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Musleh Muthana
Musleh Muthana
Postdoctoral Fellow, Institute of Human Virology, University of Maryland School of Medicine
在 ucdavis.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Highly efficient chemoenzymatic synthesis of β1–4-linked galactosides with promiscuous bacterial β1–4-galactosyltransferases
K Lau, V Thon, H Yu, L Ding, Y Chen, MM Muthana, D Wong, R Huang, ...
Chemical communications 46 (33), 6066-6068, 2010
1942010
Efficient one-pot multienzyme synthesis of UDP-sugars using a promiscuous UDP-sugar pyrophosphorylase from Bifidobacterium longum (BLUSP)
MM Muthana, J Qu, Y Li, L Zhang, H Yu, L Ding, H Malekan, X Chen
Chemical communications 48 (21), 2728-2730, 2012
1312012
Donor substrate promiscuity of bacterial β1–3-N-acetylglucosaminyltransferases and acceptor substrate flexibility of β1–4-galactosyltransferases
Y Li, M Xue, X Sheng, H Yu, J Zeng, V Thon, Y Chen, MM Muthana, ...
Bioorganic & medicinal chemistry 24 (8), 1696-1705, 2016
562016
Probe sialidase substrate specificity using chemoenzymatically synthesized sialosides containing C9-modified sialic acid
Z Khedri, MM Muthana, Y Li, SM Muthana, H Yu, H Cao, X Chen
Chemical communications 48 (27), 3357-3359, 2012
512012
Improved one-pot multienzyme (OPME) systems for synthesizing UDP-uronic acids and glucuronides
MM Muthana, J Qu, M Xue, T Klyuchnik, A Siu, Y Li, L Zhang, H Yu, L Li, ...
Chemical Communications 51 (22), 4595-4598, 2015
482015
Substrate specificity provides insights into the sugar donor recognition mechanism of O-GlcNAc transferase (OGT)
X Ma, P Liu, H Yan, H Sun, X Liu, F Zhou, L Li, Y Chen, MM Muthana, ...
PloS one 8 (5), e63452, 2013
422013
Systematic chemoenzymatic synthesis of O-sulfated sialyl Lewis x antigens
A Santra, H Yu, N Tasnima, MM Muthana, Y Li, J Zeng, NJ Kenyon, ...
Chemical science 7 (4), 2827-2831, 2016
372016
Chemoenzymatic synthesis of sialosides containing C7-modified sialic acids and their application in sialidase substrate specificity studies
Z Khedri, Y Li, S Muthana, MM Muthana, CW Hsiao, H Yu, X Chen
Carbohydrate research 389, 100-111, 2014
362014
Synthesis of selective inhibitors against V. cholerae sialidase and human cytosolic sialidase NEU2
Z Khedri, Y Li, H Cao, J Qu, H Yu, MM Muthana, X Chen
Organic & biomolecular chemistry 10 (30), 6112-6120, 2012
332012
Donor substrate promiscuity of the N-acetylglucosaminyltransferase activities of Pasteurella multocida heparosan synthase 2 (PmHS2) and Escherichia coli K5 KfiA
Y Li, H Yu, V Thon, Y Chen, MM Muthana, J Qu, L Hie, X Chen
Applied microbiology and biotechnology 98, 1127-1134, 2014
302014
Site-specific chemoenzymatic conjugation of high-affinity M6P glycan ligands to antibodies for targeted protein degradation
X Zhang, H Liu, J He, C Ou, TC Donahue, MM Muthana, L Su, LX Wang
ACS chemical biology 17 (11), 3013-3023, 2022
262022
9-Azido-9-deoxy-2, 3-difluorosialic acid as a subnanomolar inhibitor against bacterial sialidases
W Li, A Santra, H Yu, TJ Slack, MM Muthana, D Shi, Y Liu, X Chen
The Journal of organic chemistry 84 (11), 6697-6708, 2019
182019
Characterizing non-hydrolyzing Neisseria meningitidis serogroup A UDP-N-acetylglucosamine (UDP-GlcNAc) 2-epimerase using UDP-N-acetylmannosamine (UDP-ManNAc) and derivatives
L Zhang, MM Muthana, H Yu, JB McArthur, J Qu, X Chen
Carbohydrate research 419, 18-28, 2016
142016
S-15 in combination of Akt inhibitor promotes the expansion of CD45RACCR7+ tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1+Tim-3 …
B Xu, L Yuan, G Chen, T Li, J Zhou, C Zhang, P Qin, MM Muthana, ...
Cancer Cell International 19, 1-11, 2019
52019
Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4–and PD-1–targeted immunotherapy
M Liu, X Wang, X Du, W Wu, Y Zhang, P Zhang, C Ai, M Devenport, J Su, ...
Science translational medicine 15 (685), eabm5663, 2023
42023
Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA
OE Martinez, BJ Mahoney, AK Goring, SW Yi, DP Tran, D Cascio, ...
Journal of Biological Chemistry 298 (2), 2022
42022
CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment
MM Muthana, X Du, M Liu, X Wang, W Wu, C Ai, L Su, P Zheng, Y Liu
Elife 12, RP87281, 2023
22023
Chemoenzymatic synthesis of heparin and heparan sulfate analogs
X Chen, H Yu, Y Li, Y Chen, J Qu, MM Muthana, K Lau, L Bode
US Patent 10,160,986, 2018
22018
Chemoenzymatic synthesis of heparin and heparan sulfate analogs
X Chen, H Yu, K Lau, L Bode
US Patent 9,290,530, 2016
22016
One-Pot Chemoenzymatic Synthesis of UDP-Sugars and Sulfated Glycans
MM Muthana
University of California, Davis, 2015
2015
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