The role of Gβγ subunits in the organization, assembly, and function of GPCR signaling complexes DJ Dupré, M Robitaille, RV Rebois, TE Hébert Annual review of pharmacology and toxicology 49 (1), 31-56, 2009 | 345 | 2009 |
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (1), 60-68, 2017 | 314 | 2017 |
BioID-based Identification of Skp Cullin F-box (SCF) β-TrCP1/2 E3 Ligase Substrates*[S] E Coyaud, M Mis, EMN Laurent, WH Dunham, AL Couzens, M Robitaille, ... Molecular & Cellular Proteomics 14 (7), 1781-1795, 2015 | 202 | 2015 |
Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking DJ Dupré, M Robitaille, N Éthier, LR Villeneuve, AM Mamarbachi, ... Journal of Biological Chemistry 281 (45), 34561-34573, 2006 | 200 | 2006 |
Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3. 1 channels in living cells RV Rebois, M Robitaille, C Galés, DJ Dupré, A Baragli, P Trieu, N Ethier, ... Journal of cell science 119 (13), 2807-2818, 2006 | 169 | 2006 |
A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression JN Anastas, TL Biechele, M Robitaille, J Muster, KH Allison, S Angers, ... Oncogene 31 (32), 3696-3708, 2012 | 147 | 2012 |
Dopamine receptor-interacting protein 78 acts as a molecular chaperone for Gγ subunits before assembly with Gβ DJ Dupré, M Robitaille, M Richer, N Éthier, AM Mamarbachi, TE Hébert Journal of Biological Chemistry 282 (18), 13703-13715, 2007 | 91 | 2007 |
Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells M Zhang, M Robitaille, AD Showalter, X Huang, Y Liu, A Bhattacharjee, ... Molecular & cellular proteomics 13 (11), 3049-3062, 2014 | 74 | 2014 |
Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells RV Rebois, M Robitaille, D Pétrin, P Zylbergold, P Trieu, TE Hébert Methods 45 (3), 214-218, 2008 | 73 | 2008 |
A single conserved leucine residue on the first intracellular loop regulates eR export of G protein‐coupled receptors MT Duvernay, C Dong, X Zhang, M Robitaille, TE Hébert, G Wu Traffic 10 (5), 552-566, 2009 | 70 | 2009 |
ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses I Azimi, MJG Milevskiy, SB Chalmers, KTDS Yapa, M Robitaille, C Henry, ... Cancers 11 (2), 208, 2019 | 59 | 2019 |
Ubiquitylation and activation of a Rab GTPase is promoted by a β2AR–HACE1 complex V Lachance, J Degrandmaison, S Marois, M Robitaille, S Génier, ... Journal of cell science 127 (1), 111-123, 2014 | 55 | 2014 |
Rab1 GTPase and dimerization in the cell surface expression of angiotensin II type 2 receptor X Zhang, G Wang, DJ Dupre, Y Feng, M Robitaille, E Lazartigues, ... Journal of Pharmacology and Experimental Therapeutics 330 (1), 109-117, 2009 | 49 | 2009 |
A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties Z Pavlovic, JJ Adams, LL Blazer, AK Gakhal, N Jarvik, Z Steinhart, ... MAbs 10 (8), 1157-1167, 2018 | 48 | 2018 |
YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells A Dey, M Robitaille, M Remke, C Maier, A Malhotra, A Gregorieff, ... Oncogene 35 (32), 4256-4268, 2016 | 45 | 2016 |
Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes M Robitaille, N Ramakrishnan, A Baragli, TE Hébert Cellular signalling 21 (4), 488-501, 2009 | 43 | 2009 |
Gβγ is a negative regulator of AP-1 mediated transcription M Robitaille, S Gora, Y Wang, E Goupil, D Pétrin, D Del Duca, ... Cellular signalling 22 (8), 1254-1266, 2010 | 42 | 2010 |
Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability SJ Roy, I Glazkova, L Fréchette, C Iorio-Morin, C Binda, D Pétrin, P Trieu, ... Molecular Endocrinology 27 (8), 1245-1266, 2013 | 39 | 2013 |
SAPCD2 controls spindle orientation and asymmetric divisions by negatively regulating the Gαi-LGN-NuMA ternary complex CWN Chiu, C Monat, M Robitaille, M Lacomme, AM Daulat, G Macleod, ... Developmental cell 36 (1), 50-62, 2016 | 38 | 2016 |
The identification of novel protein-protein interactions in liver that affect glucagon receptor activity J Han, M Zhang, S Froese, FF Dai, M Robitaille, A Bhattacharjee, ... PloS one 10 (6), e0129226, 2015 | 35 | 2015 |