| Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy AS Dekhne, K Shah, GS Ducker, JM Katinas, J Wong-Roushar, ... Molecular cancer therapeutics 18 (10), 1787-1799, 2019 | 50 | 2019 |
| Cellular pharmacodynamics of a novel pyrrolo [3, 2-d] pyrimidine inhibitor targeting mitochondrial and cytosolic one-carbon metabolism AS Dekhne, C Ning, MJ Nayeen, K Shah, H Kalpage, J Frühauf, ... Molecular Pharmacology 97 (1), 9-22, 2020 | 33 | 2020 |
| Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo [2, 3-d] pyrimidines as dihydrofolate reductase inhibitors … K Shah, X Lin, SF Queener, V Cody, J Pace, A Gangjee Bioorganic & medicinal chemistry 26 (9), 2640-2650, 2018 | 11 | 2018 |
| Development of substituted pyrido [3, 2-d] pyrimidines as potent and selective dihydrofolate reductase inhibitors for pneumocystis pneumonia infection K Shah, S Queener, V Cody, J Pace, A Gangjee Bioorganic & medicinal chemistry letters 29 (15), 1874-1880, 2019 | 7 | 2019 |
| Sterically induced conformational restriction: Discovery and preclinical evaluation of novel pyrrolo [3, 2-d] pyrimidines as microtubule targeting agents RK Pavana, K Shah, T Gentile, NF Dybdal-Hargreaves, AL Risinger, ... Bioorganic & medicinal chemistry 26 (20), 5470-5478, 2018 | 7 | 2018 |
| Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria MJ Nayeen, JM Katinas, T Magdum, K Shah, JE Wong, CE O’Connor, ... Journal of Medicinal Chemistry 66 (16), 11294-11323, 2023 | 5 | 2023 |
| Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2 JM Katinas, MJ Nayeen, M Schneider, K Shah, AN Fifer, LM Klapper, ... Biochemistry 63 (4), 545-562, 2024 | 3 | 2024 |
| Design and biological evaluation of substituted pyrrolo [3, 2-d] pyrimidines as dual acting RTK and microtubule targeting agents A Gangjee, K Shah, N Dybdal-Hargreaves, S Mooberry, A Bastian, ... Cancer Research 76 (14_Supplement), 4857-4857, 2016 | 3 | 2016 |
| Emotional Intelligence: A basic Concept PP Patel, KS Shah Journal of Educational and Psychology 59 (2-3), 2001 | 3 | 2001 |
| Biodegradation of Azo Dye (Congo Red) by Bacterial Isolate from the Textile Effluent Contaminated Soil K Shah, P Andhare, I Bhattacharya, A Thakur, D Upadhyay | 1 | 2022 |
| Targeting mitochondrial and cytosolic one-carbon metabolism in epithelial ovarian cancer via folate receptor alpha AC Wallace-Povirk, C O'Connor, X Bao, J Katinas, J Wong-Roushar, ... Cancer Research 81 (13_Supplement), 2348-2348, 2021 | 1 | 2021 |
| 10 years of biosimilars: lessons and trends I Royzman, K Shah Nat Rev Drug Discov., 2019 | 1 | 2019 |
| first-in-class, fluorinated folate receptor specific agents that target tumor cells via inhibition of serine hydroxymethyltransferase 2 (SHMT2) and 5-aminoimidazole-4 … MJ Nayeen, K Shah, A Gangjee, A Dekhne, Z Hou, LH Matherly Cancer Research 78 (13_Supplement), 1656-1656, 2018 | 1 | 2018 |
| Target based design and synthesis of fused pyrimidines in the potential treatment of cancer and opportunistic infection K Shah Duquesne University, 2017 | 1 | 2017 |
| Design, synthesis, and biological evaluation of thieno [3, 2-d] pyrimidines as potent antimitotic and antitumor agents A Gangjee, T Quadery, K Shah, W Xiang, X Zhou, A Perez, S Mooberry ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | 1 | 2015 |
| Role of mitochondrial and cytosolic folylpolyglutamate synthetase in one-carbon metabolism and antitumor efficacy of mitochondrial-targeted antifolates C O’Connor, M Schneider, JM Katinas, MJ Nayeen, K Shah, T Magdum, ... Molecular Pharmacology 106 (4), 173-187, 2024 | | 2024 |
| Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy AS Dekhne, K Shah, GS Ducker, JM Katinas, J Wong-Roushar, ... Molecular Cancer Therapeutics 22 (2), 287-287, 2023 | | 2023 |
| Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2-d]pyrimidine antifolates A Dekhne, K Shah, GS Ducker, MJ Nayeen, JM Katinas, J Wong, A Doshi, ... Cancer Research 79 (13_Supplement), 2992-2992, 2019 | | 2019 |
| Multi-targeted inhibitors of mitochondrial one-carbon metabolism and cytosolic de novo purine synthesis enzymes as anti-tumor agents MJ Nayeen, K Shah, A Dekhne, C Ning, C O'Connor, JM Katinas, J Wong, ... Cancer Research 79 (13_Supplement), 811-811, 2019 | | 2019 |
| Multi-targeted novel 5-substituted pyrrolo[3,2-d]pyrimidines with tumor-selective targeting and inhibition of cytosolic de novo purine biosynthesis and mitochondrial … N Tong, K Shah, A Gangjee, C O’Connor, AW Porvirk, A Dekhne, Z Hou, ... Cancer Research 79 (13_Supplement), 789-789, 2019 | | 2019 |
Larry MatherlyKarmanos Cancer Institute/Wayne State University在 karmanos.org 的电子邮件经过验证
