Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature biotechnology 35 (1), 31-34, 2017 | 954 | 2017 |
DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute JW Hegge, DC Swarts, SD Chandradoss, TJ Cui, J Kneppers, M Jinek, ... Nucleic acids research 47 (11), 5809-5821, 2019 | 121 | 2019 |
Oligometastatic prostate cancer: results of a Dutch multidisciplinary consensus meeting SS Aluwini, N Mehra, MP Lolkema, DE Oprea-Lager, D Yakar, ... European urology oncology 3 (2), 231-238, 2020 | 47 | 2020 |
Frequent clonal relations between metastases and non-index prostate cancer lesions J Kneppers, O Krijgsman, M Melis, J de Jong, DS Peeper, E Bekers, ... JCI insight 4 (2), 2019 | 32 | 2019 |
Erratum: Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature Biotechnology 35 (2), 178-178, 2017 | 22 | 2017 |
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential J Kneppers, TM Severson, JC Siefert, P Schol, SEP Joosten, IPL Yu, ... Nature Communications 13 (1), 7367, 2022 | 11 | 2022 |
Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients TM Severson, Y Zhu, S Prekovic, K Schuurman, HM Nguyen, LG Brown, ... medRxiv, 2023.02. 24.23286403, 2023 | 3 | 2023 |
Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties MNG van Genderen, J Kneppers, A Zaalberg, EM Bekers, AM Bergman, ... npj Systems Biology and Applications 10 (1), 20, 2024 | 1 | 2024 |
Exploring the onset and progression of prostate cancer through a multicellular agent-based model M Passier, MNG van Genderen, A Zaalberg, J Kneppers, EM Bekers, ... Cancer Research Communications 3 (8), 1473-1485, 2023 | 1 | 2023 |
Somatostatin receptor 1 (SSTR1) expression as a potential predictive biomarker for response to androgen receptor signaling inhibitor (ARSI) therapy in metastatic … X Zhu, DJ Vis, M Sjöström, R Shrestha, J Kneppers, T Severson, Y Zhu, ... Journal of Clinical Oncology 42 (4_suppl), 180-180, 2024 | | 2024 |
Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties F Eduati, M van Genderen, J Kneppers, A Zaalberg, E Bekers, A Bergman, ... | | 2023 |
Abstract A029: Whole genome and transcriptome analysis of paired metastatic biopsies identified resistance mechanisms in castration-resistant prostate cancer X Zhu, D Vis, M Sjöström, R Shrestha, J Kneppers, T Severson, Y Zhu, ... Cancer Research 83 (11_Supplement), A029-A029, 2023 | | 2023 |
Understanding the divergence of prostate cancer genomics among patients: The multifaceted face of prostate cancer JJP Kneppers | | 2023 |
Prostate Cancer Epigenetic Plasticity and Enhancer Heterogeneity: Molecular Causes, Consequences and Clinical Implications J Kneppers, AM Bergman, W Zwart Nuclear Receptors in Human Health and Disease, 255-275, 2022 | | 2022 |
Prognostic value of the clonal origin of lymph node metastases in prostate cancer HA De Barros, J Kneppers, PJ Van Leeuwen, W Zwart, AM Bergman, ... European Urology Open Science 33, S271-S272, 2021 | | 2021 |
Re: Andrew Erickson, Alicia Hayes, Timothy Rajakumar, et al. A Systematic Review of Prostate Cancer Heterogeneity: Understanding the Clonal Ancestry of Multifocal Disease. Eur … J Kneppers, H de Barros, H van der Poel European Urology Oncology 4 (5), 851, 2021 | | 2021 |
Multiplex gene editing by CRISPR-Cpf1 through autonomous processing of a single crRNA array J Kneppers, EM DeGennaro, N Winblad, SR Choudhury, OO Abudayyeh, ... | | |