Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance CW Lu, SC Lin, KF Chen, YY Lai, SJ Tsai Journal of Biological Chemistry 283 (42), 28106-28114, 2008 | 392 | 2008 |
Light-dependent interactions between the Drosophila circadian clock factors cryptochrome, jetlag, and timeless N Peschel, KF Chen, G Szabo, R Stanewsky Current Biology 19 (3), 241-247, 2009 | 265 | 2009 |
Aberrant expression of leptin in human endometriotic stromal cells is induced by elevated levels of hypoxia inducible factor-1α MH Wu, KF Chen, SC Lin, CW Lgu, SJ Tsai The American journal of pathology 170 (2), 590-598, 2007 | 148 | 2007 |
A Wake-Promoting Circadian Output Circuit in Drosophila A Lamaze, P Krätschmer, KF Chen, S Lowe, JEC Jepson Current Biology 28 (19), 3098-3105. e3, 2018 | 106 | 2018 |
Transcriptional repression of human cad gene by hypoxia inducible factor-1α KF Chen, YY Lai, HS Sun, SJ Tsai Nucleic acids research 33 (16), 5190-5198, 2005 | 106 | 2005 |
Central and peripheral circadian clocks and their role in Alzheimer's disease R Chauhan, KF Chen, BA Kent, DC Crowther Disease Models & Mechanisms 10 (10), 1187-1199, 2017 | 66 | 2017 |
The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease KF Chen, B Possidente, DA Lomas, DC Crowther Disease models & mechanisms 7 (4), 445-458, 2014 | 63 | 2014 |
QUASIMODO, a Novel GPI-anchored zona pellucida protein involved in light input to the Drosophila circadian clock KF Chen, N Peschel, R Zavodska, H Sehadova, R Stanewsky Current Biology 21 (9), 719-729, 2011 | 49 | 2011 |
A Role for the PERIOD:PERIOD Homodimer in the Drosophila Circadian Clock J Landskron, KF Chen, E Wolf, R Stanewsky PLoS biology 7 (4), e1000003, 2009 | 46 | 2009 |
Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's disease ND Younan, KF Chen, RS Rose, DC Crowther, JH Viles Journal of Biological Chemistry 293 (34), 13090-13099, 2018 | 44 | 2018 |
Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability E Buhl, A Bradlaugh, M Ogueta, KF Chen, R Stanewsky, JJL Hodge Proceedings of the National Academy of Sciences 113 (47), 13486-13491, 2016 | 44 | 2016 |
CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping M Putker, DCS Wong, E Seinkmane, NM Rzechorzek, A Zeng, NP Hoyle, ... The EMBO journal 40 (7), e106745, 2021 | 37 | 2021 |
Functional genomics in Drosophila models of human disease KF Chen, DC Crowther Briefings in functional genomics 11 (5), 405-415, 2012 | 24 | 2012 |
Neurocalcin regulates nighttime sleep and arousal in Drosophila KF Chen, S Lowe, A Lamaze, P Krätschmer, J Jepson eLife 8, e38114, 2019 | 22 | 2019 |
Impaired Pre‐Motor Circuit Activity and Movement in a Drosophila Model of KCNMA1‐Linked Dyskinesia P Kratschmer, SA Lowe, E Buhl, KF Chen, DM Kullmann, A Pittman, ... Movement Disorders 36 (5), 1158-1169, 2021 | 19 | 2021 |
Computational analysis and refinement of sequence structure on chromosome 22q11. 2 region: application to the development of quantitative real-time PCR assay for clinical diagnosis YF Chen, PL Kou, SJ Tsai, KF Chen, HH Chan, CM Chen, HS Sun Genomics 87 (2), 290-297, 2006 | 18 | 2006 |
Disrupted Glutamate Signaling in Drosophila Generates Locomotor Rhythms in Constant Light RVDM Azevedo, C Hansen, KF Chen, E Rosato, CP Kyriacou Frontiers in Physiology 11, 145, 2020 | 14 | 2020 |
A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock A Giesecke, PS Johnstone, A Lamaze, J Landskron, E Atay, KF Chen, ... Current Biology 33 (2), 336-350. e5, 2023 | 12* | 2023 |
Flyglow: Single-fly observations of simultaneous molecular and behavioural circadian oscillations in controls and an Alzheimer’s model E Khabirova, KF Chen, JS O’Neill, DC Crowther Scientific reports 6 (1), 1-13, 2016 | 5 | 2016 |
Insights into amyloid disease from fly models KF Chen, DC Crowther Essays in biochemistry 56, 69-83, 2014 | 1 | 2014 |