| Cysteine proteases in protozoan parasites JL Siqueira-Neto, A Debnath, LI McCall, JA Bernatchez, M Ndao, ... PLoS Neglected Tropical Diseases 12 (8), e0006512, 2018 | 160 | 2018 |
| Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell Stem Cell 26 (2), 187-204, 2020 | 142 | 2020 |
| Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B MH Powdrill, JA Bernatchez, M Götte Viruses 2 (10), 2169-2195, 2010 | 119 | 2010 |
| Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy Y Luan, J Li, JA Bernatchez, R Li Journal of Medicinal Chemistry 62 (7), 3171-3183, 2019 | 113 | 2019 |
| Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ... Journal of Experimental Medicine 216 (5), 1071-1090, 2019 | 102 | 2019 |
| Drugs for the Treatment of Zika Virus Infection JA Bernatchez, LT Tran, J Li, Y Luan, JL Siqueira-Neto, R Li Journal of Medicinal Chemistry 63 (2), 470-489, 2020 | 88 | 2020 |
| Machine Learning Models Identify Inhibitors of SARS-CoV-2 VO Gawriljuk, PPK Zin, AC Puhl, KM Zorn, DH Foil, TR Lane, B Hurst, ... Journal of Chemical Information and Modeling, 2021 | 44 | 2021 |
| Mass spectrometry-based chemical cartography of a cardiac parasitic infection LI McCall, JT Morton, JA Bernatchez, JL de Siqueira-Neto, R Knight, ... Analytical chemistry 89 (19), 10414-10421, 2017 | 43 | 2017 |
| The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies BC Prager, HN Vasudevan, D Dixit, JA Bernatchez, Q Wu, LC Wallace, ... Cancer Discovery 10, 1722–1741, 2020 | 42 | 2020 |
| Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells Z Qiu, L Zhao, JZ Shen, Z Liang, Q Wu, K Yang, L Min, RC Gimple, ... Cancer Discovery, 2021 | 39 | 2021 |
| Mechanism of action of methotrexate against Zika virus S Beck, Z Zhu, MF Oliveira, DM Smith, JN Rich, JA Bernatchez, ... Viruses 11 (4), 338, 2019 | 38 | 2019 |
| Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics J Balzarini, K Das, JA Bernatchez, SE Martinez, M Ngure, S Keane, ... Proceedings of the National Academy of Sciences 112 (11), 3475-3480, 2015 | 38 | 2015 |
| Dynamics of hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B in complex with RNA P Karam, MH Powdrill, HW Liu, C Vasquez, W Mah, J Bernatchez, M Götte, ... Journal of Biological Chemistry 289 (20), 14399-14411, 2014 | 35 | 2014 |
| Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases L Li, BC Chenna, KS Yang, TR Cole, ZT Goodall, M Giardini, ... Journal of Medicinal Chemistry, 2021 | 28 | 2021 |
| Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting Zika virus JA Bernatchez, Z Yang, M Coste, J Li, S Beck, Y Liu, AE Clark, Z Zhu, ... Antimicrobial agents and chemotherapy 62 (10), 10.1128/aac. 00725-18, 2018 | 27 | 2018 |
| Peptidomimetic Vinyl Heterocycle Inhibitors of Cruzain Effect Anti-Trypanosomal Activity BC Chenna, L Li, DM Mellott, X Zhai, JL Siqueira-Neto, CM Calvet Alvarez, ... Journal of Medicinal Chemistry 63 (6), 3298–3316, 2020 | 24 | 2020 |
| Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors B Singh, JA Bernatchez, LI McCall, CM Calvet, J Ackermann, JM Souza, ... ACS Medicinal Chemistry Letters 11 (3), 249–257, 2020 | 20 | 2020 |
| Insights gained into respiratory infection pathogenesis using lung tissue metabolomics JA Bernatchez, LI McCall PLoS Pathogens 16 (7), e1008662, 2020 | 18 | 2020 |
| Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer M Ehteshami, M Nijhuis, JA Bernatchez, CJ Ablenas, S McCormick, ... Journal of Biological Chemistry 288 (24), 17336-17346, 2013 | 17 | 2013 |
| Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase JA Bernatchez, R Paul, EP Tchesnokov, M Ngure, GL Beilhartz, ... Journal of Biological Chemistry 290 (3), 1474-1484, 2015 | 16 | 2015 |
