Gene essentiality and synthetic lethality in haploid human cells VA Blomen, P Májek, LT Jae, JW Bigenzahn, J Nieuwenhuis, J Staring, ... Science, aac7557, 2015 | 878 | 2015 |
Critical assessment of automated flow cytometry data analysis techniques N Aghaeepour, G Finak, H Hoos, TR Mosmann, R Brinkman, R Gottardo, ... Nature methods 10 (3), 228, 2013 | 672 | 2013 |
Artemisinins target GABAA receptor signaling and impair α cell identity J Li, T Casteels, T Frogne, C Ingvorsen, C Honore, M Courtney, ... Cell 168 (1-2), 86-100. e15, 2017 | 390 | 2017 |
Early-onset inflammatory bowel disease and common variable immunodeficiency–like disease caused by IL-21 deficiency E Salzer, A Kansu, H Sic, P Májek, A Ikincioğullari, FE Dogu, ... Journal of Allergy and Clinical Immunology 133 (6), 1651-1659. e12, 2014 | 156 | 2014 |
Allosteric transitions of supramolecular systems explored by network models: application to chaperonin GroEL Z Yang, P Májek, I Bahar PLoS computational biology 5 (4), e1000360, 2009 | 152 | 2009 |
Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity KL Willmann, S Klaver, F Doğu, E Santos-Valente, W Garncarz, I Bilic, ... Nature communications 5 (1), 5360, 2014 | 143 | 2014 |
Milestoning without a reaction coordinate P Májek, R Elber Journal of chemical theory and computation 6 (6), 1805-1817, 2010 | 134 | 2010 |
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers. S Schick, AF Rendeiro, K Runggatscher, A Ringler, B Boidol, M Hinkel, ... Nat. Genet 51, 1399-1410, 2019 | 124 | 2019 |
Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function A Lercher, A Bhattacharya, AM Popa, M Caldera, MF Schlapansky, ... Immunity 51 (6), 1074-1087. e9, 2019 | 81 | 2019 |
Lymphatic exosomes promote dendritic cell migration along guidance cues M Brown, LA Johnson, DA Leone, P Majek, K Vaahtomeri, D Senfter, ... Journal of Cell Biology 217 (6), 2205-2221, 2018 | 81 | 2018 |
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation S Sdelci, AF Rendeiro, P Rathert, W You, JMG Lin, A Ringler, G Hofstätter, ... Nature genetics 51 (6), 990-998, 2019 | 74 | 2019 |
A coarse‐grained potential for fold recognition and molecular dynamics simulations of proteins P Májek, R Elber Proteins: Structure, Function, and Bioinformatics 76 (4), 822-836, 2009 | 56 | 2009 |
Complement activation in peritoneal dialysis–induced arteriolopathy M Bartosova, B Schaefer, JL Bermejo, S Tarantino, F Lasitschka, ... Journal of the American Society of Nephrology 29 (1), 268-282, 2018 | 53 | 2018 |
The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease L Kosack, B Wingelhofer, A Popa, A Orlova, B Agerer, B Vilagos, P Majek, ... Cancer Cell 35 (1), 125-139. e9, 2019 | 48 | 2019 |
24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation C Zhu, N Boucheron, AC Müller, P Májek, T Claudel, E Halilbasic, ... Journal of Hepatology 75 (5), 1164-1176, 2021 | 33 | 2021 |
Building and assessing atomic models of proteins from structural templates: Learning and benchmarks BK Vallat, J Pillardy, P Májek, J Meller, T Blom, BQ Cao, R Elber Proteins: Structure, Function, and Bioinformatics 76 (4), 930-945, 2009 | 31 | 2009 |
Mapping the human kinome in response to DNA damage M Owusu, P Bannauer, JF da Silva, TP Mourikis, A Jones, P Májek, ... Cell Reports 26 (3), 555-563. e6, 2019 | 29 | 2019 |
Identifying kinase substrates via a heavy ATP kinase assay and quantitative mass spectrometry AC Müller, R Giambruno, J Weißer, P Májek, A Hofer, JW Bigenzahn, ... Scientific reports 6 (1), 28107, 2016 | 29 | 2016 |
Effects of alanyl-glutamine treatment on the peritoneal dialysis effluent proteome reveal pathomechanism-associated molecular signatures R Herzog, M Boehm, M Unterwurzacher, A Wagner, K Parapatics, ... Molecular & Cellular Proteomics 17 (3), 516-532, 2018 | 26 | 2018 |
Experiments and comprehensive simulations of the formation of a helical turn GS Jas, WA Hegefeld, P Májek, K Kuczera, R Elber The Journal of Physical Chemistry B 116 (23), 6598-6610, 2012 | 25 | 2012 |