The Cdt1 protein is required to license DNA for replication in fission yeast H Nishitani, Z Lygerou, T Nishimoto, P Nurse Nature 404 (6778), 625-628, 2000 | 640 | 2000 |
Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis H Nishitani, N Sugimoto, V Roukos, Y Nakanishi, M Saijo, C Obuse, ... The EMBO journal 25 (5), 1126-1136, 2006 | 442 | 2006 |
Control of DNA replication licensing in a cell cycle H Nishitani, Z Lygerou Genes to Cells 7 (6), 523-534, 2002 | 360 | 2002 |
The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase H Nishitani, S Taraviras, Z Lygerou, T Nishimoto Journal of Biological Chemistry 276 (48), 44905-44911, 2001 | 321 | 2001 |
Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitro Z Lygerou, C Allmang, D Tollervey, B Séraphin Science 272 (5259), 268-270, 1996 | 320 | 1996 |
The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Z Lygerou, P Mitchell, E Petfalski, B Séraphin, D Tollervey Genes & development 8 (12), 1423-1433, 1994 | 245 | 1994 |
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior M Liontos, M Koutsami, M Sideridou, K Evangelou, D Kletsas, B Levy, ... Cancer research 67 (22), 10899-10909, 2007 | 244 | 2007 |
Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor … P Karakaidos, S Taraviras, LV Vassiliou, P Zacharatos, NG Kastrinakis, ... The American journal of pathology 165 (4), 1351-1365, 2004 | 222 | 2004 |
Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region H Nishitani, Z Lygerou, T Nishimoto Journal of Biological Chemistry 279 (29), 30807-30816, 2004 | 185 | 2004 |
easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data MA Rapsomaniki, P Kotsantis, IE Symeonidou, NN Giakoumakis, ... Bioinformatics 28 (13), 1800-1801, 2012 | 173 | 2012 |
Cdt1 and geminin are down‐regulated upon cell cycle exit and are over‐expressed in cancer‐derived cell lines G Xouri, Z Lygerou, H Nishitani, V Pachnis, P Nurse, S Taraviras European journal of biochemistry 271 (16), 3368-3378, 2004 | 140 | 2004 |
EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data G Koulouras, A Panagopoulos, MA Rapsomaniki, NN Giakoumakis, ... Nucleic acids research 46 (W1), W467-W472, 2018 | 131 | 2018 |
Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication SK Yanow, Z Lygerou, P Nurse The EMBO journal, 2001 | 125 | 2001 |
hPop1: an autoantigenic protein subunit shared by the human RNase P and RNase MRP ribonucleoproteins. Z Lygerou, H Pluk, WJ Van Venrooij, B Seraphin The EMBO journal 15 (21), 5936-5948, 1996 | 118 | 1996 |
Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche C Kyrousi, M Arbi, GA Pilz, DE Pefani, ME Lalioti, J Ninkovic, M Götz, ... Development 142 (21), 3661-3674, 2015 | 104 | 2015 |
The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs Z Lygerou, C Conesa, P Lesage, RN Swanson, A Ruet, M Carlson, ... Nucleic acids research 22 (24), 5332-5340, 1994 | 101 | 1994 |
Replication licensing aberrations, replication stress, and genomic instability M Petropoulos, SC Tsaniras, S Taraviras, Z Lygerou Trends in biochemical sciences 44 (9), 752-764, 2019 | 95 | 2019 |
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing V De Marco, PJ Gillespie, A Li, N Karantzelis, E Christodoulou, ... Proceedings of the National Academy of Sciences 106 (47), 19807-19812, 2009 | 95 | 2009 |
Stochastic hybrid modeling of DNA replication across a complete genome J Lygeros, K Koutroumpas, S Dimopoulos, I Legouras, P Kouretas, ... Proceedings of the National Academy of Sciences 105 (34), 12295-12300, 2008 | 95 | 2008 |
Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world? SC Tsaniras, N Kanellakis, IE Symeonidou, P Nikolopoulou, Z Lygerou, ... Seminars in cell & developmental biology 30, 174-180, 2014 | 89 | 2014 |