Circadian clock protein Rev-erbα regulates neuroinflammation P Griffin, JM Dimitry, PW Sheehan, BV Lananna, C Guo, ML Robinette, ... Proceedings of the National Academy of Sciences 116 (11), 5102-5107, 2019 | 192 | 2019 |
Dural lymphatics regulate clearance of extracellular tau from the CNS TK Patel, LM Habimana-Griffin, X Gao, B Xu, S Achilefu, K Alitalo, ... Molecular neurodegeneration 14 (1), 11, 2019 | 161 | 2019 |
Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1 BV Lananna, CJ Nadarajah, M Izumo, MR Cedeño, DD Xiong, J Dimitry, ... Cell reports 25 (1), 1-9. e5, 2018 | 117 | 2018 |
Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease J Lee, DE Kim, P Griffin, PW Sheehan, DH Kim, ES Musiek, SY Yoon Aging Cell, e13078, 2019 | 105 | 2019 |
REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis P Griffin, PW Sheehan, JM Dimitry, C Guo, MF Kanan, J Lee, J Zhang, ... eLife 9, e58765, 2020 | 50 | 2020 |
Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease JM Basak, A Ferreiro, LS Cohen, PW Sheehan, CJ Nadarajah, MF Kanan, ... Neurobiology of Disease 152, 105292, 2021 | 28 | 2021 |
B cells produce type 1 IFNs in response to the TLR9 agonist CpG-A conjugated to cationic lipids M Akkaya, B Akkaya, P Miozzo, M Rawat, M Pena, PW Sheehan, AS Kim, ... The Journal of Immunology 199 (3), 931-940, 2017 | 27 | 2017 |
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology PW Sheehan, CJ Nadarajah, MF Kanan, JN Patterson, B Novotny, ... Neuron, 2023 | 23 | 2023 |
Evaluating Circadian Dysfunction in Mouse Models of Alzheimer’s Disease: Where Do We Stand? PW Sheehan, ES Musiek Frontiers in Neuroscience 14, 703, 2020 | 18 | 2020 |
T cell‐dependent antigen adjuvanted with DOTAP‐CpG‐B but not DOTAP‐CpG‐A induces robust germinal center responses and high affinity antibodies in mice M Akkaya, B Akkaya, PW Sheehan, P Miozzo, M Pena, CF Qi, ... European journal of immunology 47 (11), 1890-1899, 2017 | 17 | 2017 |
A single-nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor alters the development of host immunity M Akkaya, A Bansal, PW Sheehan, M Pena, A Molina-Cruz, LM Orchard, ... Science Advances 6 (6), eaaw6957, 2020 | 14 | 2020 |
Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice J Lee, JM Dimitry, JH Song, M Son, PW Sheehan, MW King, ... Nature Communications 14 (1), 5197, 2023 | 13 | 2023 |
Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice M Akkaya, A Bansal, PW Sheehan, M Pena, CK Cimperman, CF Qi, ... Scientific Reports 10 (1), 13630, 2020 | 10 | 2020 |
Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration MK Kanan, PW Sheehan, JN Haines, PG Gomez, A Dhuler, CJ Nadarajah, ... JCI insight, 2023 | 2 | 2023 |
Microglia phagocytic mechanisms: Development informing disease RM Beiter, PW Sheehan, DP Schafer Current Opinion in Neurobiology 86, 102877, 2024 | 1 | 2024 |
A glial circadian gene expression atlas reveals cell type and disease-specific reprogramming in response to amyloid pathology or aging. PW Sheehan, SB Fass, D Sapkota, S Kang, HC Hollis, JH Lawrence, ... bioRxiv, 2024 | | 2024 |
Kir6. 2-KATP channels alter glycolytic flux to modulate cortical activity, arousal, and sleep-wake homeostasis NJ Constantino, CM Carroll, HC Williams, CM Yuede, PW Sheehan, ... bioRxiv, 2024.02. 23.581817, 2024 | | 2024 |