MicroRNA-125a and-b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD ACY Hsu, K Dua, MR Starkey, TJ Haw, PM Nair, K Nichol, N Zammit, ... JCI insight 2 (7), 2017 | 113 | 2017 |
Human islets express a marked proinflammatory molecular signature prior to transplantation MJ Cowley, A Weinberg, NW Zammit, SN Walters, WJ Hawthorne, ... Cell transplantation 21 (9), 2063-2078, 2012 | 98 | 2012 |
Nuclear factor κB–inducing kinase activation as a mechanism of pancreatic β cell failure in obesity EK Malle, NW Zammit, SN Walters, YC Koay, J Wu, BM Tan, ... The Journal of experimental medicine 212 (8), 1239, 2015 | 62 | 2015 |
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, ... Nature immunology 20 (10), 1299-1310, 2019 | 55 | 2019 |
β cell replacement therapy: the next 10 years C Schuetz, T Anazawa, SE Cross, L Labriola, RPH Meier, RR Redfield III, ... Transplantation 102 (2), 215-229, 2018 | 48 | 2018 |
Spatial and temporal control of CRISPR-Cas9-mediated gene editing delivered via a light-triggered liposome system YA Aksoy, B Yang, W Chen, T Hung, RP Kuchel, NW Zammit, ST Grey, ... ACS applied materials & interfaces 12 (47), 52433-52444, 2020 | 46 | 2020 |
A20 as an immune tolerance factor can determine islet transplant outcomes NW Zammit, SN Walters, KL Seeberger, PJ O’Connell, GS Korbutt, ... JCI insight 4 (21), 2019 | 40 | 2019 |
Acute phase proteins are major clients for the chaperone action of α2-macroglobulin in human plasma AR Wyatt, MR Wilson Cell Stress and Chaperones 18 (2), 161-170, 2013 | 40 | 2013 |
Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells BM Tan, NW Zammit, AO Yam, R Slattery, SN Walters, E Malle, ST Grey Diabetologia 56, 520-532, 2013 | 30 | 2013 |
Low-Dose Rapamycin Unmasks the Protective Potential of Targeting Intragraft NF-κB for Islet Transplants. NW Zammit, BM Tan, SN Walters, D Liuwantara, JE Villanueva, ST Grey Cell transplantation, 2013 | 19 | 2013 |
TRAF2 regulates peripheral CD8+ T‐cell and NKT‐cell homeostasis by modulating sensitivity to IL‐15 JE Villanueva, EK Malle, S Gardam, PA Silveira, NW Zammit, SN Walters, ... European Journal of Immunology 45 (6), 1820-1831, 2015 | 17 | 2015 |
Emerging roles for A20 in islet biology and pathology NW Zammit, ST Grey The Multiple Therapeutic Targets of A20, 141-162, 2014 | 15 | 2014 |
The retroelement Lx9 puts a brake on the immune response to virus infection N Bartonicek, R Rouet, J Warren, C Loetsch, GS Rodriguez, S Walters, ... Nature 608 (7924), 757-765, 2022 | 9 | 2022 |
Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice JE Villanueva, SN Walters, M Saito, EK Malle, NW Zammit, KA Watson, ... Diabetologia 60, 679-689, 2017 | 8 | 2017 |
A zebrafish functional genomics model to investigate the role of human A20 variants in vivo D Cultrone, NW Zammit, E Self, B Postert, JZR Han, J Bailey, J Warren, ... Scientific reports 10 (1), 19085, 2020 | 6 | 2020 |
Equipping the islet graft for self defence: targeting nuclear factor κB and implications for tolerance NW Zammit, ST Grey Current Opinion in Organ Transplantation 23 (1), 97-105, 2018 | 6 | 2018 |
TNFAIP3 reduction-of-function drives female infertility and CNS inflammation NW Zammit, J McDowell, J Warren, W Muskovic, J Gamble, YC Shi, ... Frontiers in Immunology 13, 811525, 2022 | 5 | 2022 |
Selection of a novel AAV2/TNFAIP3 vector for local suppression of islet xenograft inflammation NW Zammit, KL Seeberger, J Zamerli, SN Walters, L Lisowski, GS Korbutt, ... Xenotransplantation 28 (3), e12669, 2021 | 5 | 2021 |
RELA governs a network of islet-specific metabolic genes necessary for beta cell function NW Zammit, YY Wong, SN Walters, J Warren, SC Barry, ST Grey Diabetologia 66 (8), 1516-1531, 2023 | 4 | 2023 |
The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury NM Rogers, N Zammit, D Nguyen-Ngo, Y Souilmi, N Minhas, DN Meijles, ... Kidney International 103 (6), 1105-1119, 2023 | 3 | 2023 |