Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding BC Mounce, T Cesaro, L Carrau, T Vallet, M Vignuzzi Antiviral research 142, 148-157, 2017 | 370 | 2017 |
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 192 | 2021 |
ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53 VE Ghouzzi, FT Bianchi, I Molineris, BC Mounce, GE Berto, M Rak, ... Cell death & disease 7 (10), e2440-e2440, 2016 | 125 | 2016 |
Whole-genome sequencing analysis from the chikungunya virus Caribbean outbreak reveals novel evolutionary genomic elements KA Stapleford, G Moratorio, R Henningsson, R Chen, S Matheus, ... PLoS neglected tropical diseases 10 (1), e0004402, 2016 | 124 | 2016 |
Interferon-induced spermidine-spermine acetyltransferase and polyamine depletion restrict Zika and chikungunya viruses BC Mounce, EZ Poirier, G Passoni, E Simon-Loriere, T Cesaro, M Prot, ... Cell host & microbe 20 (2), 167-177, 2016 | 121 | 2016 |
Polyamines and their role in virus infection BC Mounce, ME Olsen, M Vignuzzi, JH Connor Microbiology and Molecular Biology Reviews 81 (4), 10.1128/mmbr. 00029-17, 2017 | 106 | 2017 |
Inhibition of polyamine biosynthesis is a broad-spectrum strategy against RNA viruses BC Mounce, T Cesaro, G Moratorio, PJ Hooikaas, A Yakovleva, ... Journal of virology 90 (21), 9683-9692, 2016 | 92 | 2016 |
Attenuation of RNA viruses by redirecting their evolution in sequence space G Moratorio, R Henningsson, C Barbezange, L Carrau, AV Bordería, ... Nature microbiology 2 (8), 1-12, 2017 | 80 | 2017 |
Diverse functions of polyamines in virus infection MR Firpo, BC Mounce Biomolecules 10 (4), 628, 2020 | 66 | 2020 |
Low-fidelity polymerases of alphaviruses recombine at higher rates to overproduce defective interfering particles EZ Poirier, BC Mounce, K Rozen-Gagnon, PJ Hooikaas, KA Stapleford, ... Journal of virology 90 (5), 2446-2454, 2016 | 65 | 2016 |
Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes G Passoni, C Langevin, N Palha, BC Mounce, V Briolat, P Affaticati, ... Disease models & mechanisms 10 (7), 847-857, 2017 | 60 | 2017 |
Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells WP Mboko, BC Mounce, J Emmer, E Darrah, SB Patel, VL Tarakanova Journal of virology 88 (12), 6993-7004, 2014 | 57 | 2014 |
Chikungunya virus overcomes polyamine depletion by mutation of nsP1 and the opal stop codon to confer enhanced replication and fitness BC Mounce, T Cesaro, L Vlajnić, A Vidiņa, T Vallet, J Weger-Lucarelli, ... Journal of virology 91 (15), 10.1128/jvi. 00344-17, 2017 | 47 | 2017 |
Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro N Drayman, KA Jones, SA Azizi, HM Froggatt, K Tan, NI Maltseva, S Chen, ... BioRxiv, 2020.08. 31.274639, 2020 | 43 | 2020 |
Coordinate regulation of DNA damage and type I interferon responses imposes an antiviral state that attenuates mouse gammaherpesvirus type 68 replication in primary macrophages WP Mboko, BC Mounce, BM Wood, JM Kulinski, JA Corbett, ... Journal of virology 86 (12), 6899-6912, 2012 | 38 | 2012 |
Targeting polyamines inhibits coronavirus infection by reducing cellular attachment and entry MR Firpo, V Mastrodomenico, GM Hawkins, M Prot, L Levillayer, ... ACS infectious diseases 7 (6), 1423-1432, 2020 | 37 | 2020 |
Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection JM Kulinski, SM Leonardo, BC Mounce, L Malherbe, SB Gauld, ... Journal of virology 86 (23), 12826-12837, 2012 | 37 | 2012 |
Novel ionophores active against La Crosse virus identified through rapid antiviral screening ZJ Sandler, MR Firpo, OS Omoba, MN Vu, VD Menachery, BC Mounce Antimicrobial agents and chemotherapy 64 (6), 10.1128/aac. 00086-20, 2020 | 36 | 2020 |
Ribavirin induces polyamine depletion via nucleotide depletion to limit virus replication PM Tate, V Mastrodomenico, BC Mounce Cell reports 28 (10), 2620-2633. e4, 2019 | 31 | 2019 |
Coxsackievirus B3 responds to polyamine depletion via enhancement of 2A and 3C protease activity CN Dial, PM Tate, TM Kicmal, BC Mounce Viruses 11 (5), 403, 2019 | 30 | 2019 |