Clonal dynamics of native haematopoiesis J Sun, A Ramos, B Chapman, JB Johnnidis, L Le, YJ Ho, A Klein, ... Nature 514 (7522), 322-327, 2014 | 887 | 2014 |
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases RL Frock, J Hu, RM Meyers, YJ Ho, E Kii, FW Alt Nature biotechnology 33 (2), 179-186, 2015 | 758 | 2015 |
Senolytic CAR T cells reverse senescence-associated pathologies C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Curbelo, ... Nature 583 (7814), 127-132, 2020 | 672 | 2020 |
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations Y Zhang, RP McCord, YJ Ho, BR Lajoie, DG Hildebrand, AC Simon, ... Cell 148 (5), 908-921, 2012 | 602 | 2012 |
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells R Chiarle, Y Zhang, RL Frock, SM Lewis, B Molinie, YJ Ho, DR Myers, ... Cell 147 (1), 107-119, 2011 | 511 | 2011 |
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency J Feucht, J Sun, J Eyquem, YJ Ho, Z Zhao, J Leibold, A Dobrin, A Cabriolu, ... Nature medicine 25 (1), 82-88, 2019 | 454 | 2019 |
p53 represses the mevalonate pathway to mediate tumor suppression SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ... Cell 176 (3), 564-580. e19, 2019 | 333 | 2019 |
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ... Science 362 (6421), 1416-1422, 2018 | 314 | 2018 |
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ... Cell 181 (2), 424-441. e21, 2020 | 294 | 2020 |
A gene–environment-induced epigenetic program initiates tumorigenesis D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ... Nature 590 (7847), 642-648, 2021 | 182 | 2021 |
A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma A Hayashi, J Fan, R Chen, Y Ho, AP Makohon-Moore, N Lecomte, ... Nature cancer 1 (1), 59-74, 2020 | 157 | 2020 |
Ordered and deterministic cancer genome evolution after p53 loss T Baslan, JP Morris IV, Z Zhao, J Reyes, YJ Ho, KM Tsanov, J Bermeo, ... Nature 608 (7924), 795-802, 2022 | 141 | 2022 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 141 | 2020 |
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching J Dong, RA Panchakshari, T Zhang, Y Zhang, J Hu, SA Volpi, RM Meyers, ... Nature 525 (7567), 134-139, 2015 | 112 | 2015 |
Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations YJ Ho, N Anaparthy, D Molik, G Mathew, T Aicher, A Patel, J Hicks, ... Genome research 28 (9), 1353-1363, 2018 | 89 | 2018 |
Senescence rewires microenvironment sensing to facilitate antitumor immunity HA Chen, YJ Ho, R Mezzadra, JM Adrover, R Smolkin, C Zhu, K Woess, ... Cancer discovery 13 (2), 432-453, 2023 | 83 | 2023 |
A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor FOXH1 E Loizou, A Banito, G Livshits, YJ Ho, RP Koche, FJ Sánchez-Rivera, ... Cancer discovery 9 (7), 962-979, 2019 | 73* | 2019 |
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer WK Chatila, JK Kim, H Walch, MR Marco, CT Chen, F Wu, DM Omer, ... Nature medicine 28 (8), 1646-1655, 2022 | 69 | 2022 |
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis C Burdziak, D Alonso-Curbelo, T Walle, J Reyes, FM Barriga, D Haviv, ... Science 380 (6645), eadd5327, 2023 | 64 | 2023 |
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma J Hu, FJ Sánchez-Rivera, Z Wang, GN Johnson, Y Ho, K Ganesh, ... Nature 616 (7958), 806-813, 2023 | 63 | 2023 |