Alzheimer disease: an update on pathobiology and treatment strategies JM Long, DM Holtzman Cell 179 (2), 312-339, 2019 | 2145 | 2019 |
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model Y Shi, M Manis, J Long, K Wang, PM Sullivan, J Remolina Serrano, ... Journal of Experimental Medicine 216 (11), 2546-2561, 2019 | 306 | 2019 |
MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed JM Long, DK Lahiri Biochemical and biophysical research communications 404 (4), 889-895, 2011 | 252 | 2011 |
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients JM Long, B Ray, DK Lahiri Journal of Biological Chemistry 287 (37), 31298-31310, 2012 | 217 | 2012 |
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue … JM Long, B Ray, DK Lahiri Journal of Biological Chemistry 289 (8), 5184-5198, 2014 | 198 | 2014 |
Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links DK Sokol, B Maloney, JM Long, B Ray, DK Lahiri Neurology 76 (15), 1344-1352, 2011 | 170 | 2011 |
Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker B Ray, JM Long, DK Sokol, DK Lahiri PLoS One 6 (6), e20405, 2011 | 133 | 2011 |
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease JM Long, B Maloney, JT Rogers, DK Lahiri Molecular psychiatry 24 (3), 345-363, 2019 | 131 | 2019 |
Lessons from a BACE1 inhibitor trial: off‐site but not off base DK Lahiri, B Maloney, JM Long, NH Greig Alzheimer's & Dementia 10, S411-S419, 2014 | 102 | 2014 |
Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research B Ray, N Chopra, JM Long, DK Lahiri Molecular brain 7 (1), 63, 2014 | 51 | 2014 |
Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders JM Long, DK Lahiri Experimental neurology 235 (2), 402-418, 2012 | 45 | 2012 |
Current drug targets for modulating Alzheimer's amyloid precursor protein: role of specific micro-RNA species JM Long, DK Lahiri Current medicinal chemistry 18 (22), 3314-3321, 2011 | 35 | 2011 |
Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia LN Koenig, GS Day, A Salter, S Keefe, LM Marple, J Long, P LaMontagne, ... NeuroImage: Clinical, 102248, 2020 | 30 | 2020 |
Autoimmune dementia JM Long, GS Day Seminars in neurology 38 (03), 303-315, 2018 | 26 | 2018 |
Preclinical Alzheimer’s disease biomarkers accurately predict cognitive and neuropathological outcomes JM Long, DW Coble, C Xiong, SE Schindler, RJ Perrin, BA Gordon, ... Brain, 2022 | 23 | 2022 |
Biochemical evidence for the dysregulation of Alzheimer’s amyloid precursor protein (APP) expression and metabolism in Fragile X syndrome (FXS) and severe autism DK Lahiri, JM Long, B Ray, DK Sokol Society of Biological Psychiatry, 2011 | 5 | 2011 |
P3‐157: A novel microRNA interaction relevant to alzheimer's disease pathogenesis and drug target discovery: miR‐346 induces expression of amyloid precursor protein J Long, D Lahiri Alzheimer's & Dementia 7, S566-S567, 2011 | 3 | 2011 |
Potential Alzheimer's Disease Markers for Autism? Beta-Amyloid Precursor Protein and Acetylcholinesterase Correlate with Aggression in Autism DK Sokol, J Long, B Maloney, DM Chen, DK Lahiri NEUROLOGY 72 (11), A53-A53, 2009 | 3 | 2009 |
P3‐438: The effect of memantine and rivastigmine on synaptic markers and amyloid processing in cell culture and animal models of Alzheimer's disease DK Lahiri, JA Bailey, B Ray, H Tanila, P Banerjee, J Long Alzheimer's & Dementia 6, S581-S582, 2010 | 2 | 2010 |
MicroRNA-346 stimulates APP expression by blockading an iron response element in the APP 5'-UTR: A novel therapeutic target for Alzheimer's disease (AD) D Lahiri, J Long, N Chopra, B Ray Alzheimer's & Dementia 4 (9), P839, 2013 | 1* | 2013 |