Integration of metabolome data with metabolic networks reveals reporter reactions T Çakır, KR Patil, ZI Önsan, KÖ Ülgen, B Kirdar, J Nielsen Molecular systems biology 2, 50, 2006 | 170 | 2006 |
PHISTO: pathogen–host interaction search tool S Durmuş Tekir, T Çakır, E Ardıç, AS Sayılırbaş, G Konuk, M Konuk, ... Bioinformatics 29 (10), 1357-1358, 2013 | 162 | 2013 |
A review on computational systems biology of pathogen–host interactions S Durmuş, T Çakır, A Özgür, R Guthke Frontiers in Microbiology 6, 235, 2015 | 127 | 2015 |
Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia T Çakιr, S Alsan, H Saybaşιlι, A Akιn, KÖ Ülgen Theoretical Biology and Medical Modelling 4 (1), 48, 2007 | 116 | 2007 |
Infection Strategies of Bacterial and Viral Pathogens through Pathogen–Human Protein–Protein Interactions SD Tekir, T Çakır, KÖ Ülgen Frontiers in Microbiology 3, 46, 2012 | 89 | 2012 |
Metabolic pathway analysis of yeast strengthens the bridge between transcriptomics and metabolic networks T Çakır, B Kırdar, KÖ Ülgen Biotechnology and bioengineering 86 (3), 251-260, 2004 | 86 | 2004 |
Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a targeted metabolomic and transcriptomic study VR Varma, HB Lüleci, AM Oommen, S Varma, CT Blackshear, ... npj Aging and Mechanisms of Disease 7 (1), 1-14, 2021 | 78 | 2021 |
Metabolic network discovery through reverse engineering of metabolome data T Çakır, MMWB Hendriks, JA Westerhuis, AK Smilde Metabolomics 5 (3), 318-329, 2009 | 78 | 2009 |
Systematic analysis of transcription-level effects of neurodegenerative diseases on human brain metabolism by a newly reconstructed brain-specific metabolic network M Sertbaş, K Ülgen, T Çakır FEBS open bio 4, 542-553, 2014 | 66 | 2014 |
Metabolic pathway analysis of enzyme-deficient human red blood cells T Çakır, CS Tacer, KÖ Ülgen Biosystems 78 (1-3), 49-67, 2004 | 52 | 2004 |
Effect of iron and magnesium addition on population dynamics and high value product of microalgae grown in anaerobic liquid digestate H Ermis, U Guven-Gulhan, T Cakir, M Altinbas Scientific reports 10 (1), 3510, 2020 | 51 | 2020 |
Effect of carbon source perturbations on transcriptional regulation of metabolic fluxes in Saccharomyces cerevisiae T Çakır, B Kırdar, Zİ Önsan, K Ülgen, J Nielsen BMC systems biology 1 (1), 18, 2007 | 47 | 2007 |
Metabolic network discovery by top-down and bottom-up approaches and paths for reconciliation T Çakır, MJ Khatibipour Frontiers in Bioengineering and Biotechnology 2, 62, 2014 | 42 | 2014 |
A genome-scale metabolic network of the aroma bacterium Leuconostoc mesenteroides subsp. cremoris E Özcan, SS Selvi, E Nikerel, B Teusink, E Toksoy Öner, T Çakır Applied Microbiology and Biotechnology 103, 3153-3165, 2019 | 39 | 2019 |
Flux Balance Analysis of a Genome‐Scale Yeast Model Constrained by Exometabolomic Data Allows Metabolic System Identification of Genetically Different Strains T Çakır, Ç Efe, D Dikicioǧlu, A Hortaçsu, B Kırdar, SG Oliver Biotechnology progress 23 (2), 320-326, 2007 | 39 | 2007 |
Network-based metabolism-centered screening of potential drug targets in Klebsiella pneumoniae at genome scale MF Cesur, B Siraj, R Uddin, S Durmuş, T Çakır Frontiers in Cellular and Infection Microbiology 9, 447, 2020 | 38 | 2020 |
Flux analysis of recombinant Saccharomyces cerevisiae YPB-G utilizing starch for optimal ethanol production T Çakır, KY Arga, MM Altıntaş, KÖ Ülgen Process biochemistry 39 (12), 2097-2108, 2004 | 37 | 2004 |
Reconstructed Metabolic Network Models Predict Flux-Level Metabolic Reprogramming in Glioblastoma E Ozcan, T Cakir Frontiers in Neuroscience 10, 156, 2016 | 36* | 2016 |
Modelling of calcium dynamics in brain energy metabolism and alzheimer's disease S Tiveci, A Akın, T Çakır, H Saybaşılı, K Ülgen Computational biology and chemistry 29 (2), 151-162, 2005 | 26 | 2005 |
Dynamic co‐culture metabolic models reveal the fermentation dynamics, metabolic capacities and interplays of cheese starter cultures E Özcan, M Seven, B Şirin, T Çakır, E Nikerel, B Teusink, E Toksoy Öner Biotechnology and Bioengineering 118 (1), 223-237, 2021 | 25 | 2021 |