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Ashley M Thelen
Ashley M Thelen
在 fredhutch.org 的电子邮件经过验证
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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ...
Science 355 (6331), 1306-1311, 2017
4792017
Emerging roles for the lysosome in lipid metabolism
AM Thelen, R Zoncu
Trends in cell biology 27 (11), 833-850, 2017
2042017
Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex
RE Lawrence, SA Fromm, Y Fu, AL Yokom, DJ Kim, AM Thelen, ...
Science 366 (6468), 971-977, 2019
1262019
Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex
LW Brier, L Ge, G Stjepanovic, AM Thelen, JH Hurley, R Schekman
Molecular biology of the cell 30 (9), 1098-1107, 2019
702019
UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the dimer-dimer subunit interfaces
AS Hyde, AM Thelen, JJ Barycki, MA Simpson
Journal of Biological Chemistry 288 (49), 35049-35057, 2013
192013
Inhibiting hexamer disassembly of human UDP-glucose dehydrogenase by photoactivated amino acid cross-linking
G Grady, A Thelen, J Albers, T Ju, J Guo, JJ Barycki, MA Simpson
Biochemistry 55 (22), 3157-3164, 2016
102016
Regulation of mTORC1-Dependent Growth Signaling by Lysosomal Cholesterol
AM Thelen
University of California, Berkeley, 2019
12019
Inhibiting Hexamer Disassembly of Human UDP-Glucose Dehydrogenase by Photoactivated Amino Acid Cross-Linking. Biochemistry 55 (22): 3157-3164.
G Grady, A Thelen, J Albers, T Ju, J Guo, JJ Barycki, MA Simpson
EXAMINATION OF HUMAN UDP-GLUCOSE DEHYDROGENASE STRUCTURE AND FUNCTION …, 2018
2018
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