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Justin Long
Justin Long
Assistant Professor, Washington University School of Medicine
在 wustl.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Alzheimer disease: an update on pathobiology and treatment strategies
JM Long, DM Holtzman
Cell 179 (2), 312-339, 2019
21452019
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model
Y Shi, M Manis, J Long, K Wang, PM Sullivan, J Remolina Serrano, ...
Journal of Experimental Medicine 216 (11), 2546-2561, 2019
3062019
MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed
JM Long, DK Lahiri
Biochemical and biophysical research communications 404 (4), 889-895, 2011
2522011
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients
JM Long, B Ray, DK Lahiri
Journal of Biological Chemistry 287 (37), 31298-31310, 2012
2172012
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue …
JM Long, B Ray, DK Lahiri
Journal of Biological Chemistry 289 (8), 5184-5198, 2014
1982014
Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links
DK Sokol, B Maloney, JM Long, B Ray, DK Lahiri
Neurology 76 (15), 1344-1352, 2011
1702011
Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker
B Ray, JM Long, DK Sokol, DK Lahiri
PLoS One 6 (6), e20405, 2011
1332011
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease
JM Long, B Maloney, JT Rogers, DK Lahiri
Molecular psychiatry 24 (3), 345-363, 2019
1312019
Lessons from a BACE1 inhibitor trial: off‐site but not off base
DK Lahiri, B Maloney, JM Long, NH Greig
Alzheimer's & Dementia 10, S411-S419, 2014
1022014
Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research
B Ray, N Chopra, JM Long, DK Lahiri
Molecular brain 7 (1), 63, 2014
512014
Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders
JM Long, DK Lahiri
Experimental neurology 235 (2), 402-418, 2012
452012
Current drug targets for modulating Alzheimer's amyloid precursor protein: role of specific micro-RNA species
JM Long, DK Lahiri
Current medicinal chemistry 18 (22), 3314-3321, 2011
352011
Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia
LN Koenig, GS Day, A Salter, S Keefe, LM Marple, J Long, P LaMontagne, ...
NeuroImage: Clinical, 102248, 2020
302020
Autoimmune dementia
JM Long, GS Day
Seminars in neurology 38 (03), 303-315, 2018
262018
Preclinical Alzheimer’s disease biomarkers accurately predict cognitive and neuropathological outcomes
JM Long, DW Coble, C Xiong, SE Schindler, RJ Perrin, BA Gordon, ...
Brain, 2022
232022
Biochemical evidence for the dysregulation of Alzheimer’s amyloid precursor protein (APP) expression and metabolism in Fragile X syndrome (FXS) and severe autism
DK Lahiri, JM Long, B Ray, DK Sokol
Society of Biological Psychiatry, 2011
52011
P3‐157: A novel microRNA interaction relevant to alzheimer's disease pathogenesis and drug target discovery: miR‐346 induces expression of amyloid precursor protein
J Long, D Lahiri
Alzheimer's & Dementia 7, S566-S567, 2011
32011
Potential Alzheimer's Disease Markers for Autism? Beta-Amyloid Precursor Protein and Acetylcholinesterase Correlate with Aggression in Autism
DK Sokol, J Long, B Maloney, DM Chen, DK Lahiri
NEUROLOGY 72 (11), A53-A53, 2009
32009
P3‐438: The effect of memantine and rivastigmine on synaptic markers and amyloid processing in cell culture and animal models of Alzheimer's disease
DK Lahiri, JA Bailey, B Ray, H Tanila, P Banerjee, J Long
Alzheimer's & Dementia 6, S581-S582, 2010
22010
MicroRNA-346 stimulates APP expression by blockading an iron response element in the APP 5'-UTR: A novel therapeutic target for Alzheimer's disease (AD)
D Lahiri, J Long, N Chopra, B Ray
Alzheimer's & Dementia 4 (9), P839, 2013
1*2013
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