Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability J Sollier, CT Stork, ML García-Rubio, RD Paulsen, A Aguilera, ... Molecular cell 56 (6), 777-785, 2014 | 610 | 2014 |
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2 V Bhatia, SI Barroso, ML García-Rubio, E Tumini, E Herrera-Moyano, ... Nature 511 (7509), 362-365, 2014 | 552 | 2014 |
The Fanconi anemia pathway protects genome integrity from R-loops ML García-Rubio, C Pérez-Calero, SI Barroso, E Tumini, ... PLoS genetics 11 (11), e1005674, 2015 | 310 | 2015 |
Genome‐wide function of THO/TREX in active genes prevents R‐loop‐dependent replication obstacles B Gómez‐González, M García‐Rubio, R Bermejo, H Gaillard, K Shirahige, ... The EMBO journal 30 (15), 3106-3119, 2011 | 261 | 2011 |
The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription–replication conflicts E Herrera-Moyano, X Mergui, ML García-Rubio, S Barroso, A Aguilera Genes & development 28 (7), 735-748, 2014 | 213 | 2014 |
FANCD2 facilitates replication through common fragile sites A Madireddy, ST Kosiyatrakul, RA Boisvert, E Herrera-Moyano, ... Molecular cell 64 (2), 388-404, 2016 | 186 | 2016 |
Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes B Palancade, X Liu, M Garcia-Rubio, A Aguilera, X Zhao, V Doye Molecular biology of the cell 18 (8), 2912-2923, 2007 | 162 | 2007 |
Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation AG Rondón, S Jimeno, M García-Rubio, A Aguilera Journal of Biological Chemistry 278 (40), 39037-39043, 2003 | 161 | 2003 |
Hpr1 Is Preferentially Required for Transcription of Either Long or G+C-Rich DNA Sequences in Saccharomyces cerevisiae S Chávez, M Garcı́a-Rubio, F Prado, A Aguilera Molecular and cellular biology 21 (20), 7054-7064, 2001 | 150 | 2001 |
Interdependence between transcription and mRNP processing and export, and its impact on genetic stability R Luna, S Jimeno, M Marín, P Huertas, M García-Rubio, A Aguilera Molecular cell 18 (6), 711-722, 2005 | 141 | 2005 |
Histone mutants separate R loop formation from genome instability induction D García-Pichardo, JC Cañas, ML García-Rubio, B Gómez-González, ... Molecular cell 66 (5), 597-609. e5, 2017 | 132 | 2017 |
Molecular evidence for a positive role of Spt4 in transcription elongation AG Rondón, M García‐Rubio, S González‐Barrera, A Aguilera The EMBO journal, 2003 | 130 | 2003 |
Molecular evidence indicating that the yeast PAF complex is required for transcription elongation AG Rondón, M Gallardo, M García‐Rubio, A Aguilera EMBO reports 5 (1), 47-53, 2004 | 128 | 2004 |
The Npl3 hnRNP prevents R-loop-mediated transcription–replication conflicts and genome instability JM Santos-Pereira, AB Herrero, ML García-Rubio, A Marín, S Moreno, ... Genes & development 27 (22), 2445-2458, 2013 | 111 | 2013 |
Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair H Gaillard, C Tous, J Botet, C González-Aguilera, MJ Quintero, ... PLoS genetics 5 (2), e1000364, 2009 | 109 | 2009 |
Coordinated control of replication and transcription by a SAPK protects genomic integrity A Duch, I Felipe-Abrio, S Barroso, G Yaakov, M García-Rubio, A Aguilera, ... Nature 493 (7430), 116-119, 2013 | 95 | 2013 |
The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins S Barroso, E Herrera‐Moyano, S Muñoz, M García‐Rubio, ... EMBO reports 20 (9), e47250, 2019 | 88 | 2019 |
The stress-activated protein kinase Hog1 mediates S phase delay in response to osmostress G Yaakov, A Duch, M García-Rubio, J Clotet, J Jimenez, A Aguilera, ... Molecular biology of the cell 20 (15), 3572-3582, 2009 | 83 | 2009 |
Yra1-bound RNA–DNA hybrids cause orientation-independent transcription–replication collisions and telomere instability M García-Rubio, P Aguilera, J Lafuente-Barquero, JF Ruiz, MN Simon, ... Genes & development 32 (13-14), 965-977, 2018 | 82 | 2018 |
Transcription and Double-Strand Breaks Induce Similar Mitotic Recombination Events in Saccharomyces cerevisiae S González-Barrera, M García-Rubio, A Aguilera Genetics 162 (2), 603-614, 2002 | 76 | 2002 |