Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice T Imai, Y Takahashi, M Nishikawa, K Kato, M Morishita, T Yamashita, ... Journal of extracellular vesicles 4 (1), 26238, 2015 | 497 | 2015 |
Exosome-based tumor antigens–adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA M Morishita, Y Takahashi, A Matsumoto, M Nishikawa, Y Takakura Biomaterials 111, 55-65, 2016 | 306 | 2016 |
Quantitative analysis of tissue distribution of the B16BL6-derived exosomes using a streptavidin-lactadherin fusion protein and iodine-125-labeled biotin derivative after … M Morishita, Y Takahashi, M Nishikawa, K Sano, K Kato, T Yamashita, ... Journal of pharmaceutical sciences 104 (2), 705-713, 2015 | 274 | 2015 |
Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics C Charoenviriyakul, Y Takahashi, M Morishita, A Matsumoto, ... European Journal of Pharmaceutical Sciences 96, 316-322, 2017 | 243 | 2017 |
Pharmacokinetics of exosomes—an important factor for elucidating the biological roles of exosomes and for the development of exosome-based therapeutics M Morishita, Y Takahashi, M Nishikawa, Y Takakura Journal of pharmaceutical sciences 106 (9), 2265-2269, 2017 | 195 | 2017 |
Role of phosphatidylserine-derived negative surface charges in the recognition and uptake of intravenously injected B16BL6-derived exosomes by macrophages A Matsumoto, Y Takahashi, M Nishikawa, K Sano, M Morishita, ... Journal of pharmaceutical sciences 106 (1), 168-175, 2017 | 190 | 2017 |
Accelerated growth of B16 BL 6 tumor in mice through efficient uptake of their own exosomes by B16 BL 6 cells A Matsumoto, Y Takahashi, M Nishikawa, K Sano, M Morishita, ... Cancer science 108 (9), 1803-1810, 2017 | 147 | 2017 |
Role of extracellular vesicle surface proteins in the pharmacokinetics of extracellular vesicles C Charoenviriyakul, Y Takahashi, M Morishita, M Nishikawa, Y Takakura Molecular pharmaceutics 15 (3), 1073-1080, 2018 | 93 | 2018 |
Enhanced class I tumor antigen presentation via cytosolic delivery of exosomal cargos by tumor-cell-derived exosomes displaying a pH-sensitive fusogenic peptide M Morishita, Y Takahashi, M Nishikawa, R Ariizumi, Y Takakura Molecular pharmaceutics 14 (11), 4079-4086, 2017 | 71 | 2017 |
Development of spray-freeze-dried siRNA/PEI powder for inhalation with high aerosol performance and strong pulmonary gene silencing activity T Okuda, M Morishita, K Mizutani, A Shibayama, M Okazaki, H Okamoto Journal of Controlled Release 279, 99-113, 2018 | 68 | 2018 |
Characterizing different probiotic-derived extracellular vesicles as a novel adjuvant for immunotherapy M Morishita, M Horita, A Higuchi, M Marui, H Katsumi, A Yamamoto Molecular Pharmaceutics 18 (3), 1080-1092, 2021 | 44 | 2021 |
Improvement of intestinal absorption of curcumin by cyclodextrins and the mechanisms underlying absorption enhancement X Li, S Uehara, K Sawangrat, M Morishita, K Kusamori, H Katsumi, ... International journal of pharmaceutics 535 (1-2), 340-349, 2018 | 44 | 2018 |
Approaches to improve intestinal and transmucosal absorption of peptide and protein drugs A Yamamoto, H Ukai, M Morishita, H Katsumi Pharmacology & Therapeutics 211, 107537, 2020 | 34 | 2020 |
Enhanced intestinal absorption of insulin by Capryol 90, a novel absorption enhancer in rats: implications in oral insulin delivery H Ukai, K Iwasa, T Deguchi, M Morishita, H Katsumi, A Yamamoto Pharmaceutics 12 (5), 462, 2020 | 30 | 2020 |
Bone-targeted drug delivery systems and strategies for treatment of bone metastasis H Katsumi, S Yamashita, M Morishita, A Yamamoto Chemical and Pharmaceutical Bulletin 68 (7), 560-566, 2020 | 29 | 2020 |
Modulation of intestinal transport and absorption of topotecan, a BCRP substrate, by various pharmaceutical excipients and their inhibitory mechanisms of BCRP transporter K Sawangrat, S Yamashita, A Tanaka, M Morishita, K Kusamori, ... Journal of pharmaceutical sciences 108 (3), 1315-1325, 2019 | 29 | 2019 |
l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia … S Matsuura, H Katsumi, H Suzuki, N Hirai, R Takashima, M Morishita, ... Pharmaceutics 10 (4), 251, 2018 | 21 | 2018 |
S-nitrosylated l-serine-modified dendrimer as a kidney-targeting nitric oxide donor for prevention of renal ischaemia/reperfusion injury H Katsumi, R Takashima, H Suzuki, N Hirai, S Matsuura, H Kimura, ... Free radical research 54 (11-12), 841-847, 2020 | 18 | 2020 |
Activation of host immune cells by probiotic-derived extracellular vesicles via TLR2-mediated signaling pathways M Morishita, R Sagayama, Y Yamawaki, M Yamaguchi, H Katsumi, ... Biological and Pharmaceutical Bulletin 45 (3), 354-359, 2022 | 16 | 2022 |
Propylene glycol caprylate as a novel potential absorption enhancer for improving the intestinal absorption of insulin: efficacy, safety, and absorption-enhancing mechanisms H Ukai, A Kawagoe, E Sato, M Morishita, H Katsumi, A Yamamoto Journal of Pharmaceutical Sciences 109 (4), 1483-1492, 2020 | 16 | 2020 |