Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study M Van Zuiden, E Geuze, HLDM Willemen, E Vermetten, M Maas, ... Biological psychiatry 71 (4), 309-316, 2012 | 224 | 2012 |
Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke CTJ Van Velthoven, RA Sheldon, A Kavelaars, N Derugin, ZS Vexler, ... Stroke 44 (5), 1426-1432, 2013 | 212 | 2013 |
Pre-existing high glucocorticoid receptor number predicting development of posttraumatic stress symptoms after military deployment M Van Zuiden, E Geuze, HLDM Willemen, E Vermetten, M Maas, ... American Journal of Psychiatry 168 (1), 89-96, 2011 | 202 | 2011 |
MicroRNA-124 as a novel treatment for persistent hyperalgesia HLDM Willemen, XJ Huo, QL Mao-Ying, J Zijlstra, CJ Heijnen, ... Journal of neuroinflammation 9, 1-10, 2012 | 183 | 2012 |
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15. 2 region MJ Peters, L Broer, HLDM Willemen, G Eiriksdottir, LJ Hocking, ... Annals of the rheumatic diseases 72 (3), 427-436, 2013 | 144 | 2013 |
GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain N Eijkelkamp, CJ Heijnen, HLDM Willemen, R Deumens, EAJ Joosten, ... Journal of Neuroscience 30 (6), 2138-2149, 2010 | 124 | 2010 |
Identification of the missing links in prokaryotic pentose oxidation pathways: evidence for enzyme recruitment SJJ Brouns, J Walther, APL Snijders, HJG van de Werken, ... Journal of Biological Chemistry 281 (37), 27378-27388, 2006 | 124 | 2006 |
Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain M van der Vlist, R Raoof, HLDM Willemen, J Prado, S Versteeg, CM Gil, ... Neuron 110 (4), 613-626. e9, 2022 | 123* | 2022 |
Divergent roles of immune cells and their mediators in pain R Raoof, HLDM Willemen, N Eijkelkamp Rheumatology 57 (3), 429-440, 2018 | 121 | 2018 |
Monocytes/Macrophages control resolution of transient inflammatory pain HLDM Willemen, N Eijkelkamp, AG Carbajal, H Wang, M Mack, J Zijlstra, ... The Journal of Pain 15 (5), 496-506, 2014 | 112 | 2014 |
Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cε, and MEK/ERK N Eijkelkamp, H Wang, A Garza-Carbajal, HLDM Willemen, FJ Zwartkruis, ... Journal of Neuroscience 30 (38), 12806-12815, 2010 | 107 | 2010 |
Microglial/macrophage GRK2 determines duration of peripheral IL-1β-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling HLDM Willemen, N Eijkelkamp, H Wang, R Dantzer, GW Dorn II, ... Pain 150 (3), 550-560, 2010 | 107 | 2010 |
Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain H Wang, CJ Heijnen, CTJ Van Velthoven, HLDM Willemen, Y Ishikawa, ... The Journal of clinical investigation 123 (12), 5023-5034, 2013 | 103 | 2013 |
IL4-10 fusion protein is a novel drug to treat persistent inflammatory pain N Eijkelkamp, C Steen-Louws, SAY Hartgring, HLDM Willemen, J Prado, ... Journal of Neuroscience 36 (28), 7353-7363, 2016 | 83 | 2016 |
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes E Davydova, T Shimazu, MK Schuhmacher, ME Jakobsson, ... Nature communications 12 (1), 891, 2021 | 71 | 2021 |
Stimulation of β2-adrenergic receptors inhibits calcineurin activity in CD4+ T cells via PKA–AKAP interaction C Riether, A Kavelaars, T Wirth, G Pacheco-López, R Doenlen, ... Brain, behavior, and immunity 25 (1), 59-66, 2011 | 68 | 2011 |
Therapeutic potential of genetically modified mesenchymal stem cells after neonatal hypoxic-ischemic brain damage CT Van Velthoven, L Braccioli, HLDM Willemen, A Kavelaars, CJ Heijnen Molecular Therapy 22 (3), 645-654, 2014 | 64 | 2014 |
Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2 R Vila-Bedmar, M Cruces-Sande, E Lucas, HLDM Willemen, CJ Heijnen, ... Science signaling 8 (386), ra73-ra73, 2015 | 63 | 2015 |
Cell-specific roles of GRK2 in onset and severity of hypoxic-ischemic brain damage in neonatal mice CH Nijboer, CJ Heijnen, HLDM Willemen, F Groenendaal, GW Dorn II, ... Brain, behavior, and immunity 24 (3), 420-426, 2010 | 33 | 2010 |
Microglial GRK2: a novel regulator of transition from acute to chronic pain A Kavelaars, N Eijkelkamp, HLDM Willemen, H Wang, AG Carbajal, ... Brain, behavior, and immunity 25 (6), 1055-1060, 2011 | 32 | 2011 |