Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on … BT Navé, DM Ouwens, DJ Withers, DR Alessi, PR SHEPHERD Biochemical Journal 344 (2), 427-431, 1999 | 1226 | 1999 |
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome D Lamers, S Famulla, N Wronkowitz, S Hartwig, S Lehr, DM Ouwens, ... Diabetes 60 (7), 1917-1925, 2011 | 682 | 2011 |
Novel insights into glucocorticoid‐mediated diabetogenic effects: towards expansion of therapeutic options? DH Van Raalte, DM Ouwens, M Diamant European journal of clinical investigation 39 (2), 81-93, 2009 | 538 | 2009 |
Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats DM Ouwens, C Boer, M Fodor, P De Galan, RJ Heine, JA Maassen, ... Diabetologia 48, 1229-1237, 2005 | 314 | 2005 |
The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease DM Ouwens, H Sell, S Greulich, J Eckel Journal of cellular and molecular medicine 14 (9), 2223-2234, 2010 | 288 | 2010 |
Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras–MEK–ERK pathway and of Thr69 through RalGDS–Src–p38 DM Ouwens, ND de Ruiter, GCM van der Zon, AP Carter, J Schouten, ... The EMBO journal 21 (14), 3782-3793, 2002 | 284 | 2002 |
Identification and validation of novel adipokines released from primary human adipocytes S Lehr, S Hartwig, D Lamers, S Famulla, S Müller, FG Hanisch, C Cuvelier, ... Molecular & cellular proteomics 11 (1), 2012 | 283 | 2012 |
Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification DM Ouwens, M Diamant, M Fodor, DDJ Habets, M Pelsers, ... Diabetologia 50, 1938-1948, 2007 | 266 | 2007 |
CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice JR Goudriaan, VEH Dahlmans, B Teusink, DM Ouwens, M Febbraio, ... Journal of lipid research 44 (12), 2270-2277, 2003 | 234 | 2003 |
Role of PRAS40 in Akt and mTOR signaling in health and disease C Wiza, EBM Nascimento, DM Ouwens American Journal of Physiology-Endocrinology And Metabolism 302 (12), E1453-60, 2012 | 211 | 2012 |
Anti‐inflammatory cytokines and risk of type 2 diabetes C Herder, M Carstensen, DM Ouwens Diabetes, Obesity and Metabolism 15 (s3), 39-50, 2013 | 209 | 2013 |
Secretory products from epicardial adipose tissue of patients with type 2 diabetes mellitus induce cardiomyocyte dysfunction S Greulich, B Maxhera, G Vandenplas, DH de Wiza, K Smiris, H Mueller, ... Circulation 126 (19), 2324-2334, 2012 | 198 | 2012 |
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease L Verschuren, T Kooistra, J Bernhagen, PJ Voshol, DM Ouwens, ... Circulation research 105 (1), 99-107, 2009 | 193 | 2009 |
Secretome profiling of primary human skeletal muscle cells S Hartwig, S Raschke, B Knebel, M Scheler, M Irmler, W Passlack, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (5), 1011-1017, 2014 | 172 | 2014 |
Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans DH Van Raalte, RE Van Genugten, MML Linssen, DM Ouwens, ... Diabetes Care 34 (2), 412-417, 2011 | 162 | 2011 |
Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation AM Van Den Hoek, C van Heijningen, JP Schroder-van der Elst, ... Diabetes 57 (9), 2304-2310, 2008 | 158 | 2008 |
Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography CE van den Brom, MC Huisman, R Vlasblom, NM Boontje, S Duijst, ... Cardiovascular diabetology 8, 1-12, 2009 | 149 | 2009 |
Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice PJ Voshol, G Haemmerle, DM Ouwens, R Zimmermann, R Zechner, ... Endocrinology 144 (8), 3456-3462, 2003 | 141 | 2003 |
Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies S Greulich, WJY Chen, B Maxhera, LJ Rijzewijk, RW van der Meer, ... PloS one 8 (3), e59697, 2013 | 130 | 2013 |
Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin CH Wiegman, RHJ Bandsma, M Ouwens, FH van der Sluijs, R Havinga, ... Diabetes 52 (5), 1081-1089, 2003 | 129 | 2003 |