The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets R Krishnakumar, WL Kraus Molecular cell 39 (1), 8-24, 2010 | 984 | 2010 |
Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes R Krishnakumar, MJ Gamble, KM Frizzell, JG Berrocal, M Kininis, ... Science 319 (5864), 819-821, 2008 | 485 | 2008 |
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway R Krishnakumar, WL Kraus Molecular cell 39 (5), 736-749, 2010 | 354 | 2010 |
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters T Zhang, JG Berrocal, KM Frizzell, MJ Gamble, ME DuMond, ... Journal of Biological Chemistry 284 (30), 20408-20417, 2009 | 285 | 2009 |
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing MJ Gamble, KM Frizzell, C Yang, R Krishnakumar, WL Kraus Genes & development 24 (1), 21-32, 2010 | 205 | 2010 |
Gene editing and CRISPR in the clinic: current and future perspectives MP Hirakawa, R Krishnakumar, JA Timlin, JP Carney, KS Butler Bioscience reports 40 (4), BSR20200127, 2020 | 193 | 2020 |
Extraction and biomolecular analysis of dermal interstitial fluid collected with hollow microneedles PR Miller, RM Taylor, BQ Tran, G Boyd, T Glaros, VH Chavez, ... Communications biology 1 (1), 173, 2018 | 176 | 2018 |
Global Analysis of Transcriptional Regulation by Poly (ADP-ribose) Polymerase-1 and Poly (ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells*♦ KM Frizzell, MJ Gamble, JG Berrocal, T Zhang, R Krishnakumar, Y Cen, ... Journal of biological chemistry 284 (49), 33926-33938, 2009 | 150 | 2009 |
Regulation of poly (ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase T Zhang, JG Berrocal, J Yao, ME DuMond, R Krishnakumar, DD Ruhl, ... Journal of Biological Chemistry 287 (15), 12405-12416, 2012 | 117 | 2012 |
Two miRNA clusters reveal alternative paths in late-stage reprogramming RJ Parchem, J Ye, RL Judson, MF LaRussa, R Krishnakumar, A Blelloch, ... Cell stem cell 14 (5), 617-631, 2014 | 97 | 2014 |
Systematic and stochastic influences on the performance of the MinION nanopore sequencer across a range of nucleotide bias R Krishnakumar, A Sinha, SW Bird, H Jayamohan, HS Edwards, ... Scientific reports 8 (1), 3159, 2018 | 81 | 2018 |
Real-time selective sequencing with RUBRIC: read until with basecall and reference-informed criteria HS Edwards, R Krishnakumar, A Sinha, SW Bird, KD Patel, MS Bartsch Scientific reports 9 (1), 11475, 2019 | 68 | 2019 |
Epigenetics of cellular reprogramming R Krishnakumar, RH Blelloch Current opinion in genetics & development 23 (5), 548-555, 2013 | 65 | 2013 |
Dynamic reorganization of the AC16 cardiomyocyte transcriptome in response to TNFα signaling revealed by integrated genomic analyses X Luo, M Chae, R Krishnakumar, CG Danko, WL Kraus BMC genomics 15, 1-22, 2014 | 45 | 2014 |
Expression of alternative Ago2 isoform associated with loss of microRNA-driven translational repression in mouse oocytes JW Freimer, R Krishnakumar, MS Cook, R Blelloch Current Biology 28 (2), 296-302. e3, 2018 | 29 | 2018 |
New candidates for regulated gene integrity revealed through precise mapping of integrative genetic elements CM Mageeney, BY Lau, JM Wagner, CM Hudson, JS Schoeniger, ... Nucleic acids research 48 (8), 4052-4065, 2020 | 26 | 2020 |
OperonSEQer: A set of machine-learning algorithms with threshold voting for detection of operon pairs using short-read RNA-sequencing data R Krishnakumar, AM Ruffing PLoS computational biology 18 (1), e1009731, 2022 | 8 | 2022 |
Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties MP Hirakawa, N Tjahjono, YK Light, AN Celebi, NN Celebi, ... Iscience 25 (2), 2022 | 5 | 2022 |
Tunable Intervalence Charge Transfer in Ruthenium Prussian Blue Analog Enables Stable and Efficient Biocompatible Artificial Synapses DA Robinson, ME Foster, CH Bennett, A Bhandarkar, ER Webster, ... Advanced Materials 35 (37), 2207595, 2023 | 4 | 2023 |
High-Density Guide RNA Tiling and Machine Learning for Designing CRISPR Interference in Synechococcus sp. PCC 7002 T Dallo, R Krishnakumar, SD Kolker, AM Ruffing ACS Synthetic Biology 12 (4), 1175-1186, 2023 | 2 | 2023 |