TRAIP is a master regulator of DNA interstrand crosslink repair RA Wu, DR Semlow, AN Kamimae-Lanning, OV Kochenova, G Chistol, ... Nature 567 (7747), 267-272, 2019 | 169 | 2019 |
The genetic and biochemical basis of FANCD2 monoubiquitination E Rajendra, VH Oestergaard, F Langevin, M Wang, GL Dornan, KJ Patel, ... Molecular cell 54 (5), 858-869, 2014 | 132 | 2014 |
Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID M Wang, C Rada, MS Neuberger Journal of Experimental Medicine 207 (1), 141-153, 2010 | 128 | 2010 |
Two aldehyde clearance systems are essential to prevent lethal formaldehyde accumulation in mice and humans FA Dingler, M Wang, A Mu, CL Millington, N Oberbeck, S Watcham, ... Molecular cell 80 (6), 996-1012. e9, 2020 | 115 | 2020 |
AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity M Wang, Z Yang, C Rada, MS Neuberger Nature structural & molecular biology 16 (7), 769-776, 2009 | 107 | 2009 |
Autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation: analysis of 533 adult patients who underwent transplantation at King's College Hospital M Wang, W Wang, A Abeywardane, M Adikarama, D McLornan, K Raj, ... Biology of Blood and Marrow Transplantation 21 (1), 60-66, 2015 | 85 | 2015 |
Targeting protein neddylation: a novel therapeutic strategy for the treatment of cancer M Wang, BC Medeiros, HP Erba, DJ DeAngelo, FJ Giles, RT Swords Expert opinion on therapeutic targets 15 (3), 253-264, 2011 | 80 | 2011 |
A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation K Kollmann, W Warsch, C Gonzalez-Arias, FL Nice, E Avezov, J Milburn, ... Leukemia 31 (4), 934-944, 2017 | 62 | 2017 |
Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma U Eskiocak, V Ramesh, JG Gill, Z Zhao, SW Yuan, M Wang, T Vandergriff, ... Nature communications 7 (1), 1-19, 2016 | 57 | 2016 |
Genotoxic aldehydes in the hematopoietic system M Wang, FA Dingler, KJ Patel Blood, The Journal of the American Society of Hematology 139 (14), 2119-2129, 2022 | 28 | 2022 |
Mutants of activation-induced cytidine deaminase (AID) and methods of use M Wang, Z Yang, C Rada, M Neuberger US Patent 9,683,226, 2017 | 16 | 2017 |
Analysis of BCR–ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype H Grant, X Jiang, J Stebbing, L Foroni, C Craddock, M Griffiths, RE Clark, ... Leukemia 24 (10), 1817-1821, 2010 | 11 | 2010 |
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner M Wang, LTL Brandt, X Wang, H Russell, E Mitchell, ... Molecular Cell, 2023 | 8 | 2023 |
A histone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production N Wit, E Gogola, JA West, T Vornbäumen, RV Seear, PSJ Bailey, ... Science Advances 9 (20), eadg2235, 2023 | 8 | 2023 |
A high-throughput assay for DNA deaminases M Wang, C Rada, MS Neuberger RNA and DNA Editing, 171-184, 2011 | 7 | 2011 |
Characterization of innate immune viral sensors in patients following allogeneic hematopoietic stem cell transplantation SL Caddy, M Wang, P Krishnamurthy, B Uttenthal, A Chandra, C Crawley, ... Innate immunity 24 (2), 112-121, 2018 | 1 | 2018 |
Autoimmune haemolytic anaemia after allogeneic haematopoietic stem cell transplantation: analysis of 555 transplant patients at King’s College Hospital M Wang, W Wang, A Abeywardane 53rd Annual Scientific Meeting of the British Society for Haematology, 2013 | 1 | 2013 |
Targeting leukemia with a metabolic genotoxin M Wang Blood, The Journal of the American Society of Hematology 141 (19), 2293-2295, 2023 | | 2023 |
3216–GENOTOXIC FORMALDEHYDE ACCELERATES AGEING IN HEMATOPOIETIC STEM CELLS IN A P53-DRIVEN MANNER M Wang, L Brandt, X Wang, H Russell, E Mitchell, A Kamimae-Lanning, ... Experimental Hematology 124, S157, 2023 | | 2023 |
P1416: DNA DAMAGE TRIGGERS A P53 INDUCED AGEING RESPONSE IN HAEMATOPOIETIC STEM CELLS M Wang, L Brandt, X Wang, J Garaycoechea, N Wilson, B Göttgens, ... Hemasphere 6 (Suppl), 2022 | | 2022 |