| Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse T Stylianopoulos, JD Martin, M Snuderl, F Mpekris, SR Jain, RK Jain Cancer research 73 (13), 3833-3841, 2013 | 457 | 2013 |
| Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma Y Zhao, J Cao, A Melamed, M Worley, A Gockley, D Jones, HT Nia, ... Proceedings of the National Academy of Sciences 116 (6), 2210-2219, 2019 | 209 | 2019 |
| Combining microenvironment normalization strategies to improve cancer immunotherapy F Mpekris, C Voutouri, JW Baish, DG Duda, LL Munn, T Stylianopoulos, ... Proceedings of the National Academy of Sciences 117 (7), 3728-3737, 2020 | 196 | 2020 |
| Role of vascular normalization in benefit from metronomic chemotherapy F Mpekris, JW Baish, T Stylianopoulos, RK Jain Proceedings of the National Academy of Sciences 114 (8), 1994-1999, 2017 | 163 | 2017 |
| Pirfenidone normalizes the tumor microenvironment to improve chemotherapy C Polydorou, F Mpekris, P Papageorgis, C Voutouri, T Stylianopoulos Oncotarget 8 (15), 24506, 2017 | 159 | 2017 |
| TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity M Panagi, C Voutouri, F Mpekris, P Papageorgis, MR Martin, JD Martin, ... Theranostics 10 (4), 1910, 2020 | 140 | 2020 |
| Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors C Voutouri, F Mpekris, P Papageorgis, AD Odysseos, T Stylianopoulos PloS one 9 (8), e104717, 2014 | 122 | 2014 |
| Dexamethasone increases cisplatin-loaded nanocarrier delivery and efficacy in metastatic breast cancer by normalizing the tumor microenvironment JD Martin, M Panagi, C Wang, TT Khan, MR Martin, C Voutouri, K Toh, ... ACS nano 13 (6), 6396-6408, 2019 | 109 | 2019 |
| Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo-and nanotherapeutics in a size-independent manner P Papageorgis, C Polydorou, F Mpekris, C Voutouri, E Agathokleous, ... Scientific reports 7 (1), 46140, 2017 | 107 | 2017 |
| Stress-mediated progression of solid tumors: effect of mechanical stress on tissue oxygenation, cancer cell proliferation, and drug delivery F Mpekris, S Angeli, AP Pirentis, T Stylianopoulos Biomechanics and modeling in mechanobiology 14, 1391-1402, 2015 | 96 | 2015 |
| Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies C Voutouri, ND Kirkpatrick, E Chung, F Mpekris, JW Baish, LL Munn, ... Proceedings of the National Academy of Sciences 116 (7), 2662-2671, 2019 | 85 | 2019 |
| Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo-and nanotherapy F Mpekris, P Papageorgis, C Polydorou, C Voutouri, M Kalli, AP Pirentis, ... Journal of Controlled Release 261, 105-112, 2017 | 81 | 2017 |
| Normalizing the microenvironment overcomes vessel compression and resistance to nano‐immunotherapy in breast cancer lung metastasis F Mpekris, M Panagi, C Voutouri, JD Martin, R Samuel, S Takahashi, ... Advanced Science 8 (3), 2001917, 2021 | 73 | 2021 |
| Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models M Panagi, F Mpekris, P Chen, C Voutouri, Y Nakagawa, JD Martin, T Hiroi, ... Nature Communications 13 (1), 7165, 2022 | 47 | 2022 |
| NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression C Demetriadou, D Pavlou, F Mpekris, C Achilleos, T Stylianopoulos, ... Cell death & disease 10 (3), 236, 2019 | 45 | 2019 |
| Activin A signaling regulates IL13Rα2 expression to promote breast cancer metastasis M Kalli, F Mpekris, CK Wong, M Panagi, S Ozturk, S Thiagalingam, ... Frontiers in Oncology 9, 32, 2019 | 42 | 2019 |
| Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy F Mpekris, C Voutouri, M Panagi, JW Baish, RK Jain, T Stylianopoulos Journal of Controlled Release 345, 190-199, 2022 | 36 | 2022 |
| Endothelin inhibition potentiates cancer immunotherapy revealing mechanical biomarkers predictive of response C Voutouri, M Panagi, F Mpekris, A Stylianou, C Michael, MA Averkiou, ... Advanced Therapeutics 4 (9), 2000289, 2021 | 22 | 2021 |
| Magnetoresponsive polymer networks as adsorbents for the removal of U (VI) ions from aqueous media R Ilia, I Liatsou, I Savva, E Vasile, L Vekas, O Marinica, F Mpekris, ... European Polymer Journal 97, 138-146, 2017 | 22 | 2017 |
| Remodeling of extracellular matrix due to solid stress accumulation during tumor growth AP Pirentis, C Polydorou, P Papageorgis, C Voutouri, F Mpekris, ... Connective tissue research 56 (5), 345-354, 2015 | 22 | 2015 |
Triantafyllos StylianopoulosAssociate Professor of Mechanical Engineering, Cancer Biophysics Lab, University of Cyprus在 ucy.ac.cy 的电子邮件经过验证
