Human Survival Motor Neuron genes generate a vast repertoire of circular RNAs EW Ottesen, D Luo, J Seo, NN Singh, RN Singh Nucleic acids research 47 (6), 2884-2905, 2019 | 69 | 2019 |
1400W, a highly selective inducible nitric oxide synthase inhibitor is a potential disease modifier in the rat kainate model of temporal lobe epilepsy S Puttachary, S Sharma, S Verma, Y Yang, M Putra, A Thippeswamy, ... Neurobiology of disease 93, 184-200, 2016 | 62 | 2016 |
Pre-mRNA splicing modulation by antisense oligonucleotides NN Singh, D Luo, RN Singh Exon Skipping and Inclusion Therapies: Methods and Protocols, 415-437, 2018 | 37 | 2018 |
Mechanisms of neuronal alternative splicing and strategies for therapeutic interventions EJL Soto, MJ Gandal, T Gonatopoulos-Pournatzis, EA Heller, D Luo, ... Journal of Neuroscience 39 (42), 8193-8199, 2019 | 34 | 2019 |
Activation of a cryptic 5′ splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene NN Singh, JB Del Rio-Malewski, D Luo, EW Ottesen, MD Howell, ... Nucleic Acids Research 45 (21), 12214-12240, 2017 | 31 | 2017 |
High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs EW Ottesen, NN Singh, D Luo, RN Singh Nucleic acids research 46 (20), 10983-11001, 2018 | 26 | 2018 |
Diverse targets of SMN2-directed splicing-modulating small molecule therapeutics for spinal muscular atrophy EW Ottesen, NN Singh, D Luo, B Kaas, BJ Gillette, J Seo, HJ Jorgensen, ... Nucleic Acids Research 51 (12), 5948-5980, 2023 | 16 | 2023 |
High concentration of an ISS-N1-targeting antisense oligonucleotide causes massive perturbation of the transcriptome EW Ottesen, D Luo, NN Singh, RN Singh International Journal of Molecular Sciences 22 (16), 8378, 2021 | 15 | 2021 |
Off-Target drug effects resulting in altered gene expression events with epigenetic and Quasi-Epigenetic origins SJ Anderson, KM Feye, GR Schmidt-McCormack, E Malovic, ... Pharmacological research 107, 229-233, 2016 | 15 | 2016 |
Internal introns promote backsplicing to generate circular RNAs from spinal muscular atrophy gene D Luo, NN Singh, RN Singh Genes 13 (7), 1145, 2022 | 5 | 2022 |
A super minigene with a short promoter and truncated introns recapitulates essential features of transcription and splicing regulation of the SMN1 and SMN2 genes EW Ottesen, J Seo, D Luo, NN Singh, RN Singh Nucleic Acids Research 52 (7), 3547-3571, 2024 | 3 | 2024 |
Veterinary considerations for the theoretical resurrection of extinct species KM Feye, JS Smith, L Sebbag, AE Hohman, S Acharya J Vet Sci Ani Husb 6 (3), 306, 2018 | 1 | 2018 |
Transcriptome-and proteome-wide effects of a circular RNA encompassing four early exons of the spinal muscular atrophy genes D Luo, EW Ottesen, JH Lee, RN Singh Scientific Reports 14 (1), 10442, 2024 | | 2024 |
Theoretical Engineering of the Gut Micro biome for the Purpose of Creating Superior Soldiers G Schmidt-McCormack, K Feye, S Acharya, G Mlynarczyk, S Anderson, ... | | 2017 |