Intra- and Inter-Tumor Heterogeneity of BRAFV600EMutations in Primary and Metastatic Melanoma M Yancovitz, A Litterman, J Yoon, E Ng, RL Shapiro, RS Berman, ... PloS one 7 (1), e29336, 2012 | 335 | 2012 |
Non-viral precision T cell receptor replacement for personalized cell therapy SP Foy, K Jacoby, DA Bota, T Hunter, Z Pan, E Stawiski, Y Ma, W Lu, ... Nature 615 (7953), 687-696, 2023 | 127 | 2023 |
Profound impairment of adaptive immune responses by alkylating chemotherapy AJ Litterman, DM Zellmer, KL Grinnen, MA Hunt, AZ Dudek, AM Salazar, ... The Journal of Immunology 190 (12), 6259-6268, 2013 | 81 | 2013 |
Vaccine injection site matters: qualitative and quantitative defects in CD8 T cells primed as a function of proximity to the tumor in a murine glioma model JR Ohlfest, BM Andersen, AJ Litterman, J Xia, CA Pennell, LE Swier, ... The Journal of Immunology 190 (2), 613-620, 2013 | 72 | 2013 |
miR-15/16 restrain memory T cell differentiation, cell cycle, and survival JD Gagnon, R Kageyama, HM Shehata, MS Fassett, DJ Mar, EJ Wigton, ... Cell reports 28 (8), 2169-2181. e4, 2019 | 71 | 2019 |
Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses WM Dietz, NEB Skinner, SE Hamilton, MD Jund, SM Heitfeld, AJ Litterman, ... Molecular therapy 21 (8), 1526-1535, 2013 | 68 | 2013 |
A massively parallel 3′ UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization AJ Litterman, R Kageyama, O Le Tonqueze, W Zhao, JD Gagnon, ... Genome research 29 (6), 896-906, 2019 | 45 | 2019 |
RNA binding protein CELF2 regulates signal-induced alternative polyadenylation by competing with enhancers of the polyadenylation machinery R Chatrikhi, MJ Mallory, MR Gazzara, LM Agosto, WS Zhu, AJ Litterman, ... Cell reports 28 (11), 2795-2806. e3, 2019 | 37 | 2019 |
Oxygen is a master regulator of the immunogenicity of primary human glioma cells MR Olin, BM Andersen, AJ Litterman, PT Grogan, AL Sarver, ... Cancer research 71 (21), 6583-6589, 2011 | 29 | 2011 |
Effective treatment of established GL261 murine gliomas through picornavirus vaccination-enhanced tumor antigen-specific CD8+ T cell responses DN Renner, F Jin, AJ Litterman, AJ Balgeman, LM Hanson, JD Gamez, ... PLoS One 10 (5), e0125565, 2015 | 28 | 2015 |
Alkylating chemotherapy may exert a uniquely deleterious effect upon neo-antigen-targeting anticancer vaccination AJ Litterman, AZ Dudek, DA Largaespada Oncoimmunology 2 (10), e26294, 2013 | 27 | 2013 |
MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination EJ Wigton, Y Mikami, RJ McMonigle, CA Castellanos, AK Wade-Vallance, ... Journal of Experimental Medicine 218 (11), e20201422, 2021 | 9 | 2021 |
Antigen-specific culture of memory-like CD8 T cells for adoptive immunotherapy AJ Litterman, DM Zellmer, RS LaRue, SC Jameson, DA Largaespada Cancer immunology research 2 (9), 839-845, 2014 | 7 | 2014 |
NeoTCR-P1, a novel neoepitope-specific adoptive cell therapy, consists of T cells with ‘younger’phenotypes that rapidly proliferate and kill target cells upon recognition of … B Sennino, A Conroy, B Purandare, A Litterman, K Jacoby, R Moot, W Lu, ... Cancer Research 79 (13_Supplement), 1433-1433, 2019 | 3 | 2019 |
Optimized CRISPR guide RNA library cloning reduces skew and enables more compact genetic screens SJ Heo, LD Enriquez, S Federman, AY Chang, R Mace, K Shevade, ... BioRxiv, 2022.12. 22.521524, 2022 | 2 | 2022 |
Highly efficient, non-viral precision genome engineering for the generation of personalized neoepitope-specific adoptive T cell therapies K Jacoby, R Moot, W Lu, D Nguyen, B Sennino, A Conroy, B Purandare, ... Cancer Research 79 (13_Supplement), 4783-4783, 2019 | 2 | 2019 |
A global map of RNA binding protein occupancy guides functional dissection of post-transcriptional regulation of the T cell transcriptome AJ Litterman, WS Zhu, R Kageyama, W Zhao, N Zaitlen, DJ Erle, ... bioRxiv, 448654, 2018 | 2 | 2018 |
Detection of BRAF kinase mutations in melanoma, ovarian, and prostate carcinomas: Evidence for tumor heterogeneity in clinical samples AJ Litterman, M Yancovitz, R Shapiro, R Berman, A Pavlick, F Daarvishian, ... Journal of Clinical Oncology 27 (15_suppl), 11031-11031, 2009 | 2 | 2009 |
Tumor heterogeneity: Evidence from BRAF V600E mutation detection AJ Litterman, D Pollens, MA Warycha, RL Shapiro, RS Berman, ... Journal of Clinical Oncology 26 (15_suppl), 20022-20022, 2008 | 2 | 2008 |
Compact CRISPR genetic screens enabled by improved guide RNA library cloning SJ Heo, LD Enriquez, S Federman, AY Chang, R Mace, K Shevade, ... Genome Biology 25 (1), 25, 2024 | 1 | 2024 |