Photoexcitation of flavoenzymes enables a stereoselective radical cyclization KF Biegasiewicz, SJ Cooper, X Gao, DG Oblinsky, JH Kim, SE Garfinkle, ... Science 364 (6446), 1166-1169, 2019 | 302 | 2019 |
An asymmetric sp3–sp3 cross-electrophile coupling using ‘ene’-reductases H Fu, J Cao, T Qiao, Y Qi, SJ Charnock, S Garfinkle, TK Hyster Nature 610 (7931), 302-307, 2022 | 77 | 2022 |
Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers MR Campbell, A Ruiz-Saenz, E Peterson, C Agnew, P Ayaz, S Garfinkle, ... Cell reports 38 (5), 2022 | 10 | 2022 |
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2 H Schönherr, P Ayaz, AM Taylor, JB Casaletto, BB Touré, DT Moustakas, ... Proceedings of the National Academy of Sciences 121 (6), e2317756121, 2024 | 5 | 2024 |
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion Y Sun, TJ Florio, S Gupta, MC Young, QF Marshall, SE Garfinkle, ... Science immunology 8 (90), eadj5792, 2023 | 2 | 2023 |
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition AC McShan, D Flores-Solis, Y Sun, SE Garfinkle, JS Toor, MC Young, ... Nature Communications 14 (1), 8204, 2023 | 1 | 2023 |
Suggested searches P Sacchi, SE Wright, P Neoptolemou, GI Lampronti, AK Rajagopalan, ... Perspective, 2024 | | 2024 |
New stereoselective CC and CH bond formations enabled by flavoprotein photocatalysis SJ Cooper, KF Biegasiewicz, X Gao, DG Oblinsky, JH Kim, S Garfinkle, ... American Chemical Society SciMeetings 1 (1), 2020 | | 2020 |
Stereoselective Radical Cyclization by Photoexcited Flavoenzymes B List, M Turberg Synfacts 15 (10), 1177, 2019 | | 2019 |
Structure Based Semi-rational Engineering of OYE-family Enzymes for Non-natural Catalytic Activity S Garfinkle | | 2019 |
An Asymmetric sp3–sp3 Cross-Electrophile Coupling Using Biocatalysis H Fu, J Cao, T Qiao, Y Qi, SJ Charnock, S Garfinkle, TK Hyster | | |