Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy S Goulart, MIG Moritz, KL Lang, R Liz, EP Schenkel, TS Fröde Journal of Ethnopharmacology 113 (2), 346-353, 2007 | 70 | 2007 |
Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives KL Lang, IT Silva, LA Zimmermann, VR Machado, MR Teixeira, MI Lapuh, ... Bioorganic & medicinal chemistry 20 (9), 3016-3030, 2012 | 61 | 2012 |
Drug repositioning: concept, classification, methodology, and importance in rare/orphans and neglected diseases EAM de Oliveira, KL Lang Journal of Applied Pharmaceutical Science 8 (8), 157-165, 2018 | 45 | 2018 |
In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B IT Silva, A Carvalho, KL Lang, SE Dudek, D Masemann, FJ Duran, ... PloS one 10 (2), e0117794, 2015 | 45* | 2015 |
Physico-chemical solid-state characterization of omeprazole sodium: thermal, spectroscopic and crystallinity studies FS Murakami, KL Lang, C Mendes, AP Cruz, MAS Carvalho Filho, ... Journal of pharmaceutical and biomedical analysis 49 (1), 72-80, 2009 | 36 | 2009 |
Synergistic antiproliferative effects of a new cucurbitacin B derivative and chemotherapy drugs on lung cancer cell line A549 LL Marostica, IT Silva, JM Kratz, L Persich, FC Geller, KL Lang, MSB Caro, ... Chemical Research in Toxicology 28 (10), 1949-1960, 2015 | 35 | 2015 |
Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model LL Marostica, ALB de Barros, J Oliveira, BS Salgado, GD Cassali, ... Toxicology and Applied Pharmacology 329, 272-281, 2017 | 33 | 2017 |
Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549 IT Silva, FC Geller, L Persich, SE Dudek, KL Lang, MSB Caro, FJ Durán, ... Investigational New Drugs 34, 139-148, 2016 | 31 | 2016 |
Investigação das atividades alelopática e antimicrobiana de Mikania laevigata (Asteraceae) obtida de cultivos hidropônico e tradicional L Baratto, KL Lang, DC Vanz, FH Reginatto, JB Oliveira, M Falkenberg Revista Brasileira de Farmacognosia 18, 577-582, 2008 | 31 | 2008 |
Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line KL Lang, IT Silva, VR Machado, LA Zimmermann, MSB Caro, ... Journal of Molecular Graphics and Modelling 48, 70-79, 2014 | 21 | 2014 |
Efeitos farmacológicos do extrato aquoso de Solidago chilensis Meyen em camundongos FL Assini, EJ Fabrício, KL Lang Revista Brasileira de Plantas Medicinais 15, 130-134, 2013 | 16 | 2013 |
Semi-Synthesis of new glycosidic triazole derivatives of dihydrocucurbitacin B ALM Morotti, KL Lang, I Carvalho, EP Schenkel, LSC Bernardes Tetrahedron Letters 56 (2), 303-307, 2015 | 15 | 2015 |
New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. KL Lang, T da Rosa Guimarães, VR Machado, LA Zimmermann, IT Silva, ... Planta medica 77 (14), 1648-1651, 2011 | 15 | 2011 |
Chemical modification produces species-specific changes in cucurbitacin antifeedant effect KL Lang, E Deagosto, LA Zimmermann, VR Machado, ... Journal of agricultural and food chemistry 61 (23), 5534-5539, 2013 | 14 | 2013 |
Cytotoxic activity of semi-synthetic derivatives of elatol and isoobtusol KL Lang, IT Silva, LA Zimmermann, C Lhullier, MV Mañalich Arana, ... Marine Drugs 10 (10), 2254-2264, 2012 | 10 | 2012 |
Steroids from the red alga Acanthophora spicifera KL Lang, JA Palermo, M Falkenberg, EP Schenkel Pergamon-Elsevier Science Ltd, 2007 | 10 | 2007 |
Evaluation of in vitro Antifungal Activity of Xylosma prockia (Turcz.) Turcz. (Salicaceae) Leaves Against Cryptococcus spp. MLC Folly, GF Ferreira, MR Salvador, AA Sathler, GF Da Silva, ... Frontiers in Microbiology 10, 3114, 2020 | 7 | 2020 |
Proliferative inhibition and apoptotic mechanism on human non-small-cell lung Cancer (A549 Cells) of a novel cucurbitacin from Wilbrandia ebracteata Cogn IT Silva, MR Teixeira, KL Lang, TR Guimarães, SE Dudek, FJ Duran, ... Science Alert, 2013 | 7 | 2013 |
Identification of Undeclared Synthetic Drugs in Herbal Products Commercialized in Brazil: The``Indiano Talun''Case MIG Moritz, KL Lang, L Baratto, MSB Caro, M Falkenberg, EP Schenkel Latin American Journal of Pharmacy 27 (2), 274, 2008 | 7 | 2008 |
Copalic acid: occurrence, chemistry, and biological activities VG Medeiros, FJ Durán, KL Lang Revista Brasileira de Farmacognosia 31 (4), 375-386, 2021 | 5 | 2021 |