Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ... Science 355 (6331), 1306-1311, 2017 | 479 | 2017 |
Emerging roles for the lysosome in lipid metabolism AM Thelen, R Zoncu Trends in cell biology 27 (11), 833-850, 2017 | 204 | 2017 |
Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex RE Lawrence, SA Fromm, Y Fu, AL Yokom, DJ Kim, AM Thelen, ... Science 366 (6468), 971-977, 2019 | 126 | 2019 |
Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex LW Brier, L Ge, G Stjepanovic, AM Thelen, JH Hurley, R Schekman Molecular biology of the cell 30 (9), 1098-1107, 2019 | 70 | 2019 |
UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the dimer-dimer subunit interfaces AS Hyde, AM Thelen, JJ Barycki, MA Simpson Journal of Biological Chemistry 288 (49), 35049-35057, 2013 | 19 | 2013 |
Inhibiting hexamer disassembly of human UDP-glucose dehydrogenase by photoactivated amino acid cross-linking G Grady, A Thelen, J Albers, T Ju, J Guo, JJ Barycki, MA Simpson Biochemistry 55 (22), 3157-3164, 2016 | 10 | 2016 |
Regulation of mTORC1-Dependent Growth Signaling by Lysosomal Cholesterol AM Thelen University of California, Berkeley, 2019 | 1 | 2019 |
Inhibiting Hexamer Disassembly of Human UDP-Glucose Dehydrogenase by Photoactivated Amino Acid Cross-Linking. Biochemistry 55 (22): 3157-3164. G Grady, A Thelen, J Albers, T Ju, J Guo, JJ Barycki, MA Simpson EXAMINATION OF HUMAN UDP-GLUCOSE DEHYDROGENASE STRUCTURE AND FUNCTION …, 2018 | | 2018 |