| Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray RK Thimmulappa, KH Mai, S Srisuma, TW Kensler, M Yamamoto, ... Cancer research 62 (18), 5196-5203, 2002 | 1513 | 2002 |
| Dysfunctional KEAP1–NRF2 interaction in non-small-cell lung cancer A Singh, V Misra, RK Thimmulappa, H Lee, S Ames, MO Hoque, ... PLoS medicine 3 (10), e420, 2006 | 1210 | 2006 |
| Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice T Rangasamy, CY Cho, RK Thimmulappa, L Zhen, SS Srisuma, ... The Journal of clinical investigation 114 (9), 1248-1259, 2004 | 1156 | 2004 |
| Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis RK Thimmulappa, H Lee, T Rangasamy, SP Reddy, M Yamamoto, ... The Journal of clinical investigation 116 (4), 984-995, 2016 | 1146 | 2016 |
| Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress CJ Harvey, RK Thimmulappa, A Singh, DJ Blake, G Ling, N Wakabayashi, ... Free Radical Biology and Medicine 46 (4), 443-453, 2009 | 526 | 2009 |
| Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model TE Sussan, S Gajghate, RK Thimmulappa, J Ma, JH Kim, K Sudini, ... PloS one 10 (2), e0116861, 2015 | 471 | 2015 |
| RNAi-mediated silencing of nuclear factor erythroid-2–related factor 2 gene expression in non–small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy A Singh, S Boldin-Adamsky, RK Thimmulappa, SK Rath, H Ashush, ... Cancer research 68 (19), 7975-7984, 2008 | 433 | 2008 |
| Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide RK Thimmulappa, C Scollick, K Traore, M Yates, MA Trush, KT Liby, ... Biochemical and biophysical research communications 351 (4), 883-889, 2006 | 410 | 2006 |
| Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model CJ Harvey, RK Thimmulappa, S Sethi, X Kong, L Yarmus, RH Brown, ... Science translational medicine 3 (78), 78ra32-78ra32, 2011 | 357 | 2011 |
| Glutathione peroxidase 2, the major cigarette smoke–inducible isoform of GPX in lungs, is regulated by Nrf2 A Singh, T Rangasamy, RK Thimmulappa, H Lee, WO Osburn, ... American journal of respiratory cell and molecular biology 35 (6), 639-650, 2006 | 286 | 2006 |
| Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke–induced pulmonary injury and emphysema T Yoshida, I Mett, AK Bhunia, J Bowman, M Perez, L Zhang, A Gandjeva, ... Nature medicine 16 (7), 767-773, 2010 | 254 | 2010 |
| Nickel‐induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects K Doreswamy, B Shrilatha, T Rajeshkumar, Muralidhara Journal of andrology 25 (6), 996-1003, 2004 | 242 | 2004 |
| Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress N Mercado, R Thimmulappa, CMR Thomas, PS Fenwick, KK Chana, ... Biochemical and biophysical research communications 406 (2), 292-298, 2011 | 236 | 2011 |
| Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis X Kong, R Thimmulappa, F Craciun, C Harvey, A Singh, P Kombairaju, ... American journal of respiratory and critical care medicine 184 (8), 928-938, 2011 | 230 | 2011 |
| Role of Nrf2 in protection against intracerebral hemorrhage injury in mice J Wang, J Fields, C Zhao, J Langer, RK Thimmulappa, TW Kensler, ... Free Radical Biology and Medicine 43 (3), 408-414, 2007 | 227 | 2007 |
| Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury ZA Shah, RC Li, RK Thimmulappa, TW Kensler, M Yamamoto, S Biswal, ... Neuroscience 147 (1), 53-59, 2007 | 227 | 2007 |
| Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and age-related macular degeneration M Cano, R Thimmalappula, M Fujihara, N Nagai, M Sporn, AL Wang, ... Vision research 50 (7), 652-664, 2010 | 223 | 2010 |
| Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice TE Sussan, J Jun, R Thimmulappa, D Bedja, M Antero, KL Gabrielson, ... PloS one 3 (11), e3791, 2008 | 207 | 2008 |
| Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility RT Kumar, D K, S B, Muralidhara Mutation Research/Genetic Toxicology and Environmental Mutagenesis 513 (1-2 …, 2002 | 204 | 2002 |
| NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice X Kong, R Thimmulappa, P Kombairaju, S Biswal The Journal of Immunology 185 (1), 569-577, 2010 | 202 | 2010 |
