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Alberto Bardelli
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Detection of circulating tumor DNA in early-and late-stage human malignancies
C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ...
Science translational medicine 6 (224), 224ra24-224ra24, 2014
49062014
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
Y Samuels, Z Wang, A Bardelli, N Silliman, J Ptak, S Szabo, H Yan, ...
Science 304 (5670), 554-554, 2004
43472004
ESMO consensus guidelines for the management of patients with metastatic colorectal cancer
E Van Cutsem, A Cervantes, R Adam, A Sobrero, JH Van Krieken, ...
Annals of Oncology 27 (8), 1386-1422, 2016
35672016
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective …
W De Roock, B Claes, D Bernasconi, J De Schutter, B Biesmans, ...
The lancet oncology 11 (8), 753-762, 2010
26002010
Liquid biopsies: genotyping circulating tumor DNA
LA Diaz Jr, A Bardelli
Journal of clinical oncology 32 (6), 579-586, 2014
24092014
Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR
A Prahallad, C Sun, S Huang, F Di Nicolantonio, R Salazar, D Zecchin, ...
Nature 483 (7387), 100-103, 2012
22182012
Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer
F Di Nicolantonio, M Martini, F Molinari, A Sartore-Bianchi, S Arena, ...
Journal of clinical oncology 26 (35), 5705-5712, 2008
21832008
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ...
Nature 486 (7404), 532-536, 2012
20682012
Liquid biopsy: monitoring cancer-genetics in the blood
E Crowley, F Di Nicolantonio, F Loupakis, A Bardelli
Nature reviews Clinical oncology 10 (8), 472-484, 2013
19902013
Integrating liquid biopsies into the management of cancer
G Siravegna, S Marsoni, S Siena, A Bardelli
Nature reviews Clinical oncology 14 (9), 531-548, 2017
18392017
RAF/RAS oncogenes and mismatch-repair status
H Rajagopalan, A Bardelli, C Lengauer, KW Kinzler, B Vogelstein, ...
Nature 418 (6901), 934-934, 2002
16622002
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
C Ponzetto, A Bardelli, Z Zhen, F Maina, P dalla Zonca, S Giordano, ...
Cell 77 (2), 261-271, 1994
12241994
Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study
M Moroni, S Veronese, S Benvenuti, G Marrapese, A Sartore-Bianchi, ...
The lancet oncology 6 (5), 279-286, 2005
11782005
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
G Siravegna, B Mussolin, M Buscarino, G Corti, A Cassingena, ...
Nature medicine 21 (7), 795-801, 2015
11312015
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti–epidermal growth factor receptor antibody therapies
S Benvenuti, A Sartore-Bianchi, F Di Nicolantonio, C Zanon, M Moroni, ...
Cancer research 67 (6), 2643-2648, 2007
10892007
A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D Corà, ...
Cancer discovery 1 (6), 508-523, 2011
10322011
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of …
A Sartore-Bianchi, L Trusolino, C Martino, K Bencardino, S Lonardi, ...
The Lancet Oncology 17 (6), 738-746, 2016
10052016
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
AN Hata, MJ Niederst, HL Archibald, M Gomez-Caraballo, FM Siddiqui, ...
Nature medicine 22 (3), 262-269, 2016
9652016
PIK3CA Mutations in Colorectal Cancer Are Associated with Clinical Resistance to EGFR-Targeted Monoclonal Antibodies
A Sartore-Bianchi, M Martini, F Molinari, S Veronese, M Nichelatti, ...
Cancer research 69 (5), 1851-1857, 2009
9352009
Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma
C Sun, L Wang, S Huang, GJJE Heynen, A Prahallad, C Robert, ...
Nature 508 (7494), 118-122, 2014
9132014
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