Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13273* | 2021 |
Superoxide is the major reactive oxygen species regulating autophagy Y Chen, MB Azad, SB Gibson Cell Death & Differentiation 16 (7), 1040-1052, 2009 | 891 | 2009 |
Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment MB Azad, Y Chen, SB Gibson Antioxidants & redox signaling 11 (4), 777-790, 2009 | 818 | 2009 |
The regulation of autophagy–unanswered questions Y Chen, DJ Klionsky Journal of cell science 124 (2), 161-170, 2011 | 805 | 2011 |
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells Y Chen, E McMillan-Ward, J Kong, SJ Israels, SB Gibson Cell Death & Differentiation 15 (1), 171-182, 2008 | 757 | 2008 |
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species Y Chen, E McMillan-Ward, J Kong, SJ Israels, SB Gibson Journal of cell science 120 (23), 4155-4166, 2007 | 526 | 2007 |
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells S Ma, ES Henson, Y Chen, SB Gibson Cell death & disease 7 (7), e2307-e2307, 2016 | 504 | 2016 |
Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3 MB Azad, Y Chen, ES Henson, J Cizeau, E McMillan-Ward, SJ Israels, ... Autophagy 4 (2), 195-204, 2008 | 426 | 2008 |
Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation L Li, Y Chen, SB Gibson Cellular signalling 25 (1), 50-65, 2013 | 338 | 2013 |
Is mitochondrial generation of reactive oxygen species a trigger for autophagy? Y Chen, SB Gibson Autophagy 4 (2), 246-248, 2008 | 275 | 2008 |
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation F Liu, F Fang, H Yuan, D Yang, Y Chen, L Williams, SA Goldstein, ... Journal of Bone and Mineral Research 28 (11), 2414-2430, 2013 | 221 | 2013 |
Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells S Ma, RF Dielschneider, ES Henson, W Xiao, TR Choquette, ... PLOS ONE 12 (8), e0182921, 2017 | 168 | 2017 |
Methods for detecting autophagy and determining autophagy-induced cell death Y Chen, MB Azad, SB Gibson Canadian journal of physiology and pharmacology 88 (3), 285-295, 2010 | 154 | 2010 |
EGFR family members’ regulation of autophagy is at a crossroads of cell survival and death in cancer E Henson, Y Chen, S Gibson Cancers 9 (4), 27, 2017 | 102 | 2017 |
Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia Y Chen, ES Henson, W Xiao, D Huang, EM McMillan-Ward, SJ Israels, ... Autophagy 12 (6), 1029-1046, 2016 | 100 | 2016 |
Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling Y Chen, H Wei, F Liu, JL Guan Journal of Biological Chemistry 289 (2), 1164-1173, 2014 | 44 | 2014 |
Three dimensions of autophagy in regulating tumor growth: cell survival/death, cell proliferation, and tumor dormancy Y Chen, SB Gibson Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (12), 166265, 2021 | 22 | 2021 |
Bcl-2 family member Mcl-1 expression is reduced under hypoxia by the E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells Y Chen, ES Henson, W Xiao, E Shome, MB Azad, TR Burton, M Queau, ... Cancer Biology & Therapy 17 (6), 604-613, 2016 | 22 | 2016 |
The role of cellular prion protein in cancer biology: a potential therapeutic target M Ding, Y Chen, Y Lang, L Cui Frontiers in Oncology 11, 742949, 2021 | 12 | 2021 |
Erb-b2 receptor tyrosine kinase 2 (ERBB2) promotes ATG12-dependent autophagy contributing to treatment resistance of breast cancer cells Y Chen, R Wang, S Huang, ES Henson, J Bi, SB Gibson Cancers 13 (5), 1038, 2021 | 12 | 2021 |