Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes B Marcheva, KM Ramsey, ED Buhr, Y Kobayashi, H Su, CH Ko, G Ivanova, ... Nature 466 (7306), 627-631, 2010 | 1686 | 2010 |
Insulin gene mutations as a cause of permanent neonatal diabetes J Støy, EL Edghill, SE Flanagan, H Ye, VP Paz, A Pluzhnikov, JE Below, ... Proceedings of the National Academy of Sciences 104 (38), 15040-15044, 2007 | 676 | 2007 |
Insulin Mutation Screening in 1,044 Patients With Diabetes: Mutations in the INS Gene Are a Common Cause of Neonatal Diabetes but a Rare Cause of Diabetes … EL Edghill, SE Flanagan, AM Patch, C Boustred, A Parrish, B Shields, ... Diabetes 57 (4), 1034-1042, 2008 | 479 | 2008 |
The mental health comorbidities of diabetes L Ducat, LH Philipson, BJ Anderson Jama 312 (7), 691-692, 2014 | 424 | 2014 |
Precision medicine in diabetes: a consensus report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) WK Chung, K Erion, JC Florez, AT Hattersley, MF Hivert, CG Lee, ... Diabetes care 43 (7), 1617-1635, 2020 | 410 | 2020 |
Intracellular transport of insulin granules is a subordinated random walk SMA Tabei, S Burov, HY Kim, A Kuznetsov, T Huynh, J Jureller, ... Proceedings of the National Academy of Sciences 110 (13), 4911-4916, 2013 | 385 | 2013 |
Conditional gene targeting in mouse pancreatic β-cells: analysis of ectopic Cre transgene expression in the brain B Wicksteed, M Brissova, W Yan, DM Opland, JL Plank, RB Reinert, ... Diabetes 59 (12), 3090-3098, 2010 | 382 | 2010 |
Structure and functional characterization of neuronal alpha 1E calcium channel subtypes. ME Williams, LM Marubio, CR Deal, M Hans, PF Brust, LH Philipson, ... Journal of Biological Chemistry 269 (35), 22347-22357, 1994 | 329 | 1994 |
Visualizing superoxide production in normal and diabetic rat islets of Langerhans VP Bindokas, A Kuznetsov, S Sreenan, KS Polonsky, MW Roe, ... Journal of Biological Chemistry 278 (11), 9796-9801, 2003 | 287 | 2003 |
Loss of HNF-1α function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism DQ Shih, S Screenan, KN Munoz, L Philipson, M Pontoglio, M Yaniv, ... Diabetes 50 (11), 2472-2480, 2001 | 281 | 2001 |
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution D Chen, W Du, Y Liu, W Liu, A Kuznetsov, FE Mendez, LH Philipson, ... Proceedings of the National Academy of Sciences 105 (44), 16843-16848, 2008 | 277 | 2008 |
Update on diabetes classification CC Thomas, LH Philipson Medical Clinics 99 (1), 1-16, 2015 | 263 | 2015 |
Reactive species and early manifestation of insulin resistance in type 2 diabetes LE Fridlyand, LH Philipson Diabetes, Obesity and Metabolism 8 (2), 136-145, 2006 | 262 | 2006 |
Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes A Molven, M Ringdal, AM Nordbø, H Ræder, J Støy, GM Lipkind, ... Diabetes 57 (4), 1131-1135, 2008 | 260 | 2008 |
Localization of the Kv1. 5 K+ channel protein in explanted cardiac tissue. DJ Mays, JM Foose, LH Philipson, MM Tamkun The Journal of clinical investigation 96 (1), 282-292, 1995 | 256 | 1995 |
Intraperitoneal injection into adult zebrafish MD Kinkel, SC Eames, LH Philipson, VE Prince JoVE (Journal of Visualized Experiments), e2126, 2010 | 248 | 2010 |
Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis SC Eames, LH Philipson, VE Prince, MD Kinkel Zebrafish 7 (2), 205-213, 2010 | 247 | 2010 |
Effect of continuous glucose monitoring on hypoglycemia in older adults with type 1 diabetes: a randomized clinical trial RE Pratley, LG Kanapka, MR Rickels, A Ahmann, G Aleppo, R Beck, ... Jama 323 (23), 2397-2406, 2020 | 229 | 2020 |
Defective pancreatic β-cell glycolytic signaling in hepatocyte nuclear factor-1α-deficient mice ID Dukes, S Sreenan, MW Roe, M Levisetti, YP Zhou, D Ostrega, GI Bell, ... Journal of Biological Chemistry 273 (38), 24457-24464, 1998 | 219 | 1998 |
Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic β-cells? LE Fridlyand, LH Philipson Diabetes 53 (8), 1942-1948, 2004 | 211 | 2004 |