| Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space EK Makowski, PC Kinnunen, J Huang, L Wu, MD Smith, T Wang, ... Nature communications 13 (1), 3788, 2022 | 75 | 2022 |
| Protein adsorption to charged gold nanospheres as a function of protein deformability JM Dennison, JM Zupancic, W Lin, JH Dwyer, CJ Murphy Langmuir 33 (31), 7751-7761, 2017 | 58 | 2017 |
| Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis JM Zupancic, AA Desai, JS Schardt, G Pornnoppadol, EK Makowski, ... Cell chemical biology 28 (9), 1379-1388. e7, 2021 | 32 | 2021 |
| Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants JM Zupancic, JS Schardt, AA Desai, EK Makowski, MD Smith, ... Advanced Therapeutics 4 (8), 2100099, 2021 | 32 | 2021 |
| Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity AA Desai, MD Smith, Y Zhang, EK Makowski, JE Gerson, E Ionescu, ... Journal of Biological Chemistry 296, 2021 | 23 | 2021 |
| Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening JS Schardt, G Pornnoppadol, AA Desai, KS Park, JM Zupancic, ... Scientific Reports 11 (1), 20738, 2021 | 12 | 2021 |
| Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning EK Makowski, T Wang, JM Zupancic, J Huang, L Wu, JS Schardt, ... Nature Biomedical Engineering 8 (1), 45-56, 2024 | 11 | 2024 |
| Reduction of therapeutic antibody self-association using yeast-display selections and machine learning EK Makowski, H Chen, M Lambert, EM Bennett, NS Eschmann, Y Zhang, ... Mabs 14 (1), 2146629, 2022 | 11 | 2022 |
| Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs G Pornnoppadol, LG Bond, MJ Lucas, JM Zupancic, YH Kuo, B Zhang, ... Cell Chemical Biology 31 (2), 361-372. e8, 2024 | 8 | 2024 |
| Facile isolation of high-affinity nanobodies from synthetic libraries using CDR-swapping mutagenesis JM Zupancic, AA Desai, PM Tessier STAR protocols 3 (1), 101101, 2022 | 4 | 2022 |
| Rapid and Quantitative In Vitro Evaluation of SARS-CoV-2 Neutralizing Antibodies and Nanobodies W Wu, X Tan, J Zupancic, JS Schardt, AA Desai, MD Smith, J Zhang, L Xie, ... Analytical Chemistry 94 (10), 4504-4512, 2022 | 4 | 2022 |
| Isolating Anti-amyloid Antibodies from Yeast-Displayed Libraries AA Desai, JM Zupancic, MD Smith, PM Tessier Yeast Surface Display, 471-490, 2022 | 4 | 2022 |
| Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates JM Zupancic, MD Smith, H Trzeciakiewicz, ME Skinner, SP Ferris, ... Frontiers in Immunology 14, 1164080, 2023 | 2 | 2023 |
| Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils AA Desai, JM Zupancic, H Trzeciakiewicz, JE Gerson, KN DuBois, ... bioRxiv, 2023.07. 04.547698, 2023 | 2 | 2023 |
| Native ion mobility‐mass spectrometry reveals the binding mechanisms of anti‐amyloid therapeutic antibodies Y Han, AA Desai, JM Zupancic, MD Smith, PM Tessier, BT Ruotolo Protein Science 33 (6), e5008, 2024 | | 2024 |
| Development of a pan‐tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates N McArthur, B Kang, FG Rivera Moctezuma, AT Shaikh, K Loeffler, ... Biotechnology Progress, e3463, 2024 | | 2024 |
| Novel Experimental and Computational Approaches for Conformational Antibody Engineering M Smith, A Desai, J Zupancic, P Tessier 2022 AIChE Annual Meeting, 2022 | | 2022 |
| Protein adsorption to charged nanospheres J Dennison, W Lin, J Zupancic, C Murphy ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
