| ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death J Han, SH Back, J Hur, YH Lin, R Gildersleeve, J Shan, CL Yuan, ... Nature cell biology 15 (5), 481-490, 2013 | 1687 | 2013 |
| The role of ER stress in lipid metabolism and lipotoxicity J Han, RJ Kaufman Journal of lipid research 57 (8), 1329-1338, 2016 | 601 | 2016 |
| Translation attenuation through eIF2α phosphorylation prevents oxidative stress and maintains the differentiated state in β cells SH Back, D Scheuner, J Han, B Song, M Ribick, J Wang, RD Gildersleeve, ... Cell metabolism 10 (1), 13-26, 2009 | 409 | 2009 |
| IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis S Wang, Z Chen, V Lam, J Han, J Hassler, BN Finck, NO Davidson, ... Cell metabolism 16 (4), 473-486, 2012 | 244 | 2012 |
| Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis YS Lee, S Shin, T Shigihara, E Hahm, MJ Liu, J Han, JW Yoon, HS Jun Diabetes 56 (6), 1671-1679, 2007 | 211 | 2007 |
| The IRE1α/XBP1s pathway is essential for the glucose response and protection of β cells JR Hassler, DL Scheuner, S Wang, J Han, VK Kodali, P Li, J Nguyen, ... PLoS biology 13 (10), e1002277, 2015 | 160 | 2015 |
| The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β‐cells RJ Kaufman, SH Back, B Song, J Han, J Hassler Diabetes, Obesity and Metabolism 12, 99-107, 2010 | 158 | 2010 |
| Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus J Yong, JD Johnson, P Arvan, J Han, RJ Kaufman Nature Reviews Endocrinology 17 (8), 455-467, 2021 | 148 | 2021 |
| Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response N Hiramatsu, C Messah, J Han, MM LaVail, RJ Kaufman, JH Lin Molecular biology of the cell 25 (9), 1411-1420, 2014 | 140 | 2014 |
| ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice J Han, R Murthy, B Wood, B Song, S Wang, B Sun, H Malhi, RJ Kaufman Diabetologia 56, 911-924, 2013 | 127 | 2013 |
| A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux D Krokowski, J Han, M Saikia, M Majumder, CL Yuan, BJ Guan, ... Journal of Biological Chemistry 288 (24), 17202-17213, 2013 | 120 | 2013 |
| Physiological/pathological ramifications of transcription factors in the unfolded protein response J Han, RJ Kaufman Genes & development 31 (14), 1417-1438, 2017 | 110 | 2017 |
| RNA surveillance is required for endoplasmic reticulum homeostasis K Sakaki, S Yoshina, X Shen, J Han, MR DeSantis, M Xiong, S Mitani, ... Proceedings of the National Academy of Sciences 109 (21), 8079-8084, 2012 | 103 | 2012 |
| Endoplasmic Reticulum Stress in the β‐Cell Pathogenesis of Type 2 Diabetes SH Back, SW Kang, J Han, HT Chung Journal of Diabetes Research 2012 (1), 618396, 2012 | 100 | 2012 |
| Effect of p38 mitogen-activated protein kinase on the replication of encephalomyocarditis virus K Hirasawa, A Kim, HS Han, J Han, HS Jun, JW Yoon Journal of virology 77 (10), 5649-5656, 2003 | 98 | 2003 |
| Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein J Han, HY Yoo, BH Choi, HM Rho Biochemical and biophysical research communications 272 (2), 525-530, 2000 | 91 | 2000 |
| C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitis H Malhi, EM Kropp, VF Clavo, CR Kobrossi, JS Han, AS Mauer, J Yong, ... Journal of Biological Chemistry 288 (26), 18624-18642, 2013 | 89 | 2013 |
| ER stress induces cell cycle arrest at the G2/M phase through eIF2α phosphorylation and GADD45α D Lee, D Hokinson, S Park, R Elvira, F Kusuma, JM Lee, M Yun, SG Lee, ... International journal of molecular sciences 20 (24), 6309, 2019 | 85 | 2019 |
| Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase HS Jun, YH Chung, J Han, A Kim, S Yoo, R Sherwin, JW Yoon Diabetologia 45, 668-676, 2002 | 79 | 2002 |
| Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice MS Ko, JY Yun, IJ Baek, JE Jang, JJ Hwang, SE Lee, SH Heo, DA Bader, ... Autophagy 17 (5), 1205-1221, 2021 | 75 | 2021 |
Maureen A SartorProfessor of Bioinformatics, University of Michigan在 umich.edu 的电子邮件经过验证
