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András Váradi
András Váradi
在 cumc.columbia.edu 的电子邮件经过验证
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引用次数
引用次数
年份
Mitragynine/corynantheidine pseudoindoxyls as opioid analgesics with mu agonism and delta antagonism, which do not recruit β-arrestin-2
A Váradi, GF Marrone, TC Palmer, A Narayan, MR Szabó, V Le Rouzic, ...
Journal of medicinal chemistry 59 (18), 8381-8397, 2016
3152016
Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators
AC Kruegel, MM Gassaway, A Kapoor, A Váradi, S Majumdar, M Filizola, ...
Journal of the American Chemical Society 138 (21), 6754-6764, 2016
3082016
Isocyanide-based multicomponent reactions for the synthesis of heterocycles
A Váradi, TC Palmer, R Notis Dardashti, S Majumdar
Molecules 21 (1), 19, 2015
1662015
Detection and identification of the new potential synthetic cannabinoids 1-pentyl-3-(2-iodobenzoyl) indole and 1-pentyl-3-(1-adamantoyl) indole in seized bulk powders in Hungary
P Jankovics, A Váradi, L Tölgyesi, S Lohner, J Németh-Palotás, J Balla
Forensic science international 214 (1-3), 27-32, 2012
1062012
Identification and characterization of the new designer drug 4′-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography–tandem mass spectrometry (LC–MS/MS …
P Jankovics, A Váradi, L Tölgyesi, S Lohner, J Németh-Palotás, ...
Forensic science international 210 (1-3), 213-220, 2011
992011
Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior
A Váradi, GF Marrone, SO Eans, ML Ganno, JJ Subrath, V Le Rouzic, ...
ACS chemical neuroscience 6 (11), 1813-1824, 2015
612015
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ...
Elife 10, e56519, 2021
562021
Synthesis of carfentanil amide opioids using the Ugi multicomponent reaction
A Váradi, TC Palmer, N Haselton, D Afonin, JJ Subrath, V Le Rouzic, ...
ACS chemical neuroscience 6 (9), 1570-1577, 2015
532015
Oxidative metabolism as a modulator of kratom’s biological actions
S Chakraborty, R Uprety, ST Slocum, T Irie, V Le Rouzic, X Li, LL Wilson, ...
Journal of medicinal chemistry 64 (22), 16553-16572, 2021
402021
A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle
B Racz, A Varadi, J Kong, R Allikmets, PG Pearson, G Johnson, CL Cioffi, ...
Journal of Biological Chemistry 293 (29), 11574-11588, 2018
402018
A novel µ-opioid receptor ligand with high in vitro and in vivo agonist efficacy
E Lacko, A Varadi, R Rapavi, F Zador, P Riba, S Benyhe, A Borsodi, ...
Current medicinal chemistry 19 (27), 4699-4707, 2012
322012
Three-component coupling approach for the synthesis of diverse heterocycles utilizing reactive nitrilium trapping
A Varadi, TC Palmer, PR Notis, GN Redel-Traub, D Afonin, JJ Subrath, ...
Organic letters 16 (6), 1668-1671, 2014
282014
Design, synthesis, and preclinical efficacy of novel nonretinoid antagonists of retinol-binding protein 4 in the mouse model of hepatic steatosis
CL Cioffi, B Racz, A Varadi, EE Freeman, MP Conlon, P Chen, L Zhu, ...
Journal of medicinal chemistry 62 (11), 5470-5500, 2019
272019
Mild, Pd-catalyzed stannylation of radioiodination targets
JE Pickett, A Váradi, TC Palmer, SG Grinnell, JM Schrock, GW Pasternak, ...
Bioorganic & medicinal chemistry letters 25 (8), 1761-1764, 2015
252015
New morphine analogs produce peripheral antinociception within a certain dose range of their systemic administration
E Lackó, P Riba, Z Giricz, A Váradi, L Cornic, M Balogh, K Király, ...
Journal of Pharmacology and Experimental Therapeutics 359 (1), 171-181, 2016
232016
Synthesis and configurational assignment of 1, 2-dihydroimidazo [5, 1-b] quinazoline-3, 9-diones: novel NMDA receptor antagonists
A Váradi, P Horváth, T Kurtán, A Mándi, G Tóth, A Gergely, J Kökösi
Tetrahedron 68 (50), 10365-10371, 2012
232012
Novel 6β-acylaminomorphinans with analgesic activity
A Váradi, S Hosztafi, V Le Rouzic, G Tóth, Á Urai, B Noszál, ...
European journal of medicinal chemistry 69, 786-789, 2013
222013
Sulfate esters of morphine derivatives: Synthesis and characterization
A Váradi, A Gergely, S Béni, P Jankovics, B Noszál, S Hosztafi
European journal of pharmaceutical sciences 42 (1-2), 65-72, 2011
222011
Genetic dissociation of morphine analgesia from hyperalgesia in mice
GF Marrone, V Le Rouzic, A Varadi, J Xu, AM Rajadhyaksha, S Majumdar, ...
Psychopharmacology 234, 1891-1900, 2017
212017
The mixed kappa and delta opioid receptor agonist, MP1104, attenuates chemotherapy-induced neuropathic pain
DV Atigari, KF Paton, R Uprety, A Váradi, AF Alder, B Scouller, JH Miller, ...
Neuropharmacology 185, 108445, 2021
152021
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