Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria MR Hepworth, LA Monticelli, TC Fung, CGK Ziegler, S Grunberg, R Sinha, ... Nature 498 (7452), 113-117, 2013 | 864 | 2013 |
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ... Nature medicine 16 (10), 1147-1151, 2010 | 599 | 2010 |
Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory TA Doering, A Crawford, JM Angelosanto, MA Paley, CG Ziegler, ... Immunity 37 (6), 1130-1144, 2012 | 574 | 2012 |
Molecular and transcriptional basis of CD4+ T cell dysfunction during chronic infection A Crawford, JM Angelosanto, C Kao, TA Doering, PM Odorizzi, BE Barnett, ... Immunity 40 (2), 289-302, 2014 | 569 | 2014 |
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection C Kao, KJ Oestreich, MA Paley, A Crawford, JM Angelosanto, MAA Ali, ... Nature immunology 12 (7), 663-671, 2011 | 549 | 2011 |
Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells A Crawford, M MacLeod, T Schumacher, L Corlett, D Gray The Journal of Immunology 176 (6), 3498-3506, 2006 | 380 | 2006 |
Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection JM Angelosanto, SD Blackburn, A Crawford, EJ Wherry Journal of virology 86 (15), 8161-8170, 2012 | 326 | 2012 |
A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection A Crawford, JM Angelosanto, KL Nadwodny, SD Blackburn, EJ Wherry PLoS pathogens 7 (7), e1002098, 2011 | 214 | 2011 |
The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses A Crawford, EJ Wherry Current opinion in immunology 21 (2), 179-186, 2009 | 197 | 2009 |
Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion SD Blackburn, A Crawford, H Shin, A Polley, GJ Freeman, EJ Wherry Journal of virology 84 (4), 2078-2089, 2010 | 149 | 2010 |
A Mucin 16 bispecific T cell–engaging antibody for the treatment of ovarian cancer A Crawford, L Haber, MP Kelly, K Vazzana, L Canova, P Ram, A Pawashe, ... Science translational medicine 11 (497), eaau7534, 2019 | 107 | 2019 |
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies D Skokos, JC Waite, L Haber, A Crawford, A Hermann, E Ullman, R Slim, ... Science translational medicine 12 (525), eaaw7888, 2020 | 95 | 2020 |
AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion, and minimal MHCI upregulation on target cells LE Mays, L Wang, J Lin, P Bell, A Crawford, EJ Wherry, JM Wilson Molecular Therapy 22 (1), 28-41, 2014 | 63 | 2014 |
CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40 M MacLeod, MJ Kwakkenbos, A Crawford, S Brown, B Stockinger, ... The Journal of experimental medicine 203 (4), 897-906, 2006 | 60 | 2006 |
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning L Haber, K Olson, MP Kelly, A Crawford, DJ DiLillo, R Tavaré, E Ullman, ... Scientific Reports 11 (1), 14397, 2021 | 56 | 2021 |
Bispecific antigen-binding molecules that bind MUC16 and CD3, and compositions thereof L Haber, E Smith, M Kelly, JR Kirshner, S Coetzee, A Crawford, T Nittoli, ... US Patent 10,738,130, 2020 | 35 | 2020 |
A PSMA-targeting CD3 bispecific antibody induces antitumor responses that are enhanced by 4-1BB costimulation D Chiu, R Tavaré, L Haber, OH Aina, K Vazzana, P Ram, M Danton, ... Cancer Immunology Research 8 (5), 596-608, 2020 | 34 | 2020 |
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis WR Lagor, DW Fields, RC Bauer, A Crawford, MC Abt, D Artis, EJ Wherry, ... Atherosclerosis 233 (1), 234-241, 2014 | 33 | 2014 |
Anti-STEAP2 antibody drug conjugates, and compositions and uses thereof J Rudge, F Delfino, L Haber, E Smith, JR Kirshner, A Crawford, T Nittoli US Patent 10,772,972, 2020 | 31 | 2020 |
Distinct sources and targets of IL‐10 during dendritic cell‐driven Th1 and Th2 responses in vivo G Perona‐Wright, SJ Jenkins, A Crawford, D Gray, EJ Pearce, ... European journal of immunology 36 (9), 2367-2375, 2006 | 30 | 2006 |