Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities B Hong, PJ van den Heuvel, V V Prabhu, S Zhang, W S El-Deiry Current drug targets 15 (1), 80-89, 2014 | 289 | 2014 |
Small-molecule NSC59984 restores p53 pathway signaling and antitumor effects against colorectal cancer via p73 activation and degradation of mutant p53 S Zhang, L Zhou, B Hong, APJ van den Heuvel, VV Prabhu, NA Warfel, ... Cancer research 75 (18), 3842-3852, 2015 | 112 | 2015 |
Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53 B Hong, VV Prabhu, S Zhang, APJ van den Heuvel, DT Dicker, ... Cancer research 74 (4), 1153-1165, 2014 | 92 | 2014 |
Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells VWY Lui, DMS Yau, EYL Wong, YK Ng, CPK Lau, Y Ho, JPL Chan, ... Carcinogenesis 30 (12), 2085-2094, 2009 | 91 | 2009 |
STAT3 activation contributes directly to Epstein‐Barr virus–mediated invasiveness of nasopharyngeal cancer cells in vitro VWY Lui, EYL Wong, Y Ho, B Hong, SCC Wong, Q Tao, GCG Choi, ... International journal of cancer 125 (8), 1884-1893, 2009 | 88 | 2009 |
Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death VWY Lui, EYL Wong, K Ho, PKS Ng, CPY Lau, SKW Tsui, CM Tsang, ... Oncogene 30 (9), 1127-1134, 2011 | 69 | 2011 |
Targeting tumor hypoxia in nasopharyngeal carcinoma B Hong, VWY Lui, M Hashiguchi, EP Hui, ATC Chan Head & neck 35 (1), 133-145, 2013 | 65 | 2013 |
Small-molecule prodigiosin restores p53 tumor suppressor activity in chemoresistant colorectal cancer stem cells via c-Jun-mediated ΔNp73 inhibition and p73 activation VV Prabhu, B Hong, JE Allen, S Zhang, AR Lulla, DT Dicker, WS El-Deiry Cancer research 76 (7), 1989-1999, 2016 | 64 | 2016 |
Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents W Wang, JN Gallant, SI Katz, NG Dolloff, CD Smith, J Abdulghani, ... Cancer biology & therapy 12 (3), 229-238, 2011 | 56 | 2011 |
Therapeutic targeting of the p53 pathway in cancer stem cells VV Prabhu, JE Allen, B Hong, S Zhang, H Cheng, WS El-Deiry Expert opinion on therapeutic targets 16 (12), 1161-1174, 2012 | 50 | 2012 |
An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl) cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis … VWY Lui, CPY Lau, CSF Cheung, K Ho, MHL Ng, SH Cheng, B Hong, ... Biochemical pharmacology 79 (12), 1772-1780, 2010 | 47 | 2010 |
JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer H Wang, B Hong, X Li, K Deng, H Li, VWY Lui, W Lin Oncotarget 8 (49), 86312, 2017 | 46 | 2017 |
Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation H Cheng, B Hong, L Zhou, JE Allen, G Tai, R Humphreys, DT Dicker, ... Cell cycle 11 (17), 3312-3323, 2012 | 32 | 2012 |
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1 B Hong, VWY Lui, EP Hui, Y Lu, HSY Leung, EYL Wong, SH Cheng, ... Biochemical pharmacology 79 (6), 842-852, 2010 | 28 | 2010 |
Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation B Hong, VWY Lui, EP Hui, MHL Ng, SH Cheng, FL Sung, CM Tsang, ... Investigational new drugs 29, 401-410, 2011 | 26 | 2011 |
Transcription factor fork head regulates the promoter of diapause hormone gene in the cotton bollworm, Helicoverpa armigera, and the modification of SUMOylation B Bao, B Hong, QL Feng, WH Xu Insect Biochemistry and Molecular Biology 41 (9), 670-679, 2011 | 23 | 2011 |
Liquid biopsies to distinguish malignant from benign pulmonary nodules R Tao, W Cao, F Zhu, J Nie, H Wang, L Wang, P Liu, H Chen, B Hong, ... Thoracic Cancer 12 (11), 1647-1655, 2021 | 17 | 2021 |
A high-throughput drug screen identifies auranofin as a potential sensitizer of cisplatin in small cell lung cancer X Liu, W Wang, Y Yin, M Li, H Li, H Xiang, A Xu, X Mei, B Hong, W Lin Investigational New Drugs 37, 1166-1176, 2019 | 15 | 2019 |
Protein–DNA interactions in the promoter region of the gene encoding diapause hormone and pheromone biosynthesis activating neuropeptide of the cotton bollworm, Helicoverpa … B Hong, ZF Zhang, SM Tang, YZ Yi, TY Zhang, WH Xu Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1759 (3-4 …, 2006 | 15 | 2006 |
FGF8b oncogene mediates proliferation and invasion of Epstein–Barr virus-associated nasopharyngeal carcinoma cells: implication for viral-mediated FGF8b upregulation VWY Lui, D Yau, CSF Cheung, SCC Wong, AKC Chan, Q Zhou, ... Oncogene 30 (13), 1518-1530, 2011 | 14 | 2011 |