Affinity gradients drive copper to cellular destinations L Banci, I Bertini, S Ciofi-Baffoni, T Kozyreva, K Zovo, P Palumaa Nature 465 (7298), 645-648, 2010 | 509 | 2010 |
Binding of zinc (II) and copper (II) to the full‐length Alzheimer’s amyloid‐β peptide V Tougu, A Karafin, P Palumaa Journal of neurochemistry 104 (5), 1249-1259, 2008 | 256 | 2008 |
Interactions of Zn(ii) and Cu(ii) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity V Tõugu, A Tiiman, P Palumaa Metallomics 3 (3), 250-261, 2011 | 255 | 2011 |
Zn (II)‐and Cu (II)‐induced non‐fibrillar aggregates of amyloid‐β (1–42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators V Tõugu, A Karafin, K Zovo, RS Chung, C Howells, AK West, P Palumaa Journal of neurochemistry 110 (6), 1784-1795, 2009 | 216 | 2009 |
Mitochondrial copper (I) transfer from Cox17 to Sco1 is coupled to electron transfer L Banci, I Bertini, S Ciofi-Baffoni, T Hadjiloi, M Martinelli, P Palumaa Proceedings of the National Academy of Sciences 105 (19), 6803-6808, 2008 | 205 | 2008 |
Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS) L Banci, I Bertini, F Cantini, T Kozyreva, C Massagni, P Palumaa, ... Proceedings of the National Academy of Sciences 109 (34), 13555-13560, 2012 | 170 | 2012 |
Formation of [4Fe-4S] clusters in the mitochondrial iron–sulfur cluster assembly machinery D Brancaccio, A Gallo, M Mikolajczyk, K Zovo, P Palumaa, E Novellino, ... Journal of the American Chemical Society 136 (46), 16240-16250, 2014 | 135 | 2014 |
A hint for the function of human Sco1 from different structures L Banci, I Bertini, V Calderone, S Ciofi-Baffoni, S Mangani, M Martinelli, ... Proceedings of the National Academy of Sciences 103 (23), 8595-8600, 2006 | 120 | 2006 |
Copper chaperones. The concept of conformational control in the metabolism of copper P Palumaa FEBS letters 587 (13), 1902-1910, 2013 | 119 | 2013 |
Metal-binding mechanism of Cox17, a copper chaperone for cytochrome c oxidase P Palumaa, L Kangur, A Voronova, R Sillard Biochemical Journal 382 (1), 307-314, 2004 | 118 | 2004 |
A structural-dynamical characterization of human Cox17 L Banci, I Bertini, S Ciofi-Baffoni, A Janicka, M Martinelli, H Kozlowski, ... Journal of biological chemistry 283 (12), 7912-7920, 2008 | 113 | 2008 |
The missing link in the amyloid cascade of Alzheimer’s disease–metal ions A Tiiman, P Palumaa, V Tougu Neurochemistry international 62 (4), 367-378, 2013 | 112 | 2013 |
The native copper-and zinc-binding protein metallothionein blocks copper-mediated Aβ aggregation and toxicity in rat cortical neurons RS Chung, C Howells, ED Eaton, L Shabala, K Zovo, P Palumaa, ... PloS one 5 (8), e12030, 2010 | 97 | 2010 |
Brain-specific metallothionein-3 has higher metal-binding capacity than ubiquitous metallothioneins and binds metals noncooperatively P Palumaa, E Eriste, O Njunkova, L Pokras, H Jörnvall, R Sillard Biochemistry 41 (19), 6158-6163, 2002 | 97 | 2002 |
Human Sco1 functional studies and pathological implications of the P174L mutant L Banci, I Bertini, S Ciofi-Baffoni, I Leontari, M Martinelli, P Palumaa, ... Proceedings of the National Academy of Sciences 104 (1), 15-20, 2007 | 88 | 2007 |
Copper (II)-binding equilibria in human blood T Kirsipuu, A Zadorožnaja, J Smirnova, M Friedemann, T Plitz, V Tõugu, ... Scientific reports 10 (1), 5686, 2020 | 86 | 2020 |
Organization and assembly of metal-thiolate clusters in epithelium-specific metallothionein-4 G Meloni, K Zovo, J Kazantseva, P Palumaa, M Vasak Journal of Biological Chemistry 281 (21), 14588-14595, 2006 | 77 | 2006 |
Metal binding of metallothionein-3 versus metallothionein-2: lower affinity and higher plasticity P Palumaa, I Tammiste, K Kruusel, L Kangur, H Jörnvall, R Sillard Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1747 (2), 205-211, 2005 | 76 | 2005 |
Metallothionein induces a regenerative reactive astrocyte phenotype via JAK/STAT and RhoA signalling pathways YKJ Leung, M Pankhurst, SA Dunlop, S Ray, J Dittmann, ED Eaton, ... Experimental neurology 221 (1), 98-106, 2010 | 68 | 2010 |
Oxidative switches in functioning of mammalian copper chaperone Cox17 A Voronova, W Meyer-Klaucke, T Meyer, A Rompel, B Krebs, ... Biochemical Journal 408 (1), 139-148, 2007 | 68 | 2007 |