| Rufomycin targets ClpC1 proteolysis in Mycobacterium tuberculosis and M. abscessus MP Choules, NM Wolf, H Lee, JR Anderson, EM Grzelak, Y Wang, R Ma, ... Antimicrobial agents and chemotherapy 63 (3), 10.1128/aac. 02204-18, 2019 | 96 | 2019 |
| High-resolution structure of ClpC1-rufomycin and ligand binding studies provide a framework to design and optimize anti-tuberculosis leads NM Wolf, H Lee, MP Choules, GF Pauli, R Phansalkar, JR Anderson, ... ACS infectious diseases 5 (6), 829-840, 2019 | 53 | 2019 |
| Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502 B Zhou, G Shetye, Y Yu, BD Santarsiero, LL Klein, C Abad-Zapatero, ... Journal of natural products 83 (3), 657-667, 2020 | 37 | 2020 |
| Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions NM Wolf, H Lee, D Zagal, JW Nam, DC Oh, JW Suh, GF Pauli, S Cho, ... Acta Crystallographica Section D: Structural Biology 76 (5), 458-471, 2020 | 32 | 2020 |
| Identification of Bacillus anthracis PurE inhibitors with antimicrobial activity A Kim, NM Wolf, T Zhu, ME Johnson, J Deng, JL Cook, LWM Fung Bioorganic & medicinal chemistry 23 (7), 1492-1499, 2015 | 28 | 2015 |
| Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg2+, AIR and Asp NM Wolf, C Abad-Zapatero, ME Johnson, LWM Fung Acta Crystallographica Section D: Biological Crystallography 70 (3), 841-850, 2014 | 16 | 2014 |
| Identification of B. anthracis N5-carboxyaminoimidazole ribonucleotide mutase (PurE) active site binding compounds via fragment library screening H Lei, C Jones, T Zhu, K Patel, NM Wolf, LWM Fung, H Lee, ME Johnson Bioorganic & Medicinal Chemistry 24 (4), 596-605, 2016 | 12 | 2016 |
| Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1, 6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate … NM Wolf, HJ Gutka, F Movahedzadeh, C Abad-Zapatero Acta Crystallographica Section D: Structural Biology 74 (4), 321-331, 2018 | 8 | 2018 |
| Enzymatic Characterization of Fructose 1,6-Bisphosphatase II from Francisella tularensis, an Essential Enzyme for Pathogenesis HJ Gutka, NM Wolf, JMG Bondoc, F Movahedzadeh Applied biochemistry and biotechnology 183, 1439-1454, 2017 | 8 | 2017 |
| Mutagenesis of threonine to serine in the active site of Mycobacterium tuberculosis fructose-1, 6-bisphosphatase (Class II) retains partial enzyme activity JMG Bondoc, NM Wolf, M Ndichuck, C Abad-Zapatero, F Movahedzadeh Biotechnology reports 15, 48-54, 2017 | 6 | 2017 |
| Structural and biochemical characterization of the class II fructose-1, 6-bisphosphatase from Francisella tularensis AI Selezneva, HJ Gutka, NM Wolf, F Qurratulain, F Movahedzadeh, ... Acta Crystallographica Section F: Structural Biology Communications 76 (11 …, 2020 | 4 | 2020 |
| New Rufomycins from Streptomyces atratus MJM3502 Expand Anti-Mycobacterium tuberculosis Structure–Activity Relationships B Zhou, G Shetye, NM Wolf, SN Chen, M Qader, GJ Ray, DC Lankin, ... Organic letters 24 (40), 7265-7270, 2022 | 3 | 2022 |
| Differences in the purification and solution properties of PurC gene products from Streptococcus pneumoniae and Bacillus anthracis ML Tuntland, NM Wolf, LWM Fung Protein Expression and Purification 114, 143-148, 2015 | 3 | 2015 |
| Structures of CIpC1-NTD with potent anti-TB cyclic peptides Rufomycin and Ecumicin: Implications for the mechanism of action and design of therapeutic agents NM Wolf, H Lee, J Nam, J Hong, NM Duc, NA Ho, H Lee, J Suh, GF Pauli, ... Acta Cryst. A 75, A59, 2019 | 2 | 2019 |
| Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization JMG Bondoc, HJ Gutka, MM Almutairi, R Patwell, MW Rutter, NM Wolf, ... Acta Crystallographica Section F: Structural Biology Communications 75 (10 …, 2019 | 1 | 2019 |
| High-resolution structure of Clpc1-Ntd-Rufomycin complex provides three-dimensional framework for optimization of cyclopeptide anti-Tb drug leads N Wolf, H Lee, M Choules, L Klein, V Petukhova, M Tufano, R Phansalkar, ... PROTEIN SCIENCE 27, 119-120, 2018 | 1 | 2018 |
| Rufomycin targets ClpC1 proteolysis in Mycobacterium tuberculosis and M. abscessus. SH Cho, MP Choules, NM Wolf, H Lee, JR Anderson, EM Grzelak, ... University of Illinois at Chicago, 2019 | | 2019 |
| Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg2+, AIR and Asp. Corrigendum NM Wolf, C Abad-Zapatero, ME Johnson, LWM Fung Acta Crystallographica Section D: Biological Crystallography 70 (11), 3087-3087, 2014 | | 2014 |
| Biophysical Studies of Enzymes in the Purine Biosynthetic Pathway of Pathogens for Antibiotic Development NM Wolf University of Illinois at Chicago, 2014 | | 2014 |
| Fragment-based lead discovery using a multi-domain, parallel MM/PBSA simulation screening protocol T Zhu, C Jones, H Lei, N Wolf, S Mehboob, L Huma, H Lee, K Patel, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |
