| Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit H Medyouf, M Mossner, JC Jann, F Nolte, S Raffel, C Herrmann, A Lier, ... Cell stem cell 14 (6), 824-837, 2014 | 439 | 2014 |
| Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure M Mossner, JC Jann, J Wittig, F Nolte, S Fey, V Nowak, J Obländer, ... Blood, The Journal of the American Society of Hematology 128 (9), 1246-1259, 2016 | 141 | 2016 |
| Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states S Triana, D Vonficht, L Jopp-Saile, S Raffel, R Lutz, D Leonce, M Antes, ... Nature immunology 22 (12), 1577-1589, 2021 | 121 | 2021 |
| Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics L Velten, BA Story, P Hernández-Malmierca, S Raffel, DR Leonce, ... Nature communications 12 (1), 1366, 2021 | 103 | 2021 |
| Effects of the environmental contaminants DEHP and TCDD on estradiol synthesis and aryl hydrocarbon receptor and peroxisome proliferator-activated receptor signalling in the … J Ernst, JC Jann, R Biemann, HM Koch, B Fischer Molecular human reproduction 20 (9), 919-928, 2014 | 81 | 2014 |
| Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from … M Mossner, JC Jann, D Nowak, U Platzbecker, A Giagounidis, K Goetze, ... Leukemia 30 (9), 1956-1959, 2016 | 74 | 2016 |
| Cohesin mutations in myeloid malignancies JC Jann, Z Tothova Blood, The Journal of the American Society of Hematology 138 (8), 649-661, 2021 | 33 | 2021 |
| Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations J Flach, JC Jann, A Knaflic, V Riabov, A Streuer, E Altrock, Q Xu, ... Haematologica 106 (11), 2906, 2021 | 30 | 2021 |
| Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance D Nowak, NLM Liem, M Mossner, M Klaumünzer, RA Papa, V Nowak, ... Experimental hematology 43 (1), 32-43. e35, 2015 | 29 | 2015 |
| Functional analysis of structural variants in single cells using Strand-seq H Jeong, K Grimes, KK Rauwolf, PM Bruch, T Rausch, P Hasenfeld, ... Nature biotechnology 41 (6), 832-844, 2023 | 20 | 2023 |
| Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo JC Jann, M Mossner, V Riabov, E Altrock, N Schmitt, J Flach, Q Xu, ... Nature communications 12 (1), 6170, 2021 | 20 | 2021 |
| Characterization of stem-like circulating tumor cells in pancreatic cancer L Zhu, B Hissa, B Győrffy, JC Jann, C Yang, C Reissfelder, S Schölch Diagnostics 10 (5), 305, 2020 | 12 | 2020 |
| Safety and efficacy of the CD95-ligand inhibitor asunercept in transfusion-dependent patients with low and intermediate risk MDS T Boch, T Luft, G Metzgeroth, M Mossner, JC Jann, D Nowak, F La Meir, ... Leukemia Research 68, 62-69, 2018 | 12 | 2018 |
| Deep sequencing of bone marrow microenvironments of patients with del (5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T … T Mährle, N Akyüz, P Fuchs, N Bonzanni, D Simnica, U Germing, ... Haematologica 104 (7), 1355, 2019 | 10 | 2019 |
| Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes N Schmitt, JC Jann, E Altrock, J Flach, J Danner, S Uhlig, A Streuer, ... Leukemia 36 (1), 236-247, 2022 | 9 | 2022 |
| High erythroferrone expression in CD71+ erythroid progenitors predicts superior survival in myelodysplastic syndromes V Riabov, M Mossner, A Stöhr, JC Jann, A Streuer, N Schmitt, A Knaflic, ... British journal of haematology 192 (5), 879-891, 2021 | 9 | 2021 |
| Humanized three-dimensional scaffold xenotransplantation models for myelodysplastic syndromes E Altrock, C Sens-Albert, JC Jann, J Flach, V Riabov, N Schmitt, Q Xu, ... Experimental Hematology 107, 38-50, 2022 | 7 | 2022 |
| Concomitant MDS with isolated 5q deletion and MGUS: case report and review of molecular aspects F Nolte, M Mossner, JC Jann, D Nowak, T Boch, NZ Müller, WK Hofmann, ... European Journal of Haematology 98 (3), 302-310, 2017 | 7 | 2017 |
| Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML EC Wheeler, BJE Martin, WC Doyle, S Neaher, CA Conway, CN Pitton, ... Science translational medicine 16 (728), eade2774, 2024 | 6 | 2024 |
| RNA-sequencing of acute promyelocytic leukemia primary blasts reveals novel molecular biomarkers of early death events JC Jann, A Streuer, A Hecht, F Nolte, V Nowak, J Danner, J Obländer, ... Leukemia & Lymphoma 61 (13), 3066-3077, 2020 | 6 | 2020 |
