Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis P Ding, Y Xu, L Li, X Lv, L Li, J Chen, D Zhou, X Wang, Q Wang, W Zhang, ... Cell reports 39 (9), 2022 | 68 | 2022 |
C5aR1 is a master regulator in colorectal tumorigenesis via immune modulation P Ding, L Li, L Li, X Lv, D Zhou, Q Wang, J Chen, C Yang, E Xu, W Dai, ... Theranostics 10 (19), 8619, 2020 | 65 | 2020 |
A novel FOXM1 isoform, FOXM1D, promotes epithelial–mesenchymal transition and metastasis through ROCKs activation in colorectal cancer X Zhang, L Zhang, Y Du, H Zheng, P Zhang, Y Sun, Y Wang, J Chen, ... Oncogene 36 (6), 807-819, 2017 | 60 | 2017 |
Inhibition of the PLK1‐coupled cell cycle machinery overcomes resistance to oxaliplatin in colorectal cancer Z Yu, P Deng, Y Chen, S Liu, J Chen, Z Yang, J Chen, X Fan, P Wang, ... Advanced science 8 (23), 2100759, 2021 | 58 | 2021 |
FOXM1D potentiates PKM2‐mediated tumor glycolysis and angiogenesis W Zhang, X Zhang, S Huang, J Chen, P Ding, Q Wang, L Li, X Lv, L Li, ... Molecular Oncology 15 (5), 1466-1485, 2021 | 47 | 2021 |
CD59 regulation by SOX2 is required for epithelial cancer stem cells to evade complement surveillance J Chen, P Ding, L Li, H Gu, X Zhang, L Zhang, N Wang, L Gan, Q Wang, ... Stem cell reports 8 (1), 140-151, 2017 | 45 | 2017 |
NF-κB and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack Y Du, X Teng, N Wang, X Zhang, J Chen, P Ding, Q Qiao, Q Wang, ... Journal of Biological Chemistry 289 (5), 2711-2724, 2014 | 45 | 2014 |
PI3K/AKT inhibition reverses R-CHOP resistance by destabilizing SOX2 in diffuse large B cell lymphoma J Chen, X Ge, W Zhang, P Ding, Y Du, Q Wang, L Li, L Fang, Y Sun, ... Theranostics 10 (7), 3151, 2020 | 44 | 2020 |
Inhibition of complement retards ankylosing spondylitis progression C Yang, P Ding, Q Wang, L Zhang, X Zhang, J Zhao, E Xu, N Wang, ... Scientific reports 6 (1), 34643, 2016 | 42 | 2016 |
Dietary fiber intake and risk of renal cell carcinoma: evidence from a meta-analysis T Huang, P Ding, J Chen, Y Yan, L Zhang, H Liu, P Liu, J Che, J Zheng, ... Medical oncology 31, 1-10, 2014 | 42 | 2014 |
CD59 is a potential biomarker of esophageal squamous cell carcinoma radioresistance by affecting DNA repair Y Zhou, L Chu, Q Wang, W Dai, X Zhang, J Chen, L Li, P Ding, L Zhang, ... Cell Death & Disease 9 (9), 887, 2018 | 36 | 2018 |
Targeting the IRAK1–S100A9 axis overcomes resistance to paclitaxel in nasopharyngeal Carcinoma L Liu, S Liu, P Deng, Y Liang, R Xiao, LQ Tang, J Chen, QY Chen, P Guan, ... Cancer Research 81 (5), 1413-1425, 2021 | 27 | 2021 |
FOXM1c promotes oesophageal cancer metastasis by transcriptionally regulating IRF1 expression Y Zhou, Q Wang, L Chu, W Dai, X Zhang, J Chen, L Zhang, P Ding, ... Cell Proliferation 52 (2), e12553, 2019 | 21 | 2019 |
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer P Deng, Z Wang, J Chen, S Liu, X Yao, S Liu, L Liu, Z Yu, Y Huang, ... The Journal of Clinical Investigation 132 (22), 2022 | 18 | 2022 |
PI3K activation is enhanced by FOXM1D binding to p110 and p85 subunits Q Wang, P Zhang, W Zhang, X Zhang, J Chen, P Ding, L Li, X Lv, L Li, ... Signal Transduction and Targeted Therapy 5 (1), 105, 2020 | 16 | 2020 |
CREBBP cooperates with the cell cycle machinery to attenuate chidamide sensitivity in relapsed/refractory diffuse large B-cell lymphoma Y Sun, Y Gao, J Chen, L Huang, P Deng, J Chen, KXY Chai, JH Hong, ... Cancer Letters 521, 268-280, 2021 | 15 | 2021 |
Targeting enhancer reprogramming to mitigate MEK inhibitor resistance in preclinical models of advanced ovarian cancer S Liu, Q Zou, JP Chen, X Yao, P Guan, W Liang, P Deng, X Lai, J Yin, ... The Journal of Clinical Investigation 131 (20), 2021 | 13 | 2021 |
Midostaurin potentiates rituximab antitumor activity in Burkitt’s lymphoma by inducing apoptosis X Ge, J Chen, L Li, P Ding, Q Wang, W Zhang, L Li, X Lv, D Zhou, Z Jiang, ... Cell death & disease 10 (1), 8, 2018 | 13 | 2018 |
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies JH Hong, CH Yong, HL Heng, JY Chan, MC Lau, J Chen, JY Lee, AH Lim, ... Gut 73 (6), 966-984, 2024 | 11 | 2024 |
EZH2 mediated metabolic rewiring promotes tumor growth independently of histone methyltransferase activity in ovarian cancer J Chen, JH Hong, Y Huang, S Liu, J Yin, P Deng, Y Sun, Z Yu, X Zeng, ... Molecular cancer 22 (1), 85, 2023 | 11 | 2023 |