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Michael Harms
Michael Harms
Associate Professor, Institute of Molecular Biology, University of Oregon
在 uoregon.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Evolutionary biochemistry: revealing the historical and physical causes of protein properties
MJ Harms, JW Thornton
Nature Reviews Genetics 14 (8), 559-571, 2013
3652013
Analyzing protein structure and function using ancestral gene reconstruction
MJ Harms, JW Thornton
Current opinion in structural biology 20 (3), 360-366, 2010
2622010
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor
JT Bridgham, GN Eick, C Larroux, K Deshpande, MJ Harms, ...
PLoS biology 8 (10), e1000497, 2010
2592010
Arginine residues at internal positions in a protein are always charged
MJ Harms, JL Schlessman, GR Sue, B García-Moreno E
Proceedings of the National Academy of Sciences 108 (47), 18954-18959, 2011
1922011
Historical contingency and its biophysical basis in glucocorticoid receptor evolution
MJ Harms, JW Thornton
Nature 512 (7513), 203-207, 2014
1712014
How sequence defines structure: a crystallographic map of DNA structure and conformation
FA Hays, A Teegarden, ZJR Jones, M Harms, D Raup, J Watson, ...
Proceedings of the National Academy of Sciences 102 (20), 7157-7162, 2005
1682005
The pKa values of acidic and basic residues buried at the same internal location in a protein are governed by different factors
MJ Harms, CA Castañeda, JL Schlessman, GR Sue, DG Isom, ...
Journal of molecular biology 389 (1), 34-47, 2009
1622009
The thermostability and specificity of ancient proteins
LC Wheeler, SA Lim, S Marqusee, MJ Harms
Current opinion in structural biology 38, 37-43, 2016
1422016
Evolution of minimal specificity and promiscuity in steroid hormone receptors
GN Eick, JK Colucci, MJ Harms, EA Ortlund, JW Thornton
PLoS genetics 8 (11), e1003072, 2012
1412012
Detecting high-order epistasis in nonlinear genotype-phenotype maps
ZR Sailer, MJ Harms
Genetics 205 (3), 1079-1088, 2017
1382017
High-order epistasis shapes evolutionary trajectories
ZR Sailer, MJ Harms
PLoS computational biology 13 (5), e1005541, 2017
1132017
Robustness of reconstructed ancestral protein functions to statistical uncertainty
GN Eick, JT Bridgham, DP Anderson, MJ Harms, JW Thornton
Molecular biology and evolution 34 (2), 247-261, 2016
1092016
A buried lysine that titrates with a normal pKa: Role of conformational flexibility at the protein–water interface as a determinant of pKavalues
MJ Harms, JL Schlessman, MS Chimenti, GR Sue, A Damjanović, ...
Protein Science 17 (5), 833-845, 2008
1002008
Thermodynamic system drift in protein evolution
KM Hart, MJ Harms, BH Schmidt, C Elya, JW Thornton, S Marqusee
PLoS biology 12 (11), e1001994, 2014
992014
Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors
MJ Harms, GN Eick, D Goswami, JK Colucci, PR Griffin, EA Ortlund, ...
Proceedings of the National Academy of Sciences 110 (28), 11475-11480, 2013
802013
Molecular ensembles make evolution unpredictable
ZR Sailer, MJ Harms
Proceedings of the National Academy of Sciences 114 (45), 11938-11943, 2017
762017
Laser light‐scattering evidence for an altered association of βB1‐crystallin deamidated in the connecting peptide
MJ Harms, PA Wilmarth, DM Kapfer, EA Steel, LL David, HP Bächinger, ...
Protein science 13 (3), 678-686, 2004
502004
Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family
LC Wheeler, MT Donor, JS Prell, MJ Harms
PloS one 11 (10), e0164740, 2016
432016
Evolutionary trend toward kinetic stability in the folding trajectory of RNases H
SA Lim, KM Hart, MJ Harms, S Marqusee
Proceedings of the National Academy of Sciences 113 (46), 13045-13050, 2016
422016
pytc: Open-Source Python Software for Global Analyses of Isothermal Titration Calorimetry Data
H Duvvuri, LC Wheeler, MJ Harms
Biochemistry 57 (18), 2578-2583, 2018
272018
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