关注
Scott Pesiridis
Scott Pesiridis
Scientific Director, GSK
在 gsk.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
DNA sensing by the cGAS–STING pathway in health and disease
M Motwani, S Pesiridis, KA Fitzgerald
Nature Reviews Genetics 20 (11), 657-674, 2019
9292019
Design of amidobenzimidazole STING receptor agonists with systemic activity
JM Ramanjulu, GS Pesiridis, J Yang, N Concha, R Singhaus, SY Zhang, ...
Nature 564 (7736), 439-443, 2018
5472018
The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins
WJ Friesen, S Paushkin, A Wyce, S Massenet, GS Pesiridis, G Van Duyne, ...
Molecular and cellular biology 21 (24), 8289-8300, 2001
5012001
Succination inactivates gasdermin D and blocks pyroptosis
F Humphries, L Shmuel-Galia, N Ketelut-Carneiro, S Li, B Wang, ...
Science 369 (6511), 1633-1637, 2020
3812020
Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
GS Pesiridis, VMY Lee, JQ Trojanowski
Human molecular genetics 18 (R2), R156-R162, 2009
3682009
A “two-hit” hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport
GS Pesiridis, K Tripathy, S Tanik, JQ Trojanowski, VMY Lee
Journal of Biological Chemistry 286 (21), 18845-18855, 2011
1352011
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection
F Humphries, L Shmuel-Galia, Z Jiang, R Wilson, P Landis, SL Ng, ...
Science Immunology 6 (59), eabi9002, 2021
1012021
Role of pICLn in methylation of Sm proteins by PRMT5
GS Pesiridis, E Diamond, GD Van Duyne
Journal of biological chemistry 284 (32), 21347-21359, 2009
1012009
Discovery of GSK8612, a highly selective and potent TBK1 inhibitor
DW Thomson, D Poeckel, N Zinn, C Rau, K Strohmer, AJ Wagner, ...
ACS medicinal chemistry letters 10 (5), 780-785, 2019
602019
Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication
M Triantafilou, J Ramanjulu, LM Booty, G Jimenez-Duran, H Keles, ...
Nature Communications 13 (1), 1406, 2022
182022
Preclinical characterization of GSK532, a novel STING agonist with potent anti-tumor activity
J Yang, M Adam, J Clemens, K Creech, J Schneck, K Pasikanti, JL Tran, ...
Cancer Research 78 (13_Supplement), 5554-5554, 2018
132018
Targeting STING oligomerization with small-molecule inhibitors
F Humphries, L Shmuel-Galia, Z Jiang, JY Zhou, L Barasa, S Mondal, ...
Proceedings of the National Academy of Sciences 120 (33), e2305420120, 2023
102023
Author correction: design of amidobenzimidazole STING receptor agonists with systemic activity
JM Ramanjulu, GS Pesiridis, J Yang, N Concha, R Singhaus, SY Zhang, ...
Nature 570 (7761), E53-E53, 2019
62019
Modulators of stimulator of interferon genes (sting)
DT Fosbenner, TL Graybill, J Kang, BW King, LAN Yunfeng, LK Leister, ...
US Patent 11,377,440, 2022
52022
Characterization of the Staphylococcus aureus Sortase Transpeptidase: A Novel Target for the Development of Chemotherapeutics Against Gram-Positive Bacteria
R Kruger, S Pesiridis, DG McCafferty
Peptides: The Wave of the Future: Proceedings of the Second International …, 2001
22001
Methods for Administering STING Agonists
GS Pesiridis, T Jean-Luc, Y Jingsong, JM Ramanjulu
US Patent App. 16/753,365, 2020
2020
Design of amidobenzimidazole STING receptor agonists with systemic activity (vol 564, pg 439, 2018)
JM Ramanjulu, GS Pesiridis, JS Yang, N Concha, R Singhaus, SY Zhang, ...
Nature 570 (7761), E53-E53, 2019
2019
Function of pICln in regulating PRMT5 activity through the combined interaction of the pICln-SmD3 complex
GS Pesiridis
University of Pennsylvania, 2006
2006
Volume 18 Review Issue 2 15 October 2009
GS Pesiridis, VMY Lee, JQ Trojanowski
系统目前无法执行此操作,请稍后再试。
文章 1–19