关注
Suzanne B.R. Jacobs
Suzanne B.R. Jacobs
Research Scientist, The Broad Institutue of Harvard & MIT
在 broadinstitute.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
AL Williams, SBR Jacobs, H Moreno-Macías, A Huerta-Chagoya, ...
Nature 506 (7486), 97-101, 2014
5632014
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
J Flannick, G Thorleifsson, NL Beer, SBR Jacobs, N Grarup, NP Burtt, ...
Nature genetics 46 (4), 357-363, 2014
5392014
Genome-wide meta-analysis identifies new susceptibility loci for migraine
V Anttila, BS Winsvold, P Gormley, T Kurth, F Bettella, G McMahon, ...
Nature genetics 45 (8), 912-917, 2013
4642013
Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population
K Estrada, I Aukrust, L Bjørkhaug, NP Burtt, JM Mercader, H García-Ortiz, ...
Jama 311 (22), 2305-2314, 2014
2732014
Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in the LβT2 pituitary gonadotrope cell model
F Pernasetti, VV Vasilyev, SB Rosenberg, JS Bailey, HJ Huang, WL Miller, ...
Endocrinology 142 (6), 2284-2295, 2001
252*2001
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ...
Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014
1772014
A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone β gene by gonadotropin-releasing hormone
D Coss, SBR Jacobs, CE Bender, PL Mellon
Journal of Biological Chemistry 279 (1), 152-162, 2004
1712004
Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms
V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ...
Cell 170 (1), 199-212. e20, 2017
1552017
The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation
S Basak, SBR Jacobs, AJ Krieg, N Pathak, Q Zeng, P Kaldis, AJ Giaccia, ...
Molecular cell 30 (3), 303-314, 2008
1412008
Reactivation of proliferin gene expression is associated with increased angiogenesis in a cell culture model of fibrosarcoma tumor progression
DJ Toft, SB Rosenberg, G Bergers, O Volpert, DIH Linzer
Proceedings of the National Academy of Sciences 98 (23), 13055-13059, 2001
1042001
Polyunsaturated fatty acid desaturation is a mechanism for glycolytic NAD+ recycling
W Kim, A Deik, C Gonzalez, ME Gonzalez, F Fu, M Ferrari, ...
Cell metabolism 29 (4), 856-870. e7, 2019
1032019
Transcriptional activation of the ovine follicle-stimulating hormone-β gene by gonadotropin-releasing hormone involves multiple signal transduction pathways
VV Vasilyev, F Pernasetti, SB Rosenberg, MJ Barsoum, DA Austin, ...
Endocrinology 143 (5), 1651-1659, 2002
752002
Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse follicle-stimulating hormone-β gene
SBR Jacobs, D Coss, SM McGillivray, PL Mellon
Molecular Endocrinology 17 (8), 1470-1483, 2003
732003
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes
JM Mercader, RG Liao, AD Bell, Z Dymek, K Estrada, T Tukiainen, ...
Diabetes 66 (11), 2903-2914, 2017
622017
An Otx-related homeodomain protein binds an LHβ promoter element important for activation during gonadotrope maturation
SB Rosenberg, PL Mellon
Molecular Endocrinology 16 (6), 1280-1298, 2002
572002
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
A Manning, HM Highland, J Gasser, X Sim, T Tukiainen, P Fontanillas, ...
Diabetes 66 (7), 2019-2032, 2017
542017
Siva is an apoptosis-selective p53 target gene important for neuronal cell death
SBR Jacobs, S Basak, JI Murray, N Pathak, LD Attardi
Cell Death & Differentiation 14 (7), 1374-1385, 2007
492007
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits
MC Costanzo, M von Grotthuss, J Massung, D Jang, L Caulkins, ...
Cell metabolism 35 (4), 695-710. e6, 2023
452023
Loss of the Desmosomal Component Perp Impairs Wound Healing In Vivo
VG Beaudry, RA Ihrie, SBR Jacobs, B Nguyen, N Pathak, E Park, ...
Dermatology Research and Practice 2010 (1), 759731, 2010
342010
The p53 Target Gene SIVA Enables Non–Small Cell Lung Cancer Development
JL Van Nostrand, A Brisac, SS Mello, SBR Jacobs, R Luong, LD Attardi
Cancer discovery 5 (6), 622-635, 2015
272015
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