Molecular mechanism of anti-cancer activity of phycocyanin in triple-negative breast cancer cells M Ravi, S Tentu, G Baskar, S Rohan Prasad, S Raghavan, P Jayaprakash, ... BMC cancer 15, 1-13, 2015 | 143 | 2015 |
Epithelial-mesenchymal transition directs stem cell polarity via regulation of mitofusin MJ Wu, YS Chen, MR Kim, CC Chang, S Gampala, Y Zhang, Y Wang, ... Cell metabolism 29 (4), 993-1002. e6, 2019 | 101 | 2019 |
A graph neural network model to estimate cell-wise metabolic flux using single-cell RNA-seq data N Alghamdi, W Chang, P Dang, X Lu, C Wan, S Gampala, Z Huang, ... Genome research 31 (10), 1867-1884, 2021 | 75 | 2021 |
The multifunctional APE1 DNA repair–redox signaling protein as a drug target in human disease RA Caston, S Gampala, L Armstrong, RA Messmann, ML Fishel, ... Drug Discovery Today 26 (1), 218-228, 2021 | 69 | 2021 |
P21-activated kinase 1 (Pak1) signaling influences therapeutic outcome in pancreatic cancer S Jagadeeshan, A Subramanian, S Tentu, S Beesetti, M Singhal, ... Annals of oncology 27 (8), 1546-1556, 2016 | 45 | 2016 |
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target S Gampala, F Shah, X Lu, H Moon, O Babb, N Umesh Ganesh, ... Journal of Experimental & Clinical Cancer Research 40 (1), 251, 2021 | 26 | 2021 |
APE1/Ref-1–one target with multiple indications: emerging aspects and new directions M Mijit, R Caston, S Gampala, ML Fishel, J Fehrenbacher, MR Kelley Journal of cellular signaling 2 (3), 151, 2021 | 25 | 2021 |
Hedgehog pathway inhibitors against tumor microenvironment S Gampala, JY Yang Cells 10 (11), 3135, 2021 | 24 | 2021 |
Threonine 209 phosphorylation on RUNX3 by Pak1 is a molecular switch for its dualistic functions A Kumar, M Singhal, C Chopra, S Srinivasan, RP Surabhi, R Kanumuri, ... Oncogene 35 (37), 4857-4865, 2016 | 14 | 2016 |
Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours S Gampala, F Shah, C Zhang, SD Rhodes, O Babb, M Grimard, ... British journal of cancer 124 (9), 1566-1580, 2021 | 13 | 2021 |
Polyoxometalate entrapped caprolactam gels and their cytotoxicity study K Shakeela, G Silpa, SK Rayala, GR Rao Journal of chemical sciences 130, 1-6, 2018 | 11 | 2018 |
Basic, translational and clinical relevance of the DNA repair and redox signaling protein APE1 in human diseases S Gampala, RA Caston, ML Fishel, MR Kelley | 9 | 2020 |
Activation of AMPK sensitizes medulloblastoma to Vismodegib and overcomes Vismodegib‐resistance S Gampala, GJ Zhang, CJ Chang, JY Yang FASEB BioAdvances 3 (6), 459, 2021 | 8 | 2021 |
DHQZ‐17, a potent inhibitor of the transcription factor HNF4A, suppresses tumorigenicity of head and neck squamous cell carcinoma in vivo S Tentu, K Nandarapu, P Muthuraj, K Venkitasamy, G Venkatraman, ... Journal of Cellular Physiology 233 (3), 2613-2628, 2018 | 7 | 2018 |
Activation of the integrated stress response (ISR) pathways in response to Ref-1 inhibition in human pancreatic cancer and its tumor microenvironment M Mijit, M Boner, RA Cordova, S Gampala, E Kpenu, AJ Klunk, C Zhang, ... Frontiers in Medicine 10, 1146115, 2023 | 6 | 2023 |
RelA Is an essential target for enhancing cellular responses to the DNA Repair/Ref-1 redox signaling protein and restoring perturbated cellular redox homeostasis in mouse PDAC … M Mijit, R Wireman, L Armstrong, S Gampala, Z Hassan, C Schneeweis, ... Frontiers in Oncology 12, 826617, 2022 | 6 | 2022 |
New validated method for the determination of memantine hydrochloride content in tablet dosage forms by a high performance liquid chromatography with evaporative light … TN Rao, G Silpa, T Srinivasarao Research Journal of Pharmacy and Technology 5 (10), 1308-1311, 2012 | 3 | 2012 |
New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types S Gampala, H Moon, R Wireman, J Peil, S Kiran, DK Mitchell, K Brewster, ... Pharmacological research 201, 107092, 2024 | 2 | 2024 |
In vitro and In vivo evidence demonstrating chronic absence of Ref-1 Cysteine 65 impacts Ref-1 folding configuration, redox signaling, proliferation and metastasis in … M Mijit, E Kpenu, NN Chowdhury, S Gampala, R Wireman, S Liu, O Babb, ... Redox Biology 69, 102977, 2024 | 1 | 2024 |
Abstract PO025: Ref-1 redox function identified as mitochondrial metabolic regulator in pancreatic cancer cells but not in CAFs S Gampala, F Shah, X Lu, H Moon, GE Sandusky, E Hulsey, AL Mosley, ... Cancer Research 81 (5_Supplement), PO025-PO025, 2021 | 1 | 2021 |