Human IL-2 mutein with higher antitumor efficacy than wild type IL-2 T Carmenate, A Pacios, M Enamorado, E Moreno, K Garcia-Martínez, ... The Journal of Immunology 190 (12), 6230-6238, 2013 | 139 | 2013 |
Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells T Carmenate, Y Ortíz, M Enamorado, K García-Martínez, J Avellanet, ... The Journal of Immunology, ji1700433, 2018 | 43 | 2018 |
How regulatory CD25+ CD4+ T cells impinge on tumor immunobiology? On the existence of two alternative dynamical classes of tumors K Leon, K Garcia, J Carneiro, A Lage Journal of theoretical biology 247 (1), 122-137, 2007 | 39 | 2007 |
How regulatory CD25+ CD4+ T cells impinge on tumor immunobiology: the differential response of tumors to therapies K Leon, K Garcia, J Carneiro, A Lage The Journal of Immunology 179 (9), 5659-5668, 2007 | 30 | 2007 |
Modeling the role of IL-2 in the interplay between CD4+ helper and regulatory T cells: assessing general dynamical properties K García-Martínez, K León Journal of theoretical biology 262 (4), 720-732, 2010 | 23 | 2010 |
Mathematical models of the impact of IL2 modulation therapies on T cell dynamics K León, K Garcia-Martinez, T Carmenate Frontiers in immunology 4, 439, 2013 | 22 | 2013 |
Modeling the role of IL2 in the interplay between CD4+ helper and regulatory T cells: studying the impact of IL2 modulation therapies K García-Martínez, K León International immunology 24 (7), 427-446, 2012 | 20 | 2012 |
Immunomodulatory interleukin-2 polypeptides and methods of treating melanoma KL Monzón, TC Portilla, KG Martínez, ABL Davila, SP Rodríguez, ... US Patent 8,759,486, 2014 | 17 | 2014 |
Combining computational and experimental biology to develop therapeutically valuable IL2 muteins K León, K García-Martínez, T Carmenate, G Rojas Seminars in Oncology, 2018 | 7 | 2018 |
Quantitative Contribution of IL2Rγ to the Dynamic Formation of IL2-IL2R Complexes LF Ponce, K García-Martínez, K León PloS one 11 (5), e0155684, 2016 | 6 | 2016 |
Modelación matemática de las implicaciones de la tolerancia dominante en la biología tumoral y la respuesta a terapias combinadas K León, K García, A Lage Biotecnol Apl 20, 253-7, 2003 | 3* | 2003 |
Modelación matemática del papel de la IL-2 en la dinámica de las células T: estudio del efecto de tratamientos moduladores de la IL-2 KG Martínez Anales de la Academia de Ciencias de Cuba, 2014 | 1* | 2014 |
Mathematical modeling of the implications of dominant tolerance for tumor biology and the response to combination therapy; Modelacion matematica de las implicaciones de la … K Leon, K Garcia, A Lage | 1* | 2008 |
Mathematical modeling of the implications of dominant tolerance for tumor biology and the response to combination therapy K León, K García, A Lage Biotecnología Aplicada 25 (4), 397, 2008 | 1 | 2008 |
Mathematical Models of the Role of IL-2 in the Interactions Between Helper and Regulatory CD4+ T Cells K León, K García-Martínez Mathematical Models and Immune Cell Biology, 305-337, 2011 | | 2011 |