A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition EA Traxler, Y Yao, YD Wang, KJ Woodard, R Kurita, Y Nakamura, ... Nature medicine 22 (9), 987-990, 2016 | 354 | 2016 |
Base editing of haematopoietic stem cells rescues sickle cell disease in mice GA Newby, JS Yen, KJ Woodard, T Mayuranathan, CR Lazzarotto, Y Li, ... Nature 595 (7866), 295-302, 2021 | 253 | 2021 |
Genome editing of HBG1 and HBG2 to induce fetal hemoglobin JY Métais, PA Doerfler, T Mayuranathan, DE Bauer, SC Fowler, MM Hsieh, ... Blood advances 3 (21), 3379-3392, 2019 | 141 | 2019 |
Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations KJ Woodard, PA Doerfler, KD Mayberry, A Sharma, R Levine, J Yen, ... Disease Models & Mechanisms 15 (6), dmm049463, 2022 | 9 | 2022 |
Adenosine base editing of γ-globin promoters induces fetal hemoglobin and inhibit erythroid sickling T Mayuranathan, JS Yen, GA Newby, Y Yao, SN Porter, KJ Woodard, ... Blood 136, 21-22, 2020 | 8 | 2020 |
Genome editing of HBG1 and HBG2 to induce fetal hemoglobin. Blood Adv 3: 3379–3392 JY Métais, PA Doerfler, T Mayuranathan, DE Bauer, SC Fowler, MM Hsieh, ... | 7 | 2019 |
Base editing eliminates the sickle cell mutation and pathology in hematopoietic stem cells derived erythroid cells JS Yen, GA Newby, T Mayuranathan, SN Porter, Y Yao, KJ Woodard, ... Blood 136, 13-14, 2020 | 5 | 2020 |
Genomic Characterization of Sickle Cell Mouse Models for Therapeutic Genome Editing Applications KJ Woodard The University of Tennessee Health Science Center, 2021 | 1 | 2021 |
CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies JY Metais, PA Doerfler, T Mayuranathan, DE Bauer, S Fowler, M Hsieh, ... Blood 134, 2066, 2019 | 1 | 2019 |
Base Editing Rescues Sickle Cell Disease in Human Hematopoietic Stem Cells and in Mice JS Yen, GA Newby, KJ Woodard, T Mayuranathan, C Lazzarotto, Y Li, ... MOLECULAR THERAPY 29 (4), 63-64, 2021 | | 2021 |
Genomic Characterization of the Berkeley Sickle Cell Mouse Model KJ Woodard, A Sharma, PA Doerfler, L Palmer, MJ Weiss MOLECULAR THERAPY 28 (4), 354-354, 2020 | | 2020 |
DISCOVERING NONCODING GENETIC ELEMENTS THAT REGULATE GLOBIN SYNTHESIS A Sharma, Y Yao, J Yu, Y Wang, S Tsai, K Woodard, M Weiss PEDIATRIC BLOOD & CANCER 66, 2019 | | 2019 |
Genome Editing at the Globin Locus in a Sickle Cell Disease Model KJ Woodard, PA Doerfler, T Mayuranathan, A Sharma, MJ Weiss MOLECULAR THERAPY 27 (4), 280-281, 2019 | | 2019 |
Genome Editing of Hematopoietic Stem Cells to Increase Fetal Hemoglobin in Sickle Cell Disease and beta-Thalassemia JYM Metais, Y Yao, KJ Woodard, SC Fowler, MM Wielgosz, BP Sorrentino, ... MOLECULAR THERAPY 25 (5), 343-343, 2017 | | 2017 |