Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9 MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ... Cell reports 17 (5), 1453-1461, 2016 | 282 | 2016 |
Mutant NPM1 maintains the leukemic state through HOX expression L Brunetti, MC Gundry, D Sorcini, AG Guzman, YH Huang, ... Cancer cell 34 (3), 499-512. e9, 2018 | 253 | 2018 |
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A YH Huang, J Su, Y Lei, L Brunetti, MC Gundry, X Zhang, M Jeong, W Li, ... Genome biology 18, 1-11, 2017 | 220 | 2017 |
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang, Y Zhou, W Li, ... Nature communications 8 (1), 16026, 2017 | 218 | 2017 |
DNMT3A in Leukemia L Brunetti, MC Gundry, MA Goodell Cold Spring Harbor perspectives in medicine 7 (2), a030320, 2017 | 185 | 2017 |
Direct mutation analysis by high-throughput sequencing: from germline to low-abundant, somatic variants M Gundry, J Vijg Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 729 (1 …, 2012 | 115 | 2012 |
Direct, genome-wide assessment of DNA mutations in single cells M Gundry, W Li, SB Maqbool, J Vijg Nucleic acids research 40 (5), 2032-2040, 2012 | 88 | 2012 |
5-aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1 AY Maslov, M Lee, M Gundry, S Gravina, N Strogonova, C Tazearslan, ... Oncogene 31 (50), 5172-5179, 2012 | 85 | 2012 |
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity AE Pohodich, H Yalamanchili, AT Raman, YW Wan, M Gundry, S Hao, ... Elife 7, e34031, 2018 | 52 | 2018 |
Highly efficient gene disruption of murine and human hematopoietic progenitor cells by CRISPR/Cas9 L Brunetti, MC Gundry, A Kitano, D Nakada, MA Goodell JoVE (Journal of Visualized Experiments), e57278, 2018 | 43 | 2018 |
New insights into the biology of acute myeloid leukemia with mutated NPM1 L Brunetti, MC Gundry, MA Goodell International Journal of Hematology 110, 150-160, 2019 | 39 | 2019 |
Large-scale GMP-compliant CRISPR-Cas9–mediated deletion of the glucocorticoid receptor in multivirus-specific T cells R Basar, M Daher, N Uprety, E Gokdemir, A Alsuliman, E Ensley, G Ozcan, ... Blood advances 4 (14), 3357-3367, 2020 | 32 | 2020 |
Tissue-biased expansion of DNMT3A-mutant clones in a mosaic individual is associated with conserved epigenetic erosion A Tovy, JM Reyes, MC Gundry, L Brunetti, H Lee-Six, M Petljak, HJ Park, ... Cell Stem Cell 27 (2), 326-335. e4, 2020 | 29 | 2020 |
It’s all about MEis: menin-MLL inhibition eradicates NPM1-mutated and MLL-rearranged acute leukemias in mice MC Gundry, MA Goodell, L Brunetti Cancer cell 37 (3), 267-269, 2020 | 25 | 2020 |
Single-cell damagenome profiling unveils vulnerable genes and functional pathways in human genome toward DNA damage Q Zhu, Y Niu, M Gundry, C Zong Science Advances 7 (27), eabf3329, 2021 | 15 | 2021 |
Technical considerations for the use of CRISPR/Cas9 in hematology research MC Gundry, DP Dever, D Yudovich, DE Bauer, S Haas, AC Wilkinson, ... Experimental hematology 54, 4-11, 2017 | 15 | 2017 |
Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities JH Rogers, R Gupta, JM Reyes, MC Gundry, G Medrano, A Guzman, ... Blood Advances 5 (19), 3876-3890, 2021 | 12 | 2021 |
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells R Ramabadran, JH Wang, JM Reyes, AG Guzman, S Gupta, C Rosas, ... Nature cell biology 25 (4), 528-539, 2023 | 11 | 2023 |
Loss of de novo DNA methyltransferase DNMT3A impacts alternative splicing in hematopoietic stem cells R Ramabadran, J Wang, A Guzman, SM Cullen, L Brunetti, M Gundry, ... Blood 130, 1, 2017 | 7 | 2017 |
Two-pronged cell therapy for B-cell malignancies: engineering NK cells to target CD22 and redirect bystander T cells to CD19 MP Velasquez, A Szoor, CL Bonifant, A Vaidya, L Brunetti, MC Gundry, ... Blood 128 (22), 4560, 2016 | 7 | 2016 |