cerniglia, R Mick, MM Georgescu, EJ Bernhard, ... Cancer research 67 (9), 4467-4473, 2007 | 161 | 2007 |
Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy GJ Cerniglia, N Pore, JH Tsai, S Schultz, R Mick, R Choe, X Xing, ... PloS one 4 (8), e6539, 2009 | 156 | 2009 |
M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo JM Curry, TD Eubank, RD Roberts, Y Wang, N Pore, A Maity, CB Marsh PloS one 3 (10), e3405, 2008 | 136 | 2008 |
HIV protease inhibitors decrease VEGF/HIF-1α expression and angiogenesis in glioblastoma cells N Pore, AK Gupta, GJ Cerniglia, A Maity Neoplasia 8 (11), 889-895, 2006 | 115 | 2006 |
Regulation of histone deacetylase 4 expression by the SP family of transcription factors F Liu, N Pore, M Kim, KR Voong, M Dowling, A Maity, GD Kao Molecular biology of the cell 17 (2), 585-597, 2006 | 66 | 2006 |
Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional STK11 Mutations in Patients with Non–Small Cell Lung Cancer and … N Pore, S Wu, N Standifer, M Jure-Kunkel, M de Los Reyes, Y Shrestha, ... Cancer Discovery 11 (11), 2828-2845, 2021 | 61 | 2021 |
Phase 1, first-in-human study of MEDI2228, a BCMA-targeted ADC in patients with relapsed/refractory multiple myeloma SK Kumar, M Migkou, M Bhutani, A Spencer, S Ailawadhi, A Kalff, ... Blood 136, 26-27, 2020 | 56 | 2020 |
Anti-ADAM17 monoclonal antibody MEDI3622 increases IFNγ production by human NK cells in the presence of antibody-bound tumor cells HK Mishra, N Pore, EF Michelotti, B Walcheck Cancer Immunology, Immunotherapy 67, 1407-1416, 2018 | 51 | 2018 |
Activation of ADAM17 by IL-15 limits human NK cell proliferation HK Mishra, KJ Dixon, N Pore, M Felices, JS Miller, B Walcheck Frontiers in immunology 12, 711621, 2021 | 21 | 2021 |
Blocking adam17 function with a monoclonal antibody improves sepsis survival in a murine model of polymicrobial sepsis HK Mishra, J Ma, D Mendez, R Hullsiek, N Pore, B Walcheck International journal of molecular sciences 21 (18), 6688, 2020 | 19 | 2020 |
In vivo loss of function screening reveals carbonic anhydrase IX as a key modulator of tumor initiating potential in primary pancreatic tumors N Pore, S Jalla, Z Liu, B Higgs, C Sorio, A Scarpa, R Hollingsworth, ... Neoplasia 17 (6), 473-480, 2015 | 14 | 2015 |
The chemokine receptor CXCR4: a homing device for hypoxic cancer cells? N Pore, A Maity Cancer biology & therapy 5 (11), 1563-1565, 2006 | 12 | 2006 |
Discovery and development of MEDI7247, a novel pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2, for treating hematological cancers N Pore, KP Schifferli, NR Monks, R Tammali, M Borrok, E Hurt, M Flynn, ... Blood 132, 4071, 2018 | 10 | 2018 |