| DNA repair pathways as targets for cancer therapy T Helleday, E Petermann, C Lundin, B Hodgson, RA Sharma Nature Reviews Cancer 8 (3), 193-204, 2008 | 2037 | 2008 |
| Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair E Petermann, ML Orta, N Issaeva, N Schultz, T Helleday Molecular cell 37 (4), 492-502, 2010 | 909 | 2010 |
| PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination HE Bryant, E Petermann, N Schultz, AS Jemth, O Loseva, N Issaeva, ... The EMBO journal 28 (17), 2601-2615, 2009 | 720 | 2009 |
| ATR‐dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling T Stiff, SA Walker, K Cerosaletti, AA Goodarzi, E Petermann, ... The EMBO journal 25 (24), 5775-5782, 2006 | 468 | 2006 |
| Pathways of mammalian replication fork restart E Petermann, T Helleday Nature reviews Molecular cell biology 11 (10), 683-687, 2010 | 432 | 2010 |
| Mechanisms of oncogene-induced replication stress: jigsaw falling into place P Kotsantis, E Petermann, SJ Boulton Cancer discovery 8 (5), 537-555, 2018 | 371 | 2018 |
| Chk1 promotes replication fork progression by controlling replication initiation E Petermann, M Woodcock, T Helleday Proceedings of the National Academy of Sciences 107 (37), 16090-16095, 2010 | 334 | 2010 |
| Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress RM Jones, O Mortusewicz, I Afzal, M Lorvellec, P García, T Helleday, ... Oncogene 32 (32), 3744-3753, 2013 | 319 | 2013 |
| Increased global transcription activity as a mechanism of replication stress in cancer P Kotsantis, LM Silva, S Irmscher, RM Jones, L Folkes, N Gromak, ... Nature communications 7 (1), 13087, 2016 | 303 | 2016 |
| ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells M Kwok, N Davies, A Agathanggelou, E Smith, C Oldreive, E Petermann, ... Blood, The Journal of the American Society of Hematology 127 (5), 582-595, 2016 | 286 | 2016 |
| Chk1 regulates the density of active replication origins during the vertebrate S phase A Maya‐Mendoza, E Petermann, DAF Gillespie, KW Caldecott, ... The EMBO journal 26 (11), 2719-2731, 2007 | 272 | 2007 |
| Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase E Petermann, A Maya-Mendoza, G Zachos, DAF Gillespie, DA Jackson, ... Molecular and cellular biology 26 (8), 3319-3326, 2006 | 221 | 2006 |
| PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation GE Ronson, AL Piberger, MR Higgs, AL Olsen, GS Stewart, PJ McHugh, ... Nature communications 9 (1), 746, 2018 | 211 | 2018 |
| Replication fork dynamics and the DNA damage response RM Jones, E Petermann Biochemical Journal 443 (1), 13-26, 2012 | 175 | 2012 |
| Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase E Petermann, KW Caldecott Cell cycle 5 (19), 2203-2209, 2006 | 171 | 2006 |
| Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids E Petermann, L Lan, L Zou Nature Reviews Molecular Cell Biology 23 (8), 521-540, 2022 | 153 | 2022 |
| Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control D Wilsker, E Petermann, T Helleday, F Bunz Proceedings of the National Academy of Sciences 105 (52), 20752-20757, 2008 | 151 | 2008 |
| Claspin promotes normal replication fork rates in human cells E Petermann, T Helleday, KW Caldecott Molecular biology of the cell 19 (6), 2373-2378, 2008 | 128 | 2008 |
| ATP-dependent selection between single nucleotide and long patch base excision repair E Petermann, M Ziegler, SL Oei DNA repair 2 (10), 1101-1114, 2003 | 107 | 2003 |
| BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia D Da Costa, A Agathanggelou, T Perry, V Weston, E Petermann, ... Blood cancer journal 3 (7), e126-e126, 2013 | 97 | 2013 |
Thomas HelledayKarolinska Institutet在 ki.se 的电子邮件经过验证
