Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ... Alzheimer's research & therapy 9, 1-9, 2017 | 337 | 2017 |
In vivo quantification of neurofibrillary tangles with [18F]MK-6240 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... Alzheimer's research & therapy 10, 1-14, 2018 | 152 | 2018 |
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease TA Pascoal, S Mathotaarachchi, S Mohades, AL Benedet, CO Chung, ... Molecular psychiatry 22 (2), 306-311, 2017 | 136 | 2017 |
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ... Alzheimer's & dementia 16 (1), 192-199, 2020 | 131 | 2020 |
Identifying incipient dementia individuals using machine learning and amyloid imaging S Mathotaarachchi, TA Pascoal, M Shin, AL Benedet, MS Kang, ... Neurobiology of aging 59, 80-90, 2017 | 121 | 2017 |
Synergistic interaction between amyloid and tau predicts the progression to dementia TA Pascoal, S Mathotaarachchi, M Shin, AL Benedet, S Mohades, ... Alzheimer's & Dementia 13 (6), 644-653, 2017 | 117 | 2017 |
Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease KP Ng, TA Pascoal, S Mathotaarachchi, CO Chung, AL Benedet, M Shin, ... Neurology 88 (19), 1814-1821, 2017 | 83 | 2017 |
VoxelStats: a MATLAB package for multi-modal voxel-wise brain image analysis S Mathotaarachchi, S Wang, M Shin, TA Pascoal, AL Benedet, MS Kang, ... Frontiers in neuroinformatics 10, 20, 2016 | 83 | 2016 |
Aβ-induced vulnerability propagates via the brain’s default mode network TA Pascoal, S Mathotaarachchi, MS Kang, S Mohaddes, M Shin, AY Park, ... Nature communications 10 (1), 2353, 2019 | 68 | 2019 |
Anosognosia predicts default mode network hypometabolism and clinical progression to dementia J Therriault, KP Ng, TA Pascoal, S Mathotaarachchi, MS Kang, H Struyfs, ... Neurology 90 (11), e932-e939, 2018 | 65 | 2018 |
Dissociation between brain amyloid deposition and metabolism in early mild cognitive impairment L Wu, J Rowley, S Mohades, A Leuzy, MT Dauar, M Shin, V Fonov, J Jia, ... PLoS One 7 (10), e47905, 2012 | 58 | 2012 |
Imaging Alzheimer's disease pathophysiology with PET LP Schilling, ER Zimmer, M Shin, A Leuzy, TA Pascoal, AL Benedet, ... Dementia & neuropsychologia 10 (02), 79-90, 2016 | 56 | 2016 |
Multimodal imaging in rat model recapitulates Alzheimer's disease biomarkers abnormalities MJ Parent, ER Zimmer, M Shin, MS Kang, VS Fonov, A Mathieu, A Aliaga, ... Journal of Neuroscience 37 (50), 12263-12271, 2017 | 49 | 2017 |
White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer’s disease J Rowley, V Fonov, O Wu, SF Eskildsen, D Schoemaker, L Wu, ... PloS one 8 (9), e74776, 2013 | 37 | 2013 |
Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer’s disease MS Kang, AA Aliaga, M Shin, S Mathotaarachchi, AL Benedet, TA Pascoal, ... Molecular Psychiatry 26 (10), 5989-6001, 2021 | 30 | 2021 |
Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer’s disease TA Pascoal, S Mathotaarachchi, M Shin, AY Park, S Mohades, ... European journal of nuclear medicine and molecular imaging 45, 1021-1030, 2018 | 30 | 2018 |
Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [18F] THK5351 uptake in progressive supranuclear palsy KP Ng, J Therriault, MS Kang, H Struyfs, TA Pascoal, S Mathotaarachchi, ... NeuroImage: Clinical 24, 102091, 2019 | 25 | 2019 |
Regional amyloid-β load and white matter abnormalities contribute to hypometabolism in Alzheimer’s dementia LP Schilling, TA Pascoal, ER Zimmer, S Mathotaarachchi, M Shin, ... Molecular neurobiology 56 (7), 4916-4924, 2019 | 23 | 2019 |
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease TA Pascoal, M Chamoun, E Lax, HY Wey, M Shin, KP Ng, MS Kang, ... nature communications 13 (1), 4171, 2022 | 18 | 2022 |
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain. Alzheimers Res Ther. 2017; 9: 25 KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin PUBMED, 0 | 17 | |