Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor W Deng, J Lee, H Wang, J Miller, A Reik, PD Gregory, A Dean, GA Blobel Cell 149 (6), 1233-1244, 2012 | 828 | 2012 |
Reactivation of developmentally silenced globin genes by forced chromatin looping W Deng, JW Rupon, I Krivega, L Breda, I Motta, KS Jahn, A Reik, ... Cell 158 (4), 849-860, 2014 | 477 | 2014 |
Dynamics of CRISPR-Cas9 genome interrogation in living cells SC Knight, L Xie, W Deng, B Guglielmi, LB Witkowsky, L Bosanac, ... Science 350 (6262), 823-826, 2015 | 389 | 2015 |
An encyclopedia of mouse DNA elements (Mouse ENCODE) Mouse ENCODE Consortium, JA Stamatoyannopoulos, M Snyder, ... Genome biology 13, 1-5, 2012 | 370 | 2012 |
CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells W Deng, X Shi, R Tjian, T Lionnet, RH Singer Proceedings of the National Academy of Sciences 112 (38), 11870-11875, 2015 | 303 | 2015 |
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression Y Cheng, W Wu, SA Kumar, D Yu, W Deng, T Tripic, DC King, KB Chen, ... Genome research 19 (12), 2172-2184, 2009 | 264 | 2009 |
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes JM Lamonica, W Deng, S Kadauke, AE Campbell, R Gamsjaeger, ... Proceedings of the National Academy of Sciences 108 (22), E159-E168, 2011 | 250 | 2011 |
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes T Tripic, W Deng, Y Cheng, Y Zhang, CR Vakoc, GD Gregory, ... Blood, The Journal of the American Society of Hematology 113 (10), 2191-2201, 2009 | 218 | 2009 |
An encyclopedia of mouse DNA elements (Mouse ENCODE) EC Mouse, JA Stamatoyannopoulos, M Snyder, R Hardison, B Ren, ... Genome Biol 13 (8), 418, 2012 | 147 | 2012 |
Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers L Breda, I Motta, S Lourenco, C Gemmo, W Deng, JW Rupon, ... Blood, The Journal of the American Society of Hematology 128 (8), 1139-1143, 2016 | 86 | 2016 |
Do chromatin loops provide epigenetic gene expression states? W Deng, GA Blobel Current opinion in genetics & development 20 (5), 548-554, 2010 | 78 | 2010 |
The P2 capsid protein of the nonenveloped rice dwarf phytoreovirus induces membrane fusion in insect host cells F Zhou, Y Pu, T Wei, H Liu, W Deng, C Wei, B Ding, T Omura, Y Li Proceedings of the National Academy of Sciences 104 (49), 19547-19552, 2007 | 60 | 2007 |
Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8 F Zhou, G Wu, W Deng, Y Pu, C Wei, Y Li FEBS letters 581 (1), 34-40, 2007 | 35 | 2007 |
Manipulating nuclear architecture W Deng, GA Blobel Current opinion in genetics & development 25, 1-7, 2014 | 29 | 2014 |
The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors H Wang, B Li, L Zuo, B Wang, Y Yan, K Tian, R Zhou, C Wang, X Chen, ... Nature communications 13 (1), 5703, 2022 | 17 | 2022 |
Dynamic transcription regulation at the single-molecule level Z Wang, W Deng Dev Biol, 67-81, 2022 | 12 | 2022 |
Detecting Long-Range Enhancer–Promoter Interactions by Quantitative Chromosome Conformation Capture W Deng, GA Blobel Enhancer RNAs: Methods and Protocols, 51-62, 2017 | 12 | 2017 |
Viral vectors for prophylaxis and therapy of hemoglobinopathies S Rivella, L Breda, D Alisa, G Blobel, W Deng US Patent 11,311,632, 2022 | 3 | 2022 |
Using forced chromatin looping to overcome developmental silencing of embryonic and fetal β-type globin genes in adult erythroid cells JW Rupon, W Deng, H Wang, PD Gregory, A Reik, A Dean, GA Blobel Blood 122 (21), 433, 2013 | 3 | 2013 |
Controlled gene expression methods G Blobel, W Deng US Patent 9,815,877, 2017 | 1 | 2017 |